Dr. Guillaume Chanoit, DVM, MS, Dipl ECVS
Clinical Assistant Professor, Small Animal Surgery
Phone: 919.513.6723
Fax: 919.513.6336
Email: guillaume_chanoit@ncsu.edu
Education
MS, Microsurgery, 2001
MS, Pharmacokinetics, 2000
DEDV (DVM equivalent), National Veterinary School of Toulouise, France, 1998
Specialty
Soft Tissue Surgery
Professional Experience & Qualifications
August 2008-present: Adjunct Assistant Professor, department of Anaesthesiology, University of North Carolina, School of Medicine, Chapel Hill, USA.
2006-present: Clinical Assistant Professor, Small Animal Surgery, College of Veterinary Medicine, North Carolina State University, Raleigh, NC
2004: Diplomate, European College of Veterinary Surgeons
2003-2006: Clinical Assistant Professor, Small Animal Surgery, National Veterinary School of Lyon, France
2000-2003: Surgical Residency, Small Animal Surgery, National Veterinary School of Lyon, France
1998-2000: Research fellow, laboratory of Physiology and Pharmacology, National Veterinary School of Toulouse, France
Research Area
Ischemia-Reperfusion injury in the myocardium
Evaluation of cardio-thoracic devices and procedures
Liver vascular surgery
Lymphatic cannulation models
Selected Publications
Chanoit G, Lee SR, Xi J, Zhu M, McIntosh RA, Mueller RA, Norfleet EA, Xu Z. Exogenous Zinc protects cardiac cells from reperfusion injury by inactivating Glycogen Synthase Kinase 3β, Am J Physiol Heart Circ Physiol. 2008 Sep;295(3):H1227-H1233.
Bean E, Chanoit G, Jernigan J, Bolotin G, Buckner G. Evaluation of a New Atrial Retractor for Minimally Invasive Mitral Valve Exposure in a Porcine Model, In press J Thorac Cardiovasc Surg, 2008
Chanoit G, Bublot I, Viguier E. Tricuspid valve regurgitation as a complication of surgical treatment of Cor Triatriatum Dexter, In press J Small Anim Pract, September 2008
Sawaya S, Combet D, Chanoit G, Thiebault JJ, Levine D, Marcellin-Little DJ. Assessment of impulse duration thresholds for electrical stimulation of muscles (chronaxy) in dogs, Am J Vet Res. 2008 Oct;69(10):1305-9.
Chanoit G, Ferré PJ, Lefebvre HP. Chronic lymphatico-venous by-pass: Surgical technique and aftercare in a porcine model, Interact Cardiovasc Thorac Surg, 2007, Dec;6(6):705-7.
Chanoit G. Treatment of tracheal collapse using internal stents in dogs Prat Vét Anim Comp 2007, 23: 21-23 [in French]
Chanoit G, Kyles AE, Weisse C, Hardie EM. Surgical and interventional radiographic treatment of dogs with hepatic arteriovenous fistulae. Vet Surg 2007, 36: 199-209.
Chanoit G: Peritonitis: diagnosis, emergency treatment and abdominal drainage. Point Vét. 2006 Special issue : abdominal surgery , p.66-73 [in French ]
Guillaumin J, Chanoit G, Descones-Junot C, Goy-Thollot I. Bilothorax following cholecystectomy in a dog. J Small Anim Pract, 2006, 47: 733-736.
