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Gabriela Seiler, DVM, DACVR, DECVDI

Professor of Radiology

Office: 919.513.6217

Dr. Gabriela Seiler received her Doctor of Veterinary Medicine degree from the University of Bern, Switzerland and worked in small animal practice in Switzerland for 2 years while performing a doctoral thesis before entering a radiology residency program at the University of Bern.
She became board certified in radiology by the European College of Veterinary
Diagnostic Imaging in 2001. After two years as a Lecturer in Radiology she
became an Assistant Professor of Radiology at the University of Pennsylvania in
2004 and completed board certification by the American College of Veterinary
Radiology in 2006. She joined the faculty at North Carolina State University in
2009 as Associate Professor (tenure track) with promotion to Professor in 2017.
Diplomate, European College of Veterinary Diagnostic Imaging
Diplomate, American College of Veterinary Radiology
Certificate in Clinical Research
Diplomate, European College of Veterinary Diagnostic Imaging
Diplomate, American College of Veterinary Radiology
Regenerative Medicine, Spontaneous Animal Disease Models, Veterinary Cancer Care
The main research focus is in the use of advanced ultrasound imaging methods
in veterinary and translational medicine with a special interest in tumor perfusion. Information about blood supply of a tumor is important for characterization of tumor type and selection of optimal treatment methods and response to treatment. Cancer research in dogs and cats is relevant to human patients as well as the spontaneous nature and the size of the patient closely resembles cancer in people. One method to investigate tumor perfusion non-invasively is contrast-enhanced ultrasound. Ultrasound contrast media are stabilized gas-filled microbubbles that are small enough to pass through capillaries. Their highly elastic shells are compressed or resonated when activated by an ultrasound beam, and they consequently produce a strong signal which can be registered by the ultrasound transducer. Vasculature and tissue perfusion of a tumor can thus be assessed repeatedly and non-invasively. Contrast-enhanced ultrasound has already been established as a safe imaging method in dogs and cats for assessment of various organs. It has been shown to accurately distinguish benign from malignant liver nodules in dogs. Furthermore, ultrasound contrast media can be targeted to specific vascular receptors or used as a carrier for substances used for chemotherapy or gene therapy.

Characterization of Early and Late Stage Feline CKD Using Contrast-Enhanced Ultrasound and Ultrasound Elastography

Ultrasound Molecular Imaging to Assess Therapeutic Response