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Apr 12, 2024

Now Recruiting Dogs with Babesia gibsoni

Principle Investigator Dr. Birkenheuer Description NC State College of Veterinary Medicine is enrolling dogs with Babesia gibsoni in a trial to evaluate if the use of a new drug combination (atovaquone/proguanil hydrochloride, azithromycin, and artemisinin) can improve treatment outcomes. A new treatment regimen using atovaquone/proguanil hydrochloride, azithromycin, and an artemisinin derivative has recently been shown to… 

Apr 3, 2024

Enrolling Cats with Oral Squamous Cell Carcinoma

Principle Investigator Dr. Nolan Description NC State College of Veterinary Medicine is recruiting cats with oral squamous cell carcinoma (SCC) for a new clinical trial. The purpose is to evaluate a new drug meant to enhance standard radiation therapy (RT). All cats will be treated with a standard course of radiation therapy (RT); some cats will… 

Jan 26, 2024

Now Enrolling Dogs with Early Stage Oral Malignant Melanoma

Principle Investigator Dr. Michael Nolan Description NC State University Veterinary Hospital is looking for dogs with stage I or II with oral melanoma for a clinical trial using a new therapeutic drug (GM-1111) and standard-of-care radiotherapy. The purpose of this clinical trial is to evaluate whether the novel therapy has: 1. Direct anti-cancer activity, 2. Capacity… 

Nov 9, 2023

Riluzole as a Neuroprotectant in Canine Degenerative Myelopathy

Principle Investigator Dr Natasha Olby Description This study will evaluate the effect of Riluzole, a drug already FDA-approved for the treatment of human ALS, on the progression of clinical signs in dogs with degenerative myelopathy (DM). This therapy has been previously tested for safety in dogs. The study will be randomized and blinded. This means… 

May 12, 2023

Osteoarthritis Oral Microbiome Analysis in Cats

Principal Investigator Jody Gookin Description A one-time saliva sample from your cat to analyze their oral microbiome (the microbial composition of their mouths.) The analysis will allow us to identify patterns associated with the presence or absence of certain diseases. Testing Requirements A one-time visit to NCSU for a physical examination and saliva sample. There… 

Feb 2, 2023

THE IMPACT OF GI HEALTH ON JOINTS: A CLINICAL STUDY

Principal Investigator Duncan Lascelles Description We are excited to update you on the progress of our clinical study. Due to overwhelming interest and participation, we have temporarily paused enrollment to ensure the highest quality of care and attention to each participant. We anticipate resuming enrollment in late July and encourage you to stay tuned for… 

Jan 19, 2023

Now Enrolling Dogs with Bladder Cancer

Principal Investigator Dr. Michael Mastromauro Description NC State University College of Veterinary Medicine is enrolling in a clinical trial to investigate if a probiotic can improve cancer care and outcomes in dogs with bladder cancer. This is a placebo-controlled study, not all dogs will receive the probiotic, but all dogs will receivechemotherapy (vinblastine/piroxicam). Testing Requirements Dogs… 

Jan 18, 2023

Using the Chiari-like Malformation & Syringomyelia Evaluation (CHASE) Questionnaire* to Assess the Safety & Efficacy of a Novel Pain Management Product in Dogs

Principal Investigator Natasha Olby Description The goals of this study are to evaluate a newly developed questionnaire to assess pain and clinical signs associated with CM/SM in dogs and to evaluate how well a novel veterinary pain management product might treat the condition. Dogs with signs of CM/SM dogs will visit NC State Veterinary hospital for… 

Dec 19, 2022

Phase 1 Dose Escalation of Single-Agent Mechlorethamine HCl in Dogs with Lymphoma

Principal Investigator Dr. Joanne Intile Description We are recruiting dogs with lymphoma to determine the optimal dose of a chemotherapy drug called mustargen. Enrolled dogs will receive one free dose of mustargen and undergo follow up blood work for up to two weeks afterwards. Dogs can then receive other chemotherapy drugs, either at NCSU CVM… 

Sep 28, 2022

DOGS WITH NON-SEASONAL ATOPIC DERMATITIS TO INVESTIGATE THE EFFECTIVENESS OF TWO DIFFERENT DOSAGES OF A NOVEL IMMUNOTHERAPY DRUG

Principal Investigator Petra Bizikova Description Dogs with Non-Seasonal Atopic Dermatitis to Investigate the Effectiveness of Two Different Dosages of a Novel Immunotherapy Drug Testing Requirements – Patients will be required to come in for 10 visits over 24 weeks – Allergen-Specific IgE Serology (ASIS) testing at Heska – Patients will be required to stay for…