Chanoit G. Hepato-biliary tumors in dogs: which options? Prat Vét Anim Comp 2006, 23: 21-23 [ in French]
Lespine A, Chanoit G, Bousquet-Melou A, Lallemand E, Bassissi FM, Alvinerie M , Toutain PL. Lymphatic transport of moxidectin in conscious lymph duct-cannulated dogs Eur J Pharm Sci. 2006, 27 : 37-43
Chanoit GP, Woerlé F, Schneider M, Lefebvre HP : Effect of marbofloxacin on cardiovascular variables in healthy isoflurane-anesthetized dogs, Am J Vet Res 2005 , 66 : 2090-2094
Chanoit G, Genevois JP . Surgery of the esophagus, Encyclopedie Vétérinaire, Chirurgie générale, 2003 14 p [in French]
Chanoit GP, Concordet D, Lefebvre HP, Orcel K, Braun JP. Exercise does not induce major changes in plasma muscle enzymes, creatinine, glucose and total proteins concentrations in untrained beagle dogs, J Vet Med A, 2002, 49, 22-24
Chanoit GP, Lefebvre HP, Orcel K, Laroute V, Toutain PL, Braun JP: Use of plasma creatine kinase pharmacokinetics to estimate the amount of exercise-induced muscle damage in Beagle, Am J Vet Res, 2001, 62, 1375-1380
Chanoit G, Clerc V, Genevois JP: Chylothorax in dogs and cats, 2nd part: treatment Prat. Med. Chir. Anim. Comp., 2001,36: 341-350 [Article in French]
Chanoit G, Clerc V, Genevois JP: Chylothorax in dogs and cats, 1st part: Etiology, pathogeny and diagnosis Prat. Med. Chir. Anim. Comp., 2001,36: 331-340 [in French]
Chanoit G, Bardet JF. Retrospective study of 52 cases of rhinoscopy in dogs and cats:, Prat. Med. Chir. Anim. Comp., 1999, 34, 499-510 [in French]
Selected Abstracts and Imperative Summaries
Chanoit G, Lee SR, Xi J, Zhu M, McIntosh RA, Mueller RA, Norfleet EA, Xu Z. Exogenous Zinc protects cardiac cells from reperfusion injury by inactivating Glycogen Synthase Kinase 3β in Proceedings : AHA Scientific Sessions 2008, New Orleans, Louisiana
Xi J, Wang H, Chanoit G, Cheng G, Mueller RA, Norfleet EA, Xu Z. Resveratrol translocates GSK-3β to mitochondria and protects the heart at reperfusion by targeting the mitochondrial permeability transition pore in Proceedings : AHA Scientific Sessions 2007, Orlando, Florida
Wang H, Xi J, Cheng G, Chanoit G, Mueller RA, Norfleet EA, Xu Z. Reperfusion but not ischemia initiates autophagy and inhibition of autophagy protects the heart from reperfusion injury. in Proceedings : AHA Scientific Sessions 2007, Orlando, Florida
Chanoit G. Specific aspects of anaesthesia and surgery in puppies and kitten (lab. section) in Proceedings : AFVAC annual congress, Toulouse, Dec 2005 [In French]
Chanoit G. Aortic arch abnormalities in puppies and kitten in Proceedings : AFVAC annual congress, Toulouse, Dec 2005 [In French]
Chanoit G. Hepatic arteriovenous fistulae in dogs. In Proceedings ACVS Symposium San Diego Ca, 2005
Chanoit G, Kyles AE, Weisse C, Hardie EM. Hepatic arteriovenous fistulae in dogs: a retrospective study of 17 cases. Sientific Abstracts AVCS Symposium, 2005
Chanoit G: Thoracic Approaches, in Proceedings of the course of Thoracic Surgery, Elancourt, France, May 2002 [In French]
Chanoit G, Orcel K, Lefebvre HP, Braun JP: Quantitative assessment of muscle damage during exercise in untrained dogs. Congress of the International Society for Animal clinical Biochemistry, Toulouse, July 17-20, 2000, Revue de Medecine Vétérinaire, 2000, 151, 679
Chanoit G, Orcel K, Lefebvre HP, Braun JP Does exercise induce changes in some plasma constituents in untrained dogs?, In Proceedings : BSAVA Congress, Birmingham, UK, April 2000
Grants
Quantitative and qualitative chemical analysis of cellophane bands used for gradual occlusion of portosystemic shunts, ACVS foundation, applied November 08, $8,150
Description of a new method of chronic lymphatic cannulation in cats : a pilot study DoCS- practice plan / NCSU - applied Nov 07, $ 3,500 Not Funded
Evaluation of dendritic cell transport in lymph-canulated cats, (PI : Dr Kristina Howard, NCSU-CVM-MBS) CCMTR, applied June 07, $12,000 Not Funded
Evaluation of the role of TAB1-TAK1 pathway in ischemia-reperfusion injury in adult heart in vivo (PI : Dr Jun Tsuji, NCSU) , AHA grant-in-aid , applied March 08, $132,000, Not Funded
Description of a new method of chronic lymphatic cannulation in cats CVM research committee grant, applied March 08- $10,500 Not Funded
Pilot study to determine safety and efficacy of the BACE device for repair of mitral valve regurgitation in an ovine model, Mardil Inc (PI : Dr. Anthony Pease NCSU-CVM-MBS) $ 100,000, Funded
Innovative Tools & Techniques for Robotic Heart Surgery, NIH /NHLBI R01 (PI : Dr G. Buckner, NCSU), $462,656, Funded