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Procedures and Requirements

A. Adviser

Upon entrance into the CBS Graduate Program, the Director of the CBS Graduate Program will direct the graduate student’s program and act in the capacity of an adviser until the student selects a faculty research adviser. Students should select an adviser early in their graduate training (by the end of the first year). All first year students who have not selected an adviser upon entering the program are recommended to schedule laboratory rotations on a semester basis with faculty members of their choice. The objective of these rotations is to provide the student with an introduction to various technical aspects of biomedical research and to introduce the student to the research program of individual faculty members. These should be arranged by contacting individual faculty members after consultation with the program director.

B. Grades

A student who fails (a grade of D or F) a core course will be dismissed from the CBS Graduate Program. All first year students who have less than a B grade in any of the CBS core courses or an overall average of less than 3.0 will be reviewed by the Graduate Studies Committee and Program Director. A student’s status in the program is based upon academic performance and reasonable progress in research. If a student is permitted to remain in the program, the form of remediation will be decided by the Graduate Studies Committee and the student’s adviser.

C. Annual Review

Each student in the program will meet Program Director annually to review his/her progress. Once a dissertation advisory committee has been formed for the student, this committee will meet annually with the student to review progress.

D. Research

The conduct and execution of the research problem will be the responsibility of the student’s adviser and his/her dissertation committee. The student is expected to make reasonable progress in their research, and to attend at least one national meeting as a student to present data from their research.

E. Graduate Student Representation

To ensure that Graduate Students have the opportunity to actively participate in their program of study, students will have elected representation on the CBS Graduate Studies Committee. This will be in the form on one student who is elected by the CBS graduate students. The term of service will be for two years. The student representative shall attend all Committee meetings and make contributions that serve student interests. It will be the responsibility of the student representative to disseminate information from the meetings and to raise issues on behalf of the students. First year students will not be eligible for election to the CBS Graduate Studies Committee. Election of the student representative will take place during the Spring semester, with the term of service beginning on the following July 1.

Policies and Requirements for the Ph.D. Program

A. Objectives

The Doctor of Philosophy degree in Comparative Biomedical Sciences shall reflect a mastery of the principles of a discipline in Comparative Biomedical Sciences, with students engaging in research in one of the five concentration areas in the Comparative Biomedical Sciences Graduate Program.

B. Formal Requirements for the Doctoral Degree in Comparative Biomedical Sciences

  1. The CBS program director will guide the student in the pursuit of course work and training until the student selects an adviser.
  2. The Doctor of Philosophy degree requires the equivalent of at least 3 academic years of work beyond the baccalaureate degree with a minimum of 72 semester hours of graduate credit. If a student has earned a master’s degree in a relevant area, then a minimum of 54 semester hours of graduate credit beyond the master’s degree is required.
  3. It is required that all first year Comparative Biomedical Sciences Graduate Students enrolled in the doctoral program complete the required core curriculum for their concentration. The student will have completed the(se) course(s) prior to the scheduling of the Doctoral Candidacy Examination.In certain instances and with permission of the Graduate Studies Committee in conjunction with other appropriate faculty members, students may be exempt from taking a basic core course if adequate proficiency or equivalency can be demonstrated. An alternative course of study may be approved by the graduate committee.
  4. All CBS Graduate Students are encouraged to enroll in additional coursework. The student will consult his/her adviser for recommended additional coursework in accordance with the student’s chosen course of study. A list of available electives can be found on the requirements page of each concentration area. Other courses may be added with approval of the CBS Graduate Studies Committee.
  5. All doctoral students are encouraged to complete the doctoral degree within a five (5) year time period.
  6. All doctoral students are required to satisfactorily complete both written and oral portions of the candidacy examination.
  7. All doctoral students must successfully complete the Final Oral Examination (Defense of Dissertation) covering the dissertation and related fields of investigation.

C. Doctoral Candidacy Examination

  1. Committee Selection, Scheduling, and Deadlines
    1. The adviser and advisee will set the date for the oral portion of the Doctoral Candidacy Examination or Preliminary Examination and select an Advisory Committee. This Committee will consist of the student’s adviser, who may serve as chairperson, and three graduate faculty members as well as a Graduate School Representative. The Advisory Committee for each student must be approved by the Director of the CBS Graduate Program.
    2. The student may elect to schedule the written portions of the examination at any time during the three month period preceding the scheduled date of the oral examination, however, all written portions of the candidacy examination must be completed ten (10) days prior to the scheduled date of the oral examination.
    3. The Director of the CBS Graduate Program will be informed, in writing, of the members comprising the Advisory Committee, and the dates of the written and oral examinations.
    4. The Preliminary Examination format should adhere to guidelines of the  Graduate School Catalog. The student’s advisory committee in consultation with the student, will determine the format of the student’s exam.
  2. Design of the Written Portion
    • The prospective doctoral candidate will be expected to demonstrate an in-depth knowledge of biomedical sciences in their area of concentration. Specific questions will be designed by the faculty members to examine the candidate in this area.
  3. Design of the Oral Portion
    • The oral portion of the Candidacy Examination, approximately two hours in duration, will be administered by the Advisory Committee. The prospective candidate’s adviser may serve as Chairperson and a Graduate School Representative will be appointed by the Dean of the Graduate School.

