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Jody Khosla

Lecturer, Histology and Cell Biology


The laboratory is focused on pulmonary cell biology and the mechanisms, which modulate the adhesion, proliferation, growth, development of injury and disease in mammalian alveolar epithelial cells. We specifically use isolated type II cells from the rat lungs and study their interaction with sulfated and desulfated extracellular matricies and soluble growth factors. Replacement of epithelial cells in normal turnover processes or following injury, which typically involves proliferation and differentiation of specific cell types, is a key determinant in maintaining normal tissue architecture and functional relationships in all biologic systems.