Dr. David Dorman, DVM, PhD
Associate Dean for Research and Graduate Studies/Professor
E-mail: david_dorman@ncsu.edu
Education
- Postdoctoral Fellowship in Toxicology: Chemical Industry Institute of Toxicology
- Ph.D. in Veterinary Biosciences/Toxicology: University of Illinois at Urbana-Champaign
- Residency in Clinical Veterinary Toxicology: University of Illinois at Urbana-Champaign
- D.V.M.: Colorado State University, Fort Collins, CO.
- Graduate Training in Physical Organic Chemistry: University of Colorado-Boulder
- B.A. in Chemistry: University of San Diego, San Diego, CA.
Board Certifications
- Diplomate of the American Board of Veterinary Toxicology
- Diplomate of the American Board of Toxicology
Research Area:
The main focus of my research is directed towards improving human health risk assessments for environmentally relevant chemicals. My research is primarily focused on the respiratory toxicology, neurotoxicology, and pharmacokinetics of environmental agents. My research laboratory applies analytical chemistry, biochemistry, in vitro, whole animal, and computational dosimetry modeling approaches and a variety of other “state of the art” scientific techniques to toxicology.
Teaching Activities: VMA 954-Veterinary Toxicology and Poisonous Plants
Recent Publications:
Bolon B, Anthony D, Butt M, Dorman DC, Green M, Little P, Valentine WM, Weinstock D, Yan J, and Sills R (2008). “Current pathology techniques” symposium review: Advances and issues in neuropathology. Toxicol Pathol (in press).
Dorman DC, Struve MF, Norris A, Higgins AJ (2008). Metabolomic analyses of body fluids after subchronic manganese inhalation in rhesus monkeys. Toxicol Sci. [Epub ahead of print]
Erikson KM, Dorman DC, Lash LH, and Aschner M (2008). Timing of airborne-manganese exposure in rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity. Neurotoxicology 29(3):377-85.
Nong A, Teegaurden JG, Clewell HJ III, Dorman DC, and Andersen ME (2008). Pharmacokinetic modeling of manganese in the rat IV: Assessing factors that contribute to brain accumulation during inhalation exposure. J. Toxicol. Environ. Health A 71(7):413-26.
Dorman DC, Struve MF, Wong BA, Marshall MW, Gross EA, and Willson G (2008). Respiratory tract responses in male rats following subchronic acrolein inhalation. Inhal. Toxicol. 20(3):205-16.
Struve MF, Wong VA, Marshall MW, Kimbell JS, Schroeter JD, and Dorman DC (2008). Nasal uptake of inhaled acrolein in rats. Inhal. Toxicol. 20(3):217-25.
Dorman DC, Struve MF, Wong BA, Gross EA, Parkinson C, and Willson GA, Tan YM, Campbell JL, Teeguarden JG, Clewell HJ III, and Andersen ME (2008). Derivation of an inhalation reference concentration based upon olfactory neuronal loss in male rats following subchronic acetaldehyde inhalation. Inhal. Toxicol. 20(3):245-56.
Schroeter JD, Kimbell JS, Gross EA, Willson GA, Dorman DC, Tan YM, and Clewell HJ III (2008). Application of physiological computational fluid dynamics models to predict interspecies nasal dosimetry of inhaled acrolein. Inhal. Toxicol. 20(3):227-43.
Roberts ES, Struve MF, Thomas RT, and Dorman DC (2008). Gene expression changes following acute hydrogen sulfide (H2S)-induced nasal respiratory epithelial injury. Toxicol Pathol 36(4):560-7.
Wetmore BA, Struve MF, Gao P, Sharma S, Allison N, Roberts KC, Letinski DJ, Nicolich MJ, Bird MG, and Dorman DC (2008). Hematotoxicity of intermittent co-exposure to benzene and toluene in male CD-1 mice. Chem Biol Interact 173(3):166-78.