D. Final Oral Examination

The Final Oral Examination, two hours in length, will be administered by the student’s advisory committee and a Graduate School Representative, assigned by the graduate school upon approval of the graduate plan of work. Oral presentations are open to the CVM community.

E. Dissertation Final Copy

Students are required to submit an electronic dissertation to the Graduate School through the ETD submission system in the MyPack within 24 hours of receiving an unconditional pass on the final examination.

F. Additional Graduate School Requirements for the Doctoral Degree

All requirements of the Graduate School must be fulfilled in order to schedule the final dissertation defense and to formally complete graduate studies in the program.

Graduate students will be enrolled as full-time students. A total of 72 credit hours is required to obtain a PhD degree, with the majority of these credits being derived from dissertation research. See the Graduate School web page for specific credit hour and residency requirements.

Students in the program select from one of six concentration areas for their graduate research

CBS Core Courses Required of all Students

CBS 565 Fundamentals of Comparative Biomedical Sciences (3 credits)

ST 511 Experimental Statistics for Biological Sciences (3 credits)

CBS 662 Responsible Conduct of Research (1 credit)

CBS 800 Seminar series (1 credit; minimum 3 credits total for doctoral students; minimum 2 credits total for master’s students)

 Concentration Areas

Cell Biology

The Cell Biology Concentration Area encompasses research at the molecular and cellular levels in the following disciplines: gastroenterology, oncology, pulmonary biology, ophthalmology, reproductive endocrinology, pharmacology, neurophysiology and neuroanatomy, and cellular differentiation and morphogenesis. Research approaches employ a wide variety of molecular, biochemical, pharmacological, and microscopic techniques, utilizing cell culture and whole organisms. Students selecting Cell Biology will focus their research efforts on one or more of these areas.

A highly individualized curriculum of study is designed to meet the needs and interests of the student while satisfying selected requirements by the faculty. These include graduate level cell biology, biochemistry, and cell biology seminars. Additional courses may be chosen by the student and his/her advisor from a large number of college and university offerings.

Courses Required for the Cell Biology Concentration

GN701 Molecular Genetics (3 credits)

CBS 770 Cell Biology (4 credits)

CBS 810C Seminar in Cell Biology (1 credit; minimum 3 credits total for doctoral students; minimum 2 credits total for master’s students)

Other Courses

CBS 890 Doctoral Preliminary Exam (1 credit)

CBS 893 Doctoral Supervised Research (variable credit)

CBS 895 Doctoral Dissertation Research

CBS 896 Summer Dissertation Research (variable credit)

CBS 899 Doctoral Dissertation Preparation

Elective Courses

Elective courses are selected by the student and mentor, and must be approved by the student’s graduate advisory committee. Possible elective course include, but are not limited to, the following:

BCH 701 Macromolecular Structure

BCH 703 Macromolecular Synthesis and Regulation

BCH 705 Molecular Biology of the Cell

BIT 810 Biotechnology Core Technology

GN 701 Molecular Genetics

GN 702 Cellular and Developmental Genetics

GN 761 Advanced Molecular Biology of the Cell

GN 710 Eukaryotic Regulatory Mechanisms

GN 750 Developmental Genetics

GN/MB 758 Prokaryotic Molecular Genetics

GN/BCH 768 Nucleic Acids: Structure and Function

GS 735 Introduction to Genomic Science

CBS 770 Cell Biology

CBS 861 Bacterial Pathogenic Mechanisms

CBS/IMM/MB 783 Advanced Immunology

CBS/IMM 816 Advanced Topics in Immunology and Biotechnology

MB 718 Introductory Virology

MB/IMM 751 (Immunology; Spring)

IMM/TOX 705 Immunotoxicology

IMM 751 Immunology

IMM /PHY 756 Immunogenetics

PHY 702 Reproductive Physiology

PHY 503, 504 General Physiology I and II

PHY 513 Comparative Physiology

PHY 780 Mammalian Endocrinology

ST 701 Experimental Statistics II

TOX 501 General Toxicology

VMM 877 Clinical Laboratory & Necropsy

Concentration Area Leader:
Dr. Ken Adler
Phone: (919) 513-1348
Fax: (919) 515-4237
E-mail:ken_adler@ncsu.edu

Ken Adler
Interactions of airway epithelium with inflammatory mediators and inhaled pollutants
Title: Professor of Cell Biology
Phone: 919 513 6549
E-mail: kenneth_adler@ncsu.edu

Scott Bailey
Diseases of Pregnancy in the Mare
Title: Assistant Professor of Theriogenology
Phone: 919 513 6149
Email: scott_bailey@ncsu.edu

Anthony Blikslager
Mechanism of Intestinal Mucosal Repair
Title: Assistant Professor of Equine Surgery
Phone: 919 513 7725
E-mail: anthony_blikslager@ncsu.edu

James Bonner
Cellular and Molecular Mechanisms of Pulmonary Fibrosis
Title: Associate Professor of Toxicology
Phone: 919 515 8615
Email: james_bonner@ncsu.edu

Matthew Breen
Cytogentics of Cancer
Title: Associate Professor of Genetics
Phone: 919 513 1467
E-mail: matthew_breen@ncsu.edu

John Gadsby
Regulation of the Corpus Luteum
Title: Associate Professor of Physiology
Phone: 919 515 7224
Email: john_gadsby@ncsu.edu
Troy Ghashghaei
Development and Function of Adult Neural Stem Cells
Title: Assistant Professor of Neurobiology
Phone: 919 513 6174
Email: troy_ghashghaei@ncsu.edu

