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clinical trials

Aug 3, 2022

NEW TREATMENT FOR IDIOPATHIC CYSTITIS AND CHRONIC URETHRAL OBSTRUCTIONS IN CATS

Principle Investigator Allison Kendall Testing Requirements As an alternative to euthanasia, the clinical trial will test low-dose radiotherapy which is intended to reduce symptoms. -cats will be required to stay at the hospital for 4-5 days during their initial visit for treatment and observation -owners will complete questionnaires at each visit and every 30 days… 

Aug 3, 2022

LONGITUDINAL STUDY OF NEURO-AGING IN DOGS

Principle Investigator Natasha Olby Description Canine Cognitive Dysfunction is an age-related neurobehavioral condition that shares similar features to Alzheimer’s disease observed in humans. The progression of this devastating disease ultimately leads to the decline in cognitive function, severely affecting comfort of life for dogs and their owners. The purpose of this study is to track… 

Aug 3, 2022

EARLY INTERVENTION FOR DOBERMAN PINSCHERS AT RISK OF DEVELOPING DILATED CARDIOMYOPATHY

Principle Investigator Kathryn Meurs Description We recently identified a genetic mutation in the Titin gene as a common cause of fatal dilated cardiomyopathy in the Doberman pinscher. Dogs that develop the disease frequently die of the disease either from refractory congestive heart failure or sudden cardiac death. Previous studies have demonstrated that medical intervention of… 

Aug 3, 2022

DOGS DIAGNOSED WITH PRIMARY SPONTANEOUS PNEUMOTHORAX

Principle Investigator Valery Scharf Description NC State University College of Veterinary Medicine is evaluating the feasibility of thoracoscopy (minimally invasive surgery) for the identification and localization of pulmonary bullae associated with spontaneous pneumothorax. The current approach to this disease is open surgical exploration via a median sternotomy; by demonstrating the ability of thoracoscopy to identify pulmonary… 

Aug 3, 2022

CLINICAL TRIAL FOR DOGS WITH PRIMARY ANGLE CLOSURE GLAUCOMA

Principle Investigator Hans Westermeyer Testing Requirements Your dog will receive an exam from the NC State Ophthalmology Service 1 month after study enrollment and once every 3 months thereafter. Each visit will include: sedation, a complete ophthalmic exam, photography and ultrasound of the eye’s drainage apparatus, retinal thickness measurement, and quantitative pupillary light reflex evaluation. A… 

Aug 3, 2022

RECRUITING DOGS WITH NATURALLY OCCURRING PULMONARY HYPERTENSION

Principle Investigator Teresa DeFrancesco Description – One all-day visit – Focused echocardiogram – Bloodwork Testing Requirements None Enrollment Start 03/01/2021 Enrollment Finish 05/04/2024 Eligibility – Must weigh 11 pounds (5kg) or more – Receiving sildenafil for 3 or more days and still having clinically significant pulmonary hypertension Flyer View Contact Dr. Terri DeFrancesco: tdefranc@ncsu.edu Dr.… 

Aug 3, 2022

RECRUITING DOGS IN CONGESTIVE HEART FAILURE WITH PULMONARY EDEMA

Principle Investigator Teresa DeFrancesco Description Testing Requirements NC State Cardiology is recruiting dogs in decompensated left-sided congestive heart failure (CHF) and pulmonary edema that requires hospitalization for treatment. These patients will be hospitalized in the NC State Small Animal Emergency and Critical Care department for treatment of CHF. Enrollment Start 03/01/2021 Enrollment Finish 06/01/2024 Eligibility Dogs in… 

Aug 3, 2022

MEDICAL RESOLUTION OF GALLBLADDER MUCOCELE FORMATION IN DOGS

Principle Investigator Jody Gookin Testing Requirements – Exclusive feeding of Royal Canin Gastrointestinal Low Fat dry or canned food with a 10% snack allowance for up to 1 year (paid for by study). Your dog’s feeding plan will be prescribed and monitored by a veterinary nutritionist. – Oral administration of up to 15 capsules of… 

Aug 3, 2022

DOES YOUR DOG HAVE: OSTEOARTHRITIS? MOBILITY PROBLEMS? LIMPING

Principle Investigator Duncan Lascelles Description NC State University College of Veterinary Medicine is looking for dogs that show signs of osteoarthritis. The goal of this clinical trial is to evaluate the benefits of a novel study drug to control pain associated with osteoarthritis in dogs. Testing Requirements None Enrollment Start 07/22/2021 Enrollment Finish 3/31/2023 Eligibility Your… 

Aug 3, 2022

IS YOUR DOG OVERWEIGHT?

Principle Investigator Duncan Lascelles Description NC State University College of Veterinary Medicine is looking for overweight dogs. The goal of this clinical trial is to evaluate the efficacy of an investigative diet as nutritional management for overweight dogs. Owners will receive 6 months of free premium dog food, a free automatic pet food feeder and dog…