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John Barnes, DVM, PhD, DACPV, DACVP

Professor, Poultry Health Management

Contact:

hjbarnes@ncsu.edu
Office: 919.513.6273

Certifications
Diplomate, American College of Poultry Veterinarians
Diplomate, American College of Veterinary Pathologists
Infectious Diseases
Currently, I am involved in research projects investigating the pathogenesis of spondylitis in broiler chickens caused by Enterococcus cecorum and a muscle disease in the breasts of broiler chickens called “Wooden Breast” because of the texture of affected meat. Previously, I have compared ovarian cancer in chickens and turkeys to that in women, determined the cause and pathogenesis of transmissible viral proventriculitis in broiler chickens and examined the causes of early lay mortality and male infertility in broiler breeders. Previously, considerable effort was directed toward studying studied a severe form of Poult Enteritis Complex known as Poult Enteritis Mortality Syndrome.

  • Parvovirus-associated cerebellar hypoplasia and hydrocephalus in day old broiler chickens.Marusak RA, Guy JS, Abdul-Aziz TA, West MA, Fletcher OJ, Day JM, Zsak L, Barnes HJ. | Avian Dis 54:156-60. 2010
  • Francisella philomiragia septicemia in ten-month old dog with corticosteroid-responsive meningitis. Cora M, Neel J, Tarigo J, Post K, Barnes HJ.  | J Vet Int Med 24:969-972, 2010.
  • Identification and characterization of two Bordetella avium gene products required for hemagglutination. Temple LM, Miyamoto DM, Mehta M, Capitini CM, Von Stetina S, Barnes HJ, Christensen VL, Horton JR, Spears PA, Orndorff  PE.  | Infect Immun. 78: 2370-2376.  2010.
  • Ovarian adenocarcinomas in the laying hen and women share similar alterations in p53, ras, and HER-2/neu. Hakim AA, Barry CP, Barnes HJ, Anderson KE, Petitte J, Whitaker R, Lancaster JM, Wenham RM, Carver DK, Turbov J, Berchuck A, Kopelovich L, Rodriguez GC.  | Cancer Prev Res. 2:114-121, 2009
  • Bilateral nocardial endophthalmitis in a Prothonotary Warbler (Protonotaria citrea).Reynolds TL, Barnes HJ, Wolfe B, Lu L, Camp DM, Malarkey DE.  | Vet Pathol. 46:120-123, 2009
  • Bacterial orchitis and epididymo-orchitis in broiler breeders. Monleon R, Martin M, Barnes HJ.  | Avian Pathol 37:613-617, 2008
  • Experimental reproduction of transmissible viral proventriculitis by infection of chickens with a novel adenovirus-like virus (isolate R 11/3). Guy JS, Smith LG, Evans ME, and Barnes HJ.  | Avian Dis 51:58-65, 2007
  • Experimental infection of chickens and turkeys with Mycoplasma gallisepticum reference strain S6 and North Carolina field isolate RAPD type B. Sanei B, Barnes HJ, Vaillancourt J-P, Ley DH.  | Avian Dis 51:106-111, 2007 
  • Disseminated Aspergillus flavus infection in broiler breeder pullets. Martin MP, Bouck KP, Helm J, Dykstra MJ, Wages DP, Barnes HJ.  | Avian Dis 51:626-631. 2007.
  • Litter impaction of the lower intestinal tract in male broiler breeders. Kristen Roza, Michael Martin, and H. John Barnes.  | Avian Dis 50: 460-462. 2006
  • Neonatal Osteomyelitis Associated with Staphylococcus aureus in Turkey Poults.Alfonso M, Barnes HJ.  | Avian Dis 50: 148-151. 2006
  • Strain persistence and fluctuation of multiple-antibiotic resistant Campylobacter coli colonizing turkeys over successive production cycles.Lee BC,  Reimers N, Barnes HJ, D'Lima C, Carver D, Kathariou S.  | Foodborne Pathog Dis 2:103-10, 2005.