Brian Gilger
Pharmacology of the Eye
Title: Associate Professor of Ophthalmology
Phone: 919 513 6239
E-mail: brian_gilger@ncsu.edu

Jody Gookin
Host-pathogen Interactions in the Gut
Title: Associate Professor of Small Animal Internal Medicine
Phone: 919 513 6295
Email: jody_gookin@ncsu.edu

Marlene Hauck
Targeted Therapeutics in Cancer
Title: Associate Professor of Oncology
Phone: 919 513 8274
Email: marlene_hauck@ncsu.edu

Eleanor Hawkins
Respiratory medicine, particularly pulmonology and Chronic Bronchitis
Title: Professor of Small Animal Internal Medicine
Phone: 919 513 7727
E-mail: eleanor_hawkins@ncsu.edu

Paul Hess
Targeted Therapeutics of Immune-mediated Diseases
Title: Assistant Professor of Oncology
Phone: 919 513 6183
Email: paul_hess@ncsu.edu

Jonathan Horowitz
Regulation of mammalian cell cycle and transcription by tumor-suppressor genes
Title: Associate Professor of Cell Biology
Phone: 919 515 4479
E-mail: jon_horowitz@ncsu.edu
Web site: http://www4.ncsu.edu/~jmhorowi/horowitz_web/horowitzlab.htm

Samuel Jones
Regulation of Neutrophil Motility
Title: Assistant Professor of Equine Medicine
Phone: 919 513 6200
Email: sam_jones@ncsu.edu

B. Duncan X. Lascelles

Mechanism and Treatment of Pain
Title: Associate Professor of Small Animal Surgery
Phone: 919 513 6588
Email: duncan_lascelles@ncsu.edu

Chris Mariani
Biology of Cancers of the Brain
Title: Assistant Professor of Neurology
Phone: 919 513 0302
E-mail: chris_mariani@ncsu.edu

Nancy Monteiro-Riviere
Toxicity of environmental and novelpharmaceutical compounds
Title: Professor of Investigational Dermatology and Toxicology
Phone: 919 513 6426
E-mail: nancy_monteiro@ncsu.edu

Paul Mozdziak
Mechanisms of Skeletal Muscle Growth
Title: Professor of Poultry Medicine
Phone: 919 513 6248
FAX: 919 513 6464
Email: paul_mozdziak@ncsu.edu

Kate Meurs
Genomics of Cardiac Disease
Title: Professor of Cardiology and Associate Dean of Research & Graduate Studies
Phone: 919 513 6213
FAX: 919 513 6452
Email: kate_meurs@ncsu.edu

Nanette Nascone-Yoder
Development of the Gastrointestinal Tract
Title: Associate Professor of Development
Phone: 919 513 6229
E-mail: Nanette_Nascone-Yoder@ncsu.edu
Nascone-Yoder Lab Website: http://www4.ncsu.edu/~nmnascon/

Shila Nordone
Regulation of Inflammation
Title: Research Assistant Professor
Email: shila_nordone@ncsu.edu

Natasha Olby
Treatment of Spinal Cord Injury and Genomics of Neurological Diseases
Title: Professor of Neurology
Phone: 919 513 8286
E-mail: natasha_olby@ncsu.edu

Thierry Olivry
Pathogenesis and Therapy of Pruritis, Atopic Dermatitis and Autoimmune Diseases
Title: Professor of Dermatology
Phone: 919 513 7711
E-mail: thierry_olivry@ncsu.edu

Jorge Piedrahita
Role of Imprinted Genes in Embryo Development and Disease, Stem Cell Biology
Title: Professor of Genomics
Phone: 919 515 7407
E-mail: jorge_piedrahita@ncsu.edu

Marcelo Rodriguez-Puebla
Cell cycle regulation, skin carcinogenesis, mouse model, tumor biology
Title: Associate Professor of Carcinogenesis
Phone: 919 515 7409
E-mail: Marcelo_Rodriguez-Puebla@ncsu.edu

Korinn Saker
Nutrition of Cancer
Title: Associate Professor of Clinical Nutrition
Phone: 919 513 6871
E-mail: korinn_saker@ncsu.edu

Philip Sannes
Interactions between epithelial cell populations and connective tissue matrices
Title: Professor of Cell Biology and Histology
Phone: 919 513 6295
E-mail: philip_sannes@ncsu.edu

Lauren Schnabel
Stem Cell Biology and Immunology
Title: Assistant Professor
Phone: 919.515.7410
E-mail: lauren_schnabel@ncsu.edu

Robert Smart
Chemical carcinogenesis and development in model laboratory systems
Title: Professor of Toxicology
Phone: 919 515 7245
E-mail: rcsmart@unity.ncsu.edu
Web site: http://www.tox.ncsu.edu/faculty/smart/index.htm

Steve Suter
Genetics and Therapy of Cancer
Title: Assistant Professor of Oncology
Phone: 919 513 0813
Email: steven_suter@ncsu.edu

Don Thrall
Hyperthermia as a Cancer Treatment
Title: Professor of Radiology and Radiation Oncology
Phone: 919 513 6292
E-mail: don_thrall@ncsu.edu

