Description: Both pain and itch sensations are complex biological phenomena associated with several diseases, incurring huge societal expenses; however, the mechanism involved in these sensations remain elusive. Our lab interest is to understand the underlying cellular, molecular, and neural mechanism(s) driving these sensations. Our research emphasizes on molecular players including endogenous mediators, receptors, and neurotransmitters in relaying these noxious sensations at behavior and functional levels by using multidisciplinary approach. Here, we will discuss the most recent advances in pain and itch sensations uncovering their molecular fuels that generate pain hypersensitivity and itch in mice.
Location: RB101, CVM, NC State University