  • Partial characterization of an adenovirus-like virus isolated from broiler chickens with transmissible viral proventriculitis. Guy JS, Barnes HJ, Smith L, Owen R, Fuller FJ.  | Avian Dis  49:344-351, 2005
  • Metastatic adenocarcinoma in the lungs of older laying hens.Alfonso M, Adochiles L, Hendrickson VM, Carver DK, Rodriguez GC, Barnes HJ.  | Avian Dis 49:430-432. 2005
  • Campylobacter colonization of sibling turkey flocks reared under different management conditions. Smith K, Reimers N, Barnes HJ, Lee BC, Siletzky R, Kathariou S.  | J Food Protect 67:1463-1468, 2004.
  • Venereal colibacillosis (acute vaginitis) in turkey breeder hens. Gazdzinski P, Barnes HJ.  | Avian Dis 48:681-685, 2004
  • Enhancement of enteropathogenic Escherichia coli pathogenicity in young turkeys by turkey coronavirus infection.Pakpinyo S, Ley DH, Barnes HJ, Vaillancourt, J-P, Guy JS. | Avian Dis 47:396-405, 2003.
  • Comparative genomic analysis reveals distinct genotype features of pathogenic Enterococcus cecorum.Borst LB, Suyemoto MM, Scholl BE, Barnes HJ. | PLoS Pathogens (submitted)
  • Bilateral malignant seminomas in two unrelated aged trumpeter hornbills (Bycanistes bucinator).M.B. Wernick MB, Tobias J, Moeller R, Barnes HJ, Palmieri C, Shivaprasad HL. | J Avian Med Surg, 2014. (submitted)
  • Pararenal myelolipomas in a commercial flock of egg-laying hens.Boone AC, Martin MP, Barnes HJ. | J Vet Diagn Invest, 2013. In press.
  • A chick embryo lethality assay for pathogenic Enterococcus cecorum.Borst LB Suyemoto MM, Veerappa SK, Dunningan SE, Guy JS, Barnes HJ. | Avian Dis 58:244-248. 2014
  • Evidence of a Chemopreventive Effect of Progestin Unrelated to Ovulation on Reproductive Tract Cancers in the Egg-Laying Hen.Rodriguez GC, Barnes HJ, Anderson K, Whitaker R, Berchuck A, Petitte J, Palyvers P, Lancaster J, Wenham R, Day R, Maxwell L, Carver D. | Cancer Prev Res 6:1283-1292, 2013
  • An outbreak and source investigation of enterococcal spondylitis in broilers caused by Enterococcus cecorum.Robbins KM, Suyemoto M, Lyman RL, Martin MP, Barnes HJ, Borst LB. | Avian Diseases 56:768-773. 2012
  • Molecular epidemiology of Enterococcus cecorum isolates recovered from enterococcal spondylitis outbreaks in the southeastern United States.Borst LB, Suyemoto MM, Robbins KM, Lyman RL, Martin MP, Barnes HJ. | Avian Pathology 41:479-485. 2012.
  • Associations between multidrug resistance, plasmid content, and virulence potential among extraintestinal pathogenic and commensal Escherichia coli from humans and poultry. Johnson TJ, Logue CM, Johnson JR, Kuskowski MA, Sherwood JS, Barnes HJ, DebRoy C, Wannemuehler YM, Obata-Yasuoka M, Spanjaard L, Nolan LK.  | Foodborne Pathogens and Disease 9:37-46. 2012.
  • Pathology in Practice: Chicken oviduct adenocarcinoma. Tobias JR, Barnes HJ, Law JM.  | J. Am. Vet. Med. Assoc. 239:1065-1067. 2011
  • Experimental reproduction of enterococcal spondylitis (ES) in male broiler breeder chickens. Martin LT, Martin MP, Barnes HJ. | Avian Dis, 55:273-278 2011.
  • Selected blood chemistry values in mobility impaired broiler breeder hens with suspected calcium tetany using the i-STAT® handheld clinical analyzer. Martin MP, Wineland M, Fletcher OJ, Barnes HJ. | Avian Dis 55:340-345. 2011
  • Reduction of ovarian and oviductal cancers in calorie-restricted laying chickens. Carver DK, Barnes HJ, Anderson KE, Petitte JN, Whittaker R, Berchuck A,  Rodriguez GC. | Cancer Prev Res (Phila) 4:562-567, 2011
  • Comparison of gene expression patterns between avian and human ovarian cancers. Gonzalez-Bosquet J, Peedicayil A, Maguire J, Chien J, Rodriguez GC, Whitaker R, Petitte JN, Anderson KE, Barnes HJ, Shridhar V, Cliby WA.  | Gynecol Oncol. 120:256-264, 2011.
  • Bilateral nocardial endophthalmitis in a Prothonotary Warbler (Protonotaria citrea).Reynolds TL, Barnes HJ, Wolfe B, Lu L, Camp DM, Malarkey DE.  | Vet Pathol. 46:120-123, 2009
  • Bacterial orchitis and epididymo-orchitis in broiler breeders. Monleon R, Martin M, Barnes HJ.  | Avian Pathol 37:613-617, 2008
  • Experimental reproduction of transmissible viral proventriculitis by infection of chickens with a novel adenovirus-like virus (isolate R 11/3). Guy JS, Smith LG, Evans ME, and Barnes HJ.  | Avian Dis 51:58-65, 2007
  • Experimental infection of chickens and turkeys with Mycoplasma gallisepticum reference strain S6 and North Carolina field isolate RAPD type B. Sanei B, Barnes HJ, Vaillancourt J-P, Ley DH.  | Avian Dis 51:106-111, 2007 
  • Comb candidiasis affecting roosters in a broiler breeder flock. Osorio C, Fletcher O, Dykstra MJ, Post K, Barnes HJ.  | Avian Dis 51:618-622. 2007
  • Disseminated Aspergillus flavus infection in broiler breeder pullets. Martin MP, Bouck KP, Helm J, Dykstra MJ, Wages DP, Barnes HJ.  | Avian Dis 51:626-631. 2007.
  • Litter impaction of the lower intestinal tract in male broiler breeders. Kristen Roza, Michael Martin, and H. John Barnes.  | Avian Dis 50: 460-462. 2006
  • Neonatal Osteomyelitis Associated with Staphylococcus aureus in Turkey Poults.Alfonso M, Barnes HJ.  | Avian Dis 50: 148-151. 2006
  • Strain persistence and fluctuation of multiple-antibiotic resistant Campylobacter coli colonizing turkeys over successive production cycles.Lee BC,  Reimers N, Barnes HJ, D'Lima C, Carver D, Kathariou S.  | Foodborne Pathog Dis 2:103-10, 2005.
  • Partial characterization of an adenovirus-like virus isolated from broiler chickens with transmissible viral proventriculitis. Guy JS, Barnes HJ, Smith L, Owen R, Fuller FJ.  | Avian Dis  49:344-351, 2005
  • Metastatic adenocarcinoma in the lungs of older laying hens.Alfonso M, Adochiles L, Hendrickson VM, Carver DK, Rodriguez GC, Barnes HJ.  | Avian Dis 49:430-432. 2005
  • Campylobacter colonization of sibling turkey flocks reared under different management conditions. Smith K, Reimers N, Barnes HJ, Lee BC, Siletzky R, Kathariou S.  | J Food Protect 67:1463-1468, 2004.
  • Venereal colibacillosis (acute vaginitis) in turkey breeder hens. Gazdzinski P, Barnes HJ.  | Avian Dis 48:681-685, 2004
  • Enhancement of enteropathogenic Escherichia coli pathogenicity in young turkeys by turkey coronavirus infection.Pakpinyo S, Ley DH, Barnes HJ, Vaillancourt, J-P, Guy JS. | Avian Dis 47:396-405, 2003.
  • Comparative genomic analysis reveals distinct genotype features of pathogenic Enterococcus cecorum.Borst LB, Suyemoto MM, Scholl BE, Barnes HJ | PLoS Pathogens (submitted)
  • Bilateral malignant seminomas in two unrelated aged trumpeter hornbills (Bycanistes bucinator).M.B. Wernick MB, Tobias J, Moeller R, Barnes HJ, Palmieri C, Shivaprasad HL. | J Avian Med Surg 2014. (submitted)
  • Pararenal myelolipomas in a commercial flock of egg-laying hens.Boone AC, Martin MP, Barnes HJ. | J Vet Diagn Invest 2013. In press
  • A chick embryo lethality assay for pathogenic Enterococcus cecorum.Borst LB Suyemoto MM, Veerappa SK, Dunningan SE, Guy JS, Barnes HJ. | Avian Dis 58:244-248. 2014
  • Evidence of a Chemopreventive Effect of Progestin Unrelated to Ovulation on Reproductive Tract Cancers in the Egg-Laying Hen.Rodriguez GC, Barnes HJ, Anderson K, Whitaker R, Berchuck A, Petitte J, Palyvers P, Lancaster J, Wenham R, Day R, Maxwell L, Carver D. | Cancer Prev Res 6:1283-1292, 2013
  • An outbreak and source investigation of enterococcal spondylitis in broilers caused by Enterococcus cecorum.Robbins KM, Suyemoto M, Lyman RL, Martin MP, Barnes HJ, Borst LB. | Avian Diseases 56:768-773. 2012
  • Molecular epidemiology of Enterococcus cecorum isolates recovered from enterococcal spondylitis outbreaks in the southeastern United States.Borst LB, Suyemoto MM, Robbins KM, Lyman RL, Martin MP, Barnes HJ. | Avian Pathology 41:479-485. 2012.
  • Associations between multidrug resistance, plasmid content, and virulence potential among extraintestinal pathogenic and commensal Escherichia coli from humans and poultry. Johnson TJ, Logue CM, Johnson JR, Kuskowski MA, Sherwood JS, Barnes HJ, DebRoy C, Wannemuehler YM, Obata-Yasuoka M, Spanjaard L, Nolan LK.  | Foodborne Pathogens and Disease 9:37-46. 2012.
  • Pathology in Practice: Chicken oviduct adenocarcinoma. Tobias JR, Barnes HJ, Law JM.  | J. Am. Vet. Med. Assoc. 239:1065-1067. 2011
  • Experimental reproduction of enterococcal spondylitis (ES) in male broiler breeder chickens. Martin LT, Martin MP, Barnes HJ. | Avian Dis 55:273-278 2011
  • Selected blood chemistry values in mobility impaired broiler breeder hens with suspected calcium tetany using the i-STAT® handheld clinical analyzer. Martin MP, Wineland M, Fletcher OJ, Barnes HJ. | Avian Dis 55:340-345. 2011
  • Reduction of ovarian and oviductal cancers in calorie-restricted laying chickens. Carver DK, Barnes HJ, Anderson KE, Petitte JN, Whittaker R, Berchuck A,  Rodriguez GC. | Cancer Prev Res (Phila) 4:562-567, 2011
  • Comparison of gene expression patterns between avian and human ovarian cancers. Gonzalez-Bosquet J, Peedicayil A, Maguire J, Chien J, Rodriguez GC, Whitaker R, Petitte JN, Anderson KE, Barnes HJ, Shridhar V, Cliby WA.  | Gynecol Oncol. 120:256-264, 2011.
  • Parvovirus-associated cerebellar hypoplasia and hydrocephalus in day old broiler chickens.Marusak RA, Guy JS, Abdul-Aziz TA, West MA, Fletcher OJ, Day JM, Zsak L, Barnes HJ. | Avian Dis 54:156-60. 2010
  • Combined hepatocellular-cholangiocarcinoma in a lesser flamingo (Phoenicopterus minor). Van Wettere AJ, Degernes, LA, Barnes HJ.  | Avian Pathol 39:275-278, 2010.
  • Francisella philomiragia septicemia in ten-month old dog with corticosteroid-responsive meningitis. Cora M, Neel J, Tarigo J, Post K, Barnes HJ.  | J Vet Int Med 24:969-972, 2010.
  • Identification and characterization of two Bordetella avium gene products required for hemagglutination. Temple LM, Miyamoto DM, Mehta M, Capitini CM, Von Stetina S, Barnes HJ, Christensen VL, Horton JR, Spears PA, Orndorff  PE.  | Infect Immun. 78: 2370-2376.  2010.
  • Ovarian adenocarcinomas in the laying hen and women share similar alterations in p53, ras, and HER-2/neu. Hakim AA, Barry CP, Barnes HJ, Anderson KE, Petitte J, Whitaker R, Lancaster JM, Wenham RM, Carver DK, Turbov J, Berchuck A, Kopelovich L, Rodriguez GC.  | Cancer Prev Res. 2:114-121, 2009
  • Comparative genomic analysis reveals distinct genotype features of pathogenic Enterococcus cecorum.Borst LB, Suyemoto MM, Scholl BE, Barnes HJ | PLoS Pathogens (submitted)
  • Bilateral malignant seminomas in two unrelated aged trumpeter hornbills (Bycanistes bucinator).M.B. Wernick MB, Tobias J, Moeller R, Barnes HJ, Palmieri C, Shivaprasad HL. | J Avian Med Surg 2014. (submitted)
  • Pararenal myelolipomas in a commercial flock of egg-laying hens.Boone AC, Martin MP, Barnes HJ. | J Vet Diagn Invest 2013. In press
  • A chick embryo lethality assay for pathogenic Enterococcus cecorum.Borst LB Suyemoto MM, Veerappa SK, Dunningan SE, Guy JS, Barnes HJ. | Avian Dis 58:244-248. 2014
  • Evidence of a Chemopreventive Effect of Progestin Unrelated to Ovulation on Reproductive Tract Cancers in the Egg-Laying Hen.Rodriguez GC, Barnes HJ, Anderson K, Whitaker R, Berchuck A, Petitte J, Palyvers P, Lancaster J, Wenham R, Day R, Maxwell L, Carver D. | Cancer Prev Res 6:1283-1292, 2013
  • An outbreak and source investigation of enterococcal spondylitis in broilers caused by Enterococcus cecorum.Robbins KM, Suyemoto M, Lyman RL, Martin MP, Barnes HJ, Borst LB. | Avian Diseases 56:768-773. 2012
  • Molecular epidemiology of Enterococcus cecorum isolates recovered from enterococcal spondylitis outbreaks in the southeastern United States.Borst LB, Suyemoto MM, Robbins KM, Lyman RL, Martin MP, Barnes HJ. | Avian Pathology 41:479-485. 2012.
  • Parvovirus-associated cerebellar hypoplasia and hydrocephalus in day old broiler chickens.Marusak RA, Guy JS, Abdul-Aziz TA, West MA, Fletcher OJ, Day JM, Zsak L, Barnes HJ. | Avian Dis 54:156-60. 2010
  • Bilateral nocardial endophthalmitis in a Prothonotary Warbler (Protonotaria citrea). | Vet Pathol. 46:120-123, 2009
  • Neonatal Osteomyelitis Associated with Staphylococcus aureus in Turkey Poults. | Avian Dis 50: 148-151. 2006
  • Strain persistence and fluctuation of multiple-antibiotic resistant Campylobacter coli colonizing turkeys over successive production cycles. | Foodborne Pathog Dis 2:103-10, 2005.
  • Metastatic adenocarcinoma in the lungs of older laying hens. | Avian Dis 49:430-432. 2005
  • Enhancement of enteropathogenic Escherichia coli pathogenicity in young turkeys by turkey coronavirus infection.Pakpinyo S, Ley DH, Barnes HJ, Vaillancourt, J-P, Guy JS. | Avian Dis 47:396-405, 2003.
  • (2010) Mycoplasma iowae associated with chondrodystrophy in commercial turkeys.Ley DH, Marusak RA, Vivas EJ, Barnes HJ, Fletcher OJ.  | Avian Pathol 39:87-93. 2010.  [Erratum: Avian Pathol 39 :307]
  • (2007) Comb Candidiasis Affecting Roosters in a Broiler Breeder Flock(2007) Osorio C, Fletcher O, Dykstra MJ, Post K, Barnes HJ.  | Avian Dis 51:618-622. 2007.