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Clinical Trial: Early Detection Screening of Dogs for Bladder Cancer

The NC State College of Veterinary Medicine, with the help of the University of Wisconsin-Madison School of Veterinary Medicine, is screening dogs for a bladder and prostate cancer called urothelial carcinoma or transitional cell carcinoma (UC/TCC).

As part of this study, investigators will screen dog urine for a UC/TCC marker using the BRAF Mutation Detection Assay to hopefully diagnose UC/TCC before dogs develop signs of cancer.


  1. Your dog must be clinically healthy, with no signs of urinary tract infections
  2. Your dog must be at least 6 years old
  3. Your dog must be one of the following breeds: American Eskimo Dog, Beagle, Parson Russell Terrier, Russell Terrier, Scottish Terrier, Shetland Sheepdog, West Highland White Terrier
  4. You must be willing to participate in the study for 12 months


  • A free diagnostic test screening for UC/TCC.
  • If invited to the NC State Veterinary Hospital or UW Veterinary Care, your dog will receive a complete exam including bloodwork, abdominal ultrasound of the urinary tract, and cystoscopy of the urinary tract at no cost to you.
  • Dogs accepted into the study will also receive regular clinical follow-up for 12 months, at no cost to you.

How to Participate

To participate in this trial, you will be asked to do the following:

  1. Collect a urine sample from your dog
  2. Ship the sample to our laboratory using the self-addressed and postage-paid shipping containers.