David W Threadgill
Genetics of Inter-individual differences in health and disease
Title: Professor of Genetics
Phone: 919 515 2292
E-mail: threadgill@ncsu.edu

Jeffrey Yoder
Characterizations and Function of Innate Immune Response Genes
Title: Associate Professor of Innate Immunology
Phone: 919 515 7406
E-mail: Jeff_Yoder@ncsu.edu
Yoder Lab Web site: ~jayoder

Immunology

The Immunology concentration area coursework and laboratory research emphasize cellular and molecular biology studies in infectious disease immunology, mucosal immunity and inflammation, immunopathology, immunotoxicology, immunoparasitology, environmental immunology, and immunology of non-vertebrate species. The diversified faculty is drawn from the Colleges of Veterinary Medicine and Agriculture and Life Sciences as well as government agencies located in the Research Triangle Park. Interdepartmental cooperation provides a unique atmosphere for the study of immunology in a wide range of species.

The concentration is designed to prepare students for professional research and teaching careers in applying molecular biology techniques to animal and human health problems associated with environmental stress such as infectious agents and toxins. Immunology graduates are extremely competitive for positions in universities, pharmaceutical companies and governmental institutions. North Carolina State University in Raleigh with close proximity to the University of North Carolina at Chapel Hill, Duke University, and the Research Triangle Park provides a unique biomedical and research environment for seminars, meetings, and interaction with other scientists. Graduate research assistantships are available to qualified students.

Course offerings or research facilities are available in the following areas: immunopathology, immunotoxicology, immunoparasitology, mucosal immunology, molecular and infectious disease immunology, aquatic immunology. and environmental immunology.

Master’s Degree Requirements: Courses must include at least two 700-800-level immunology courses and one 500-700-level biochemistry course.

Doctoral Degree Requirements: Courses include at least two 700-800-level immunology courses, two 500-700-level biochemistry courses, and one 500-level course in statistics. Additional course offered by the Departments of Microbiology, Genetics, Toxicology and the graduate programs in Physiology and Comparative Biomedical Sciences may be taken. The remaining credit hours should include journal club (IMM 816), seminar (IMM 807) and research credits.

Courses Required for the Immunology Concentration

MB/IMM 751 Immunology (3 credits)

PO/IMM 757 Comparative Immunology (3 credits) or IMM/CBS 783Advanced Immunology (3 credits)

BCH 553 Biochemistry of Gene Expression (3 credits)

IMM/CBS 816 Advanced Topics in Immunology (1 credit; 8 credits required for doctoral students)

Other Courses

IMM/CBS 807 Seminar in Veterinary Microbiology/Immunology

Elective Courses

Elective courses are selected by the student and mentor, and must be approved by the student’s graduate advisory committee. Possible elective course include, but are not limited to, the following:

BCH 701 Macromolecular Structure

BCH 703 Macromolecular Synthesis and Regulation

BCH 705 Molecular Biology of the Cell

BIT 810 Biotechnology Core Technology

GN 701 Molecular Genetics

GN 702 Cellular and Developmental Genetics

GN 761 Advanced Molecular Biology of the Cell

GN 710 Eukaryotic Regulatory Mechanisms

GN 750 Developmental Genetics

GN/MB 758 Prokaryotic Molecular Genetics

GN/BCH 768 Nucleic Acids: Structure and Function

GS 735 Introduction to Genomic Science

CBS 770 Cell Biology

MB 535 Bacterial Pathogenesis

CBS 861 Bacterial Pathogenic Mechanisms

CBS/IMM/MB 783 Advanced Immunology

CBS/IMM 816 Advanced Topics in Immunology and Biotechnology

MB 718 Introductory Virology

ST 701 Experimental Statistics II

TOX 501 General Toxicology

Concentration Area Leader:
Dr. Scott Laster
Phone: (919) 515-7958
Fax: (919) 515-7867
E-mail:scott_laster@ncsu.edu

Adam Birkenheuer
General Internal Medicine and Infectious Disease
Title: Associate Professor
Phone: 919 513 8288
E-mail: adam_birkenheuer@ncsu.edu

Petra Bizikova
Veterinary Dermatology
Title: Assistant Professor of Dermatology
Phone: 919 515 7395
E-mail: petra_bizikova@ncsu.edu

Ed Breitschwerdt
Detection, characterization, and treatment of canine/feline bacterial pathogens
Title: Professor
Phone: 919 513 8277
E-mail: ed_breitschwerdt@ncsu.edu

Jonathan Fogle
Regulation of Immune Responses to Lentiviruses
Title: Assistant Professor of Immunology
Phone: 919 513 6248
E-mail: jonathan_fogle@ncsu.edu

Isabel Gimeno
Poultry Pathology and Immunology
Title: Associate Professor
Phone: 919 513 6852
E-mail: isabel_gimeno@ncsu.edu

Jody Gookin
Host-pathogen Interactions in the Gut
Title: Associate Professor of Small Animal Internal Medicine
Phone: 919 513 6295
E-mail: jody_gookin@ncsu.edu

Bruce Hammerberg
Allergic Disease
Title: Professor
Phone: 919 513 7712
E-mail: Bruce_Hammerberg@ncsu.edu

Edward Havell
The Innate Anti-bacterial Immune Response
Title: Professor of Immunology
Phone: 919 515 6184
E-mail: ed_havell@ncsu.edu

Paul Hess
Targeted Therapeutics of Immune-mediated Diseases
Title: Assistant Professor of Oncology
Phone: 919 513 6183
E-mail: paul_hess@ncsu.edu

Lola Hudson
Virus infection and Immune Mechanisms of the Brain
Title: Professor
Phone: 919 513 6306
E-mail: lola_hudson@ncsu.edu

Samuel Jones
Regulation of Neutrophil Motility
Title: Professor of Equine Medicine
Phone: 919 513 6200
E-mail: sam_jones@ncsu.edu

Matthew Koci
Avian Immunology
Title: Associate Professor
Phone: 919 515 2626
FAX:
E-mail: MDKoci@ncsu.edu

Scott Laster
Innate Immunity and Inflammation
Title: Professor
Phone: 919 515 7958
FAX: 919 515 7867
E-mail: scott_laster@ncsu.edu

Mike Levy
Immunoparasitology
Title: Professor
Phone: 919 513 8289
FAX: 919 515 3044
E-mail: Mike_Levy@ncsu.edu

Jennifer Miller
Bacterial Pathogenesis and Innate Immunity
Title: Assistant Professor of Microbiology
Phone: 919 515 7867
FAX: 919 515 7867
E-mail: jen_miller@ncsu.edu

Shila Nordone
Regulation of Inflammation
Title: Research Assistant Professor
E-mail: shila_nordone@ncsu.edu

Thierry Olivry
Pathogenesis and Therapy of Pruritis, Atopic Dermatitis and Autoimmune Diseases
Title: Professor of Dermatology
Phone: 919 513 7711
E-mail: thierry_olivry@ncsu.edu

Laura Ott
Inflammation and Biotechnology
Title: Teaching Scholar
Phone: 919 513 7685
E-mail: laura_ott@ncsu.edu

Lauren Schnabel
Stem cell biology and Immunology
Title: Assistant Professor
Phone: 919.515.7410
E-mail: lauren_schnabel@ncsu.edu

Frank Scholle
Viral Immunology
Title: Associate Professor
Phone: 919 513 7574
E-mail: frank_scholle@ncsu.edu

Michael Sikes
Lymphocyte development and differentiation
Title: Associate Professor
Phone: 919 513 0528
E-mail: mike_sikes@ncsu.edu

Steve Suter
Genetics and Therapy of Cancer
Title: Associate Professor of Oncology
Phone: 919 513 0813
E-mail: steven_suter@ncsu.edu

Mary Tompkins
Immunity to Feline Immunodeficiency Virus
Title: Director, Veterinary Clinical Immunology Laboratory
Phone: 919 513 6255
E-mail: mary_tompkins@ncsu.edu

Sue Tonkonogy
Immune regulation in the gastrointestinal tract
Title: Professor
Phone: 919 513 6252
E-mail: sue_tonkonogy@ncsu.edu

Shweta Trivedi
Veterinary Immunology
Title: Assistant Professor
Phone: 919 515 0266
E-mail: shweta_trivedi@ncsu.edu

Jeffrey Yoder
Characterizations and Function of Innate Immune Response Genes
Title: Associate Professor of Innate Immunology
Phone: 919 515 7406
FAX: 919 515 4237
E-mail: Jeff_Yoder@ncsu.edu
Yoder Lab Web site: ~jayoder

Infectious Diseases

Graduate work in the Infectious Disease Concentration Area includes research at the molecular and cellular level in bacteriology, parasitology, and virology, as well as investigations of the host immune response to these agents. Programs focus on etiology, pathogenesis, diagnostic development, vaccine development, and antimicrobial therapies. Programs also focus on gene regulation and host-pathogen interactions that influence pathogenesis. Research approaches employ a wide variety of molecular, biochemical, pharmacological, and microscopic techniques, utilizing cell culture and whole organisms. Students selecting Infectious Disease will focus on one or more of these areas.

A highly individualized curriculum of study is designed to meet the needs and interests of the student while satisfying selected requirements by the faculty. These include graduate level cell biology and biochemistry, as well as graduate level courses relating to the specific discipline chosen (bacteriology, parasitology, or virology). Additional courses may be chosen by the student and his/her advisor from a large number of college and university offerings.

Students entering the Ph.D. program having completed courses equivalent to the required courses may, with the consent of their thesis committee, petition the concentration area Graduate Committee to waive these requirements.

Courses Required for the Infectious Diseases Concentration

CBS 810 Seminar in Infectious Diseases (1 credit; minimum 3 credits total for doctoral students; minimum 2 credits total for master’s students)

Other Courses

CBS 890 Doctoral Preliminary Exam (1 credit)

CBS 893 Doctoral Supervised Research (variable credit)

CBS 895 Doctoral Dissertation Research

CBS 896 Summer Dissertation Research (variable credit)

CBS 899 Doctoral Dissertation Preparation

 Elective Courses

Elective courses are selected by the student and mentor, and must be approved by the student’s graduate advisory committee. Possible elective course include, but are not limited to, the following:

Biochemistry

BCH 701(Macromolecular Structure; Fall)

BCH 703 (Macromolecular Synthesis and Regulation; Fall)

Microbiology and Immunology

MB 703 (Microbial Diversity; Spring alternate years)

MB 714 (Microbial Metabolic Regulation; Fall)

MB 718 (Introductory Virology; Fall)

MB/IMM 751 (Immunology; Spring)

IMM/TOX 705 (Immunotoxicology; Spring)

IMM/CBS 755 (Immunoparasitology; Spring alternate years)

IMM/CBS/MB/PO 756 (Immunogenetics; Fall alternate years)

IMM/PO 757 (Avian Immunology; Fall alternate years)

IMM/CBS/MB 783 (Adv. Immunology; Fall alternate years)

IMM/CBS 816 (Adv. Top. in Immun. and Biotech.; Fall, Spring, Summer)

CBS 770 (Cell Biology; Fall)

CBS 771 (Vet. Med. Virology II; Fall alternate years)

CBS 774 (Epidemiol. of Inf. Dis. of International Importance; Fall alternate years)

CBS 861 ( Bacterial Pathogenic Mechanisms; Spring alternate years)

Molecular and Cell Biology

GN 701 (Molecular Genetics; Fall)

GN 702 (Cellular and Developmental Genetics; Spring)

GN 710 (Eukaryotic Regulatory Mechanisms; Spring alternate years)

GN 750 (Developmental Genetics; Spring alternate years)

GN/ST 756 (Computations Molecular Evolution; Fall alternate years)

GN/MB 758 (Prokaryotic Molecular Genetics; Spring)

GN/BCH 761 (Adv. Molecular Biology of the Cell; Spring alternate years)

GN/BCH 768 (Nucleic Acids: Structure and Function; Spring alternate years)

GN 810X (Special Topics: Genetics; Spring)

BCH 705 (Molecular Biology of the Cell; Spring)

Statistics

ST 501(Exp. Stats. for Biol. Sci. I; Fall & Spring)

ST 701 (Exp. Stats. for Biol. Sci. II; Fall & Spring)

GN/ST 770 (Statistical Concepts in Genetics; Spring alternate years)

Techniques

BIT 810 (Core Technologies In Molecular and Cellular Biology; Summer)

BIT 815 (Advanced Topics In Biotechnology; Summer)

MB 705 (Biological Scanning Electron Microscopy; Spring)

MB 710 (Biological Transmission Electron Microscopy; on demand)

CBS 732 (Electron Microscopy in Vet. Med.; Spring)

Concentration Area Leader:

Dr. Fred Fuller
Phone: (919) 515- 7396
Fax: (919) 515- 3044
E-mail: fred_fuller@ncsu.edu

Adam Birkenheuer
General Internal Medicine and Infectious Disease
Title: Associate Professor
Phone: 919 513 8288
E-mail: adam_birkenheuer@ncsu.edu

Petra Bizikova
Veterinary Dermatology
Title: Assistant Professor of Dermatology
Phone: 919 515 7395
E-mail: petra_bizikova@ncsu.edu

Ed Breitschwerdt
Detection, characterization, and treatment of canine/feline bacterial pathogens
Title: Professor
Phone: 919 513 8277
E-mail: ed_breitschwerdt@ncsu.edu

Jonathan Fogle
Regulation of Immune Responses to Lentiviruses
Title: Assistant Professor of Immunology
Phone: 919 513 6248
E-mail: jonathan_fogle@ncsu.edu

Isabel Gimeno
Poultry Pathology and Immunology
Title: Associate Professor
Phone: 919 513 6852
E-mail: isabel_gimeno@ncsu.edu

Jody Gookin
Host-pathogen Interactions in the Gut
Title: Associate Professor of Small Animal Internal Medicine
Phone: 919 513 6295
E-mail: jody_gookin@ncsu.edu

Bruce Hammerberg
Allergic Disease
Title: Professor
Phone: 919 513 7712
E-mail: Bruce_Hammerberg@ncsu.edu

Edward Havell
The Innate Anti-bacterial Immune Response
Title: Professor of Immunology
Phone: 919 515 6184
E-mail: ed_havell@ncsu.edu

Paul Hess
Targeted Therapeutics of Immune-mediated Diseases
Title: Assistant Professor of Oncology
Phone: 919 513 6183
E-mail: paul_hess@ncsu.edu

Lola Hudson
Virus infection and Immune Mechanisms of the Brain
Title: Professor
Phone: 919 513 6306
E-mail: lola_hudson@ncsu.edu

Samuel Jones
Regulation of Neutrophil Motility
Title: Professor of Equine Medicine
Phone: 919 513 6200
E-mail: sam_jones@ncsu.edu

Matthew Koci
Avian Immunology
Title: Associate Professor
Phone: 919 515 2626
FAX:
E-mail: MDKoci@ncsu.edu

Scott Laster
Innate Immunity and Inflammation
Title: Professor
Phone: 919 515 7958
FAX: 919 515 7867
E-mail: scott_laster@ncsu.edu

Mike Levy
Immunoparasitology
Title: Professor
Phone: 919 513 8289
FAX: 919 515 3044
E-mail: Mike_Levy@ncsu.edu

Jennifer Miller
Bacterial Pathogenesis and Innate Immunity
Title: Assistant Professor of Microbiology
Phone: 919 515 7867
FAX: 919 515 7867
E-mail: jen_miller@ncsu.edu

Shila Nordone
Regulation of Inflammation
Title: Research Assistant Professor
E-mail: shila_nordone@ncsu.edu

Thierry Olivry
Pathogenesis and Therapy of Pruritis, Atopic Dermatitis and Autoimmune Diseases
Title: Professor of Dermatology
Phone: 919 513 7711
E-mail: thierry_olivry@ncsu.edu

Laura Ott
Inflammation and Biotechnology
Title: Teaching Scholar
Phone: 919 513 7685
E-mail: laura_ott@ncsu.edu

Lauren Schnabel
Stem cell biology and Immunology
Title: Assistant Professor
Phone: 919.515.7410
E-mail: lauren_schnabel@ncsu.edu

Frank Scholle
Viral Immunology
Title: Associate Professor
Phone: 919 513 7574
E-mail: frank_scholle@ncsu.edu

Michael Sikes
Lymphocyte development and differentiation
Title: Associate Professor
Phone: 919 513 0528
E-mail: mike_sikes@ncsu.edu

Steve Suter
Genetics and Therapy of Cancer
Title: Associate Professor of Oncology
Phone: 919 513 0813
E-mail: steven_suter@ncsu.edu

Mary Tompkins
Immunity to Feline Immunodeficiency Virus
Title: Director, Veterinary Clinical Immunology Laboratory
Phone: 919 513 6255
E-mail: mary_tompkins@ncsu.edu

Sue Tonkonogy
Immune regulation in the gastrointestinal tract
Title: Professor
Phone: 919 513 6252
E-mail: sue_tonkonogy@ncsu.edu

Shweta Trivedi
Veterinary Immunology
Title: Assistant Professor
Phone: 919 515 0266
E-mail: shweta_trivedi@ncsu.edu

Jeffrey Yoder
Characterizations and Function of Innate Immune Response Genes
Title: Associate Professor of Innate Immunology
Phone: 919 515 7406
FAX: 919 515 4237
E-mail: Jeff_Yoder@ncsu.edu
Yoder Lab Web site: ~jayoder

Pathology

Graduate work in the Pathology Concentration Area includes research at the molecular and cellular level in infectious disease pathogenesis, oncology, toxicology, hematology, and immunology. Research approaches employ a wide variety of molecular, biochemical, pharmacological, and microscopic techniques, utilizing cell culture and whole organisms. Students selecting Pathology will focus on one or more of these areas.

A highly individualized curriculum of study is designed to meet the needs and interests of the student while satisfying selected requirements by the faculty. These include courses in advanced systemic histopathology, toxicologic pathology, avian pathology, and seminar courses in clinical, necropsy, and surgical pathology. Additional courses may be chosen by the student and his/her advisor from a large number of college and university offerings. An appropriate level of competence in diagnostic pathology must be demonstrated by examination before completion of the graduate program.

Courses Required for the Pathology Concentration

CBS 795 General Pathology (3 credits)

CBS 810 Seminar in Pathology (1 credit; 3 credits total for doctoral students; minimum 2 credits total for master’s students)

Concentration Area Leader:
Dr. Mac Law
Phone: (919) 513- 7411
Fax: (919) 515- 4237
E-mail: mac_law@ncsu.edu

John Barnes
Infectious and non-infectious diseases of avian species
Title: Professor of Poultry Health Management, Pathology
Phone: 919 513 6273
E-mail: john_barnes@ncsu.edu

GARY A. BOORMAN

Title: Adjunct Associate Professor of Pathology
Phone: 1 888 268 2623
E-mail: gary.boorman@covance.com

LUKE BORST

Streptococcal pathogenesis and cancer metabolism
Title: Assistant Professor of Pathology
Phone: 919 513-8287
E-mail: luke_borst@ncsu.edu

John M. Cullen
Biology of hepadnavirus infections and hepadnavirus-induced liver disease
Title: Professor of Anatomic Pathology
Phone: 919 513 6350
E-mail: john_cullen@ncsu.edu

OSCAR FLETCHER

Avian histopathology
Title: Professor of Poultry Health Management
Phone: 919 513-6491
E-mail: oscar_fletcher@ncsu.edu

Marlene Hauck
Targeted therapeutics and hyperthermia clinical trials
Title: Associate Professor of Oncology
Phone: 919 513-6272
E-mail: marlene_hauck@ncsu.edu

DAVID HINTON

Environmental Toxicology
Title: Adjunct Assistant Professor
Phone: 919 613 8038
E-mail: dhinton@duke.edu

Jerry McHugh Law
Aquatic toxicologic pathology
Title: Assistant Professor of Pathology
Phone: 919 515 7411
E-mail: mac_law@ncsu.edu

Keith Linder
Keratinocyte mediated innate host resistance to skin infection
Title: Clinical Associate Professor of Pathology
Phone: 919 513 6257
E-mail: keith_linder@ncsu.edu

DAVID MALARKEY

Title: Adjunct Assistant Professor of Pathology
Phone: 919 541 1745
E-mail: david_malarkey@ncsu.edu

MARK SIMPSON

Title: Adjunct Professor
Phone: 301 435 7176
E-mail: ms43b@nih.gov

STEVE SUTER

Canine and feline lymphoma
Title: Assistant Professor of Oncology
Phone: 919 513-0813
E-mail: steve_suter@ncsu.edu

Pharmacology

Graduate work in the Pharmacology Concentration Area includes research at the molecular and cellular level in pharmacology, pharmacokinetics, drug interactions, drug residues and metabolites, anesthetics and autonomic drugs, pulmonary biology, oncology, ophthalmology, gastroenterology, reproductive endocrinology, and lipid-, peptide-, and oxygen-derived mediators of inflammation. Research approaches employ a wide variety of molecular, biochemical, pharmacological, and microscopic techniques, utilizing cell culture and whole organisms. Students selecting Pharmacology will focus on one or more of these areas.

A highly individualized curriculum of study is designed to meet the needs and interests of the student while satisfying selected requirements by the faculty. These include courses in introductory pharmacology and toxicology, advanced pharmacology, pharmacokinetics, statistics, and participation in a seminar series in pharmacology. Additional courses may be chosen by the student and his/her advisor from a large number of college and university offerings.

Courses Required for the Pharmacology Concentration

CBS 860 Instrumentation in Pharmacological Research (1 credit)

CBS 762 Principles in Pharmacology (3 credits)

CBS 787 Pharmacokinetics (3 credits)

TOX 710 Biochemical Toxicology (3 credits)

CBS 810 Seminar in Pharmacology (1 credit; minimum 3 credits total)

Elective Courses

Other elective courses are approved by the student’s advisory committee. Students requiring foundational courses are encouraged to consider TOX 501 General Toxicology and BCH 451/553 Biochemistry.

Concentration Area Leader:
Dr. Jennifer Davis
Phone: (919) 513-6720
Fax: (919) 515-6717
E-mail: jennifer_davis@ncsu.edu

Ronald Baynes
Title: Associate Professor
Phone: 919 513 6261
E-mail: ronald_baynes@ncsu.ed

James Bonner
Toxicology
Title: Associate Professor
Phone: 919 515 8615
Email: james_bonner@ncsu.edu

JENNIFER DAVIS

Title: Assistant Professor
Phone: 919 513 6720
E-mail: jennifer_davis@ncsu.edu

David Dorman
Title: Professor
Phone: 919 513 – 6237
E-mail: david_dorman@ncsu.edu

Lloyd Fleisher
Roles of cytokines in the initiation and resolution of intraocular inflammation
Title: Professor
Phone: 919 515 4481
E-mail: lloyd_fleisher@ncsu.edu

Brian Gilger
Ophthalmology
Title: Professor
Phone: 919 513 1273
E-mail: brian_gilger@ncsu.edu

TERESA LEAVENS

Title: Research Assistant Professor
Phone: 919 513 6446
E-mail: teresa_leavens@ncsu.edu

Steve Marks
Emergency and critical care medicine, general internal medicine, cardiopulmonary medicine and pain management
Title: Associate Professor
Phone: 919 513 6130
E-mail: steve_marks@ncsu.edu

Christine McGahan
Mechanisms of initiation and treatment of cataract formation
Title: Professor
Phone: 919 515 4482
E-mail: chris_mcgahan@ncsu.edu

Nancy Monteiro-Riviere
Toxicity of environmental and novelpharmaceutical compounds
Title: Professor
Phone: 919 513 6426
E-mail: nancy_monteiro@ncsu.edu

Mark Papich
Clinical pharmacology of drugs in animals
Title: Professor
Phone: 919 513 6221
E-mail: mark_papich@ncsu.edu

Jim Riviere
Quantitative mechanistic models of chemical absorption across skin
Title: Professor
Phone: 919 513 6305
E-mail: jim_riviere@ncsu.edu

Robert Smart
Chemical carcinogenesis and development in model laboratory systems
Title: Professor
Phone: 919 515 7245
E-mail: rcsmart@unity.ncsu.edu
Website: http://www.tox.ncsu.edu/faculty/smart/index.htm

GEOF SMITH

Ruminant Health and Production Medicine
Title: Associate Professor
Phone: 919 513 6288
E-mail: geoffrey_smith@ncsu.edu

Population Medicine

Graduate work in the Population Medicine Concentration Area includes research in epidemiology of a variety of species, medical geography, assessment of management practices on food animal production systems, production medicine for food industries, developing and monitoring systems for health and productivity, computer based record keeping systems, and development of applied statistical and analytic methods. Students selecting Population Medicine will focus on one or more of these areas.

A highly individualized curriculum of study is designed to meet the needs and interests of the student while satisfying selected requirements by the faculty. These include courses in epidemiology, statistics and other quantitative disciplines. Additional courses may be chosen by the student and his/her advisor from a large number of college and university offerings.

Courses Required for the Population Medicine Concentration

ST 512 Experimental statistics for biological sciences II (3 credits)

CBS 580 or UNC EPI 160 or UNC EPI 168 (3 credits)

CBS 580 Clinical Veterinary Epidemiology

EPI 160 Principles of Epidemiology

EPI 168 Fundamentals of Epidemiology

CBS 754 Principles of Analytical Epidemiology (3 credits)

VPH 650 Seminar in Pop Med & Vet Public Health (1 credit; minimum 3 credits total for doctoral students; minimum 2 credits total for master’s students)

Other Courses

CBS 890 Doctoral Preliminary Exam (1 credit)

CBS 893 Doctoral Supervised Research (variable credit)

CBS 895 Doctoral Dissertation Research

CBS 896 Summer Dissertation Research (variable credit)

CBS 899 Doctoral Dissertation Preparation

Other Courses from NC State

CBS760: Molecular Epidemiology of Infectious Diseases of Veterