Skip to main content
NC State CVM
Think and Do The Extraordinary
GIVE to the College
Think and Do The Extraordinary
The Campaign for NC State CVM


Jay Levine, DVM, MPH

Currently Interim Department Head in CoS


Lab: Aquatic Epidemiology and Conservation

Dr. Levine, Professor of Epidemiology and Public Health joined the NC State College of Veterinary Medicine in 1984. In his role as one of the College’s epidemiologists he provides instruction to veterinary students and graduate students and coordinates the Aquatic Epidemiology and Conservation Laboratory (AECL) and its various studies focused on the biology and conservation of freshwater fauna. His research work, which spans 3 decades initially focused on arthropod-borne diseases and in particular Lyme disease. Dr. Levine has also coordinated studies focused on shellfish safety, marine finfish, numerous veterinary health problems in companion animals, and ecosystem health. The work of the AECL focuses on some of the most imperiled animals on the planet, freshwater mussels and snails. Dr. Levine, his staff and students have been working to further our understanding of these freshwater invertebrates, develop new diagnostic techniques for studying their health and refining techniques that support their conservation and their captive propagation for the augmentation of remaining populations.

Dr. Levine's is actively engaged in NC communities and has supported community initiatives focused on environmental restoration, stormwater mitigation and early childhood literacy. Since 2009, he has coordinated the Homework Haven (, a free after school tutoring program in South Raleigh.
American Veterinary Medical Association
National Association of State Public Health Veterinarians
Agromedicine Institute
NC State Forensic Sciences Institute
Computational Biology and Bioinformatics, Spontaneous Animal Disease Models
Aquatic epidemiology
The role of bivalves as indicators of ecosystem health and the ecology
Captive propagation
Conservation of unionids (freshwater mussels)

  • (2015) Key metabolites in tissue extracts of Elliptio complanata using 1H Nuclear Magnetic Resonance (NMR) spectroscopy.Hurley-Sanders, JL, Levine, JF, Tikunov, AP, Macdonald, J, Nelson, SAC, Showers, W, Stoskopf, M | Conservation Physiology 3: 10.1093/conphys/cov023
  • (2015) Tissue extraction methods for metabolic profiling of a freshwater bivalve, Elliptio complanata.Hurley-Sanders, JL, Stoskopf, M, Nelson, SAC, Showers, W, Law, JM, Gracz HS, Levine, JF | American Malacological Bulletin 33:1-10.
  • (2015) Fish hosts of four freshwater mussel species in the Broad River, SC.Eads, CB, Price, JE, Levine, JF | Southeastern Naturalist 14:85-97.
  • (2014) Seasonal changes in microbial community structure in stream sediment in a North Carolina River Basin.Bucci, JP, Szempruch, AJ, Caldwell, JM, Ellis, JC, Levine, JF. | Diversity 6: 18-32.  doi:10.3390/d6010018
  • (2014) Submicrometre particle filtration with a DC Activated Plasma Textile.Rasipuram, S, Wu, M, Kuznetsov, IA, Kusnetsov, AV, Levine, JF, Jasper, WJ, Saveliev, AV. | Journal Physics D 47: 025201 doi:10.1088/0022-3727/47/2/025201
  • (2013) A Stable Isotope Tracer (δ13C) Study of Escherichia coli Retention in two freshwater bivalves (Corbicula fluminea and Elliptio complanata).Bucci, JP, Szempruch, AJ, Levine, JF. | American Malacological Bulletin 31:1-8.
  • (2013) Vertical migration and reproductive patterns of a long-term brooding freshwater mussel, Villosa constricta Bivalvia: Unionidae) in a small piedmont stream.Eads, CB, Levine, JF. | Walkerana 16:29-40.
  • (2012) The Wilson Bay initiative, Riverworks, and the sturgeon city partnership: A case study for building effective academic-community partnershipsLevine, JF, Hargett, G, McCann, JP, Donovan-Potts, P, Pierce, S. | Journal of Higher Education, Outreach and Engagement 15: 121-133. 15: 121-133.
  • (2011) Spatial variability of the stable isotope (δ 15N) composition in two freshwater bivalves (Corbicula fluminea and Elliptio complanata).Bucci, J, Levine JF, Showers, WJ. | J. Freshwater Ecology 26:19-24.
  • (2011) Integration of environmental stewardship and local economic development to enhance community healthLevine, JF | North Carolina Medical Journal 72: 141-144.
  • (2011) The Wilson Bay Initiative, Riverworks, and the Sturgeon City Partnership: A case study for building effective academic-community partnerships.Levine, JF, Hargett, G, McCann, JP, Donovan-Potts, P, Pierce, S. | Journal of Higher Education, Outreach and Engagement 15: 121-133.
  • (2011) Sea Cucumber: A new candidate species for aquaculture in the Mediterranean Sea.Sicuro, B, Levine, JF. | Reviews in Fisheries Science. Aquaculture 19: 299-304.
  • (2010) Fish hosts of the Carolina heelsplitter (Lasmigona decorata), a federally endangered freshwater mussel (Bivalvia: Unionidae).Eads, CB, Bringolf, RB, Greiner, RD, Bogan AE, Levine, JF | American Malacological Bulletin 28:151-158
  • (2009) Stable oxygen and carbon isotope profiles in a an invasive bivalve (Corbicula fluminea) in North Carolina watersheds.Bucci, JP, Showers, WJ, Genna, B, Levine JF | Geochimica et Cosmochimica Acta. 73:3234-3247
  • (2009) Domestic wastewater influent profiling using mitochondrial real-time PCR for source tracking animal contamination.Caldwell, J, Levine, JF. | J Microbiol Methods 77:17-22
  • (2009) Comparison of traditional thermocouples and data loggers for simplified temperature monitoring using shellstock oysters as a model.Drake, SL, Beverely R., Chawla, A, Janes M., Supan J., Bell J, Levine JF. Jaykus, LA. | Journal of Food Protection and Trends. Journal of Food Protection and Trends. 29:268-271.
  • (2009) Development of a dynamic pharmacokinetic model to estimate bioconcentration of xenobiotics in earthworms.Henson-Ramsey, Levine, JF, Kennedy-Stoskopf, S, Taylor, S, Shea, D, Stoskopf, S | Environmental Modeling and Assessment 14:411-418
  • (2009) Effects of opionids and anesthetic drugs on body temperature in cats.Posner, LP, Pavuk, AA, Rokshar, JL, Carter, JE, Levine JF. | Veterinary Anaestheisa and Analgesia 37:35-43.
  • (2008) Magnetic resonance imaging of live freshwater mussels (Unionidae).Holliman, F, Davis, D, Bogan, A, Kwak T, Cope, G., Levine, JF | Invertebrate Biology 127:396-402(7)
  • (2008) Valve gape response to turbidity in two freshwater bivalves (Corbicula fluminea and Lampsilis radiata).Bucci, JP, Showers, B, Levine, JF, Usry B | J. Freshwater Ecology 23:479-483
  • (2008) Detection of spring viremia of carp virus (SVCV) by loop mediated isothermal amplification (LAMP) in koi carp (Cyprinus carpio).Shivappa, RB, Savan, R, Kono, T, Sakal M, Kurath G, Levine, JF. | Journal of Fish Diseases 31:249-258.
  • (2008) Impacts of Road Crossings on Stream Fish Movement and Community Structures.Vander Pluym JL, Eggleston DB, Levine JF | Journal of Freshwater Ecology 23: 545-574
  • (2007) Multi-tiered health assessment of Atlantic menhaden in the Pamlico River, North Carolina.Johnson AK, Law JM, Harms CA, Levine JF. | J Aquat Anim Health 19: 205-214.
  • (2007) Phylogenetic analysis of spring virema of carp virus reveals distinct subgroups with common origins for recent isolates in North America and the UK.Miller O, Fuller FJ, Gebreyes W, Lewbart GA, Shivappa RB, Stone DM, Dixon PF, Raley ME, Levine JF. | Diseases of Aquatic Organisms. 76:193-204.
  • (2007) Polychlorinated biphenyl exposure causes gonadal atrophy and oxidative stress in Corbicula fluminea clams.Lehmann DW, Levine JF, Law JM | Toxologic Pathology 35:356-365
  • (2007) Mitochondrial Multiplex Real-Time Pcr As A Source Tracking Method In Fecal-Contaminated Surface Waters.Caldwell JM, Raley ME, Levine JF | Environmental Science and Technology 10:3277-3283
  • (2007) Temporal and spatial variability in stable isotope compositions of freshwater mussels: implications for biomonitoring and ecological studies.Gustafson LL, Showers W , Kwak T, Levine JF, Stoskopf M. | Oecologica 152:140-150.
  • (2007) Salmonella populations and prevalence in layer feces from commercial high-rise houses and characterization of the Salmonella isolates by serotyping, antibiotic resistance analysis, and pulsed field gel electrophoresis.Li, X., Payne J, Santos F, Anderson KE, Levine JF, Sheldon BW. | Poultry Science 86:591-7.
  • (2007) Exposure of Unionid Mussels to Electric Current: Assessing Risks Associated with Electrofishing.Holliman FM, Kwak TJ, Cope WG, Levine JF. | Transactions of the American Fisheries Society 136:1593-1606.
  • (2006) A quantitative real-time RT-PCR assay to measure TGF-beta mRNA and its correlation with hematologic, plasma chemistry and organo-somatic indices responses in triamcinolone-treated Atlantic menhaden, Brevoortia tyrannus.Johnson AK, Harms CA, Levine JF, Law JM. | Dev Comp Imm 30: 473-484.
  • (2006) Status and Life History of the Notched Rainbow (Villosa constricta) in the Upper Neuse River Basin.Eads, CB, Bogan AE., Levine JF. | Southeastern Naturalist 5:649-660.
  • (2006) A comparison of analysis units for associating Lyme disease with forest-edge habitat.Jackson LE, Levine JF, Hilborn ED. | Community Ecology 7:189-197.
  • (2005) Evaluation of a nonlethal technique for hemolymph collection in Elliptio complanata, a freshwater bivalve.Gustafson LL, Stoskopf MK, Bogan A, Showers W, Kwak, T, Hanlon S, Levine JF. | Diseases of Aquatic Organisms 65:159-165.
  • (2005) Reference ranges for hemolymph chemistries from Elliptio complanata of North Carolina.Gustafson LL, Stoskopf MK, Showers W , Cope G, Eads C , Linnehan R, Kwak T, Anderson B, Levine JF. | Diseases of Aquatic Organisms 65:167-176
  • (2005) Renal biopsy: A retrospective study of 283 dogs and 65 cats.Vaden SL, Levine J, Lees GE, Groman RP, Grauer RP, Forrester SD. | J Vet Int Med, 2005; 19:794-801.
  • (2004) Pharmacokinetics and pharmacodynamics of furosemide after oral administration to horses.Johansson AM, Gardner SY, Levine JF, Papich MG, LaFevers DH, Goldmann RB, Sheats MK, Atkins CE. | Journal of Veterinary Internal Medicine Vol. 18, No. 5, 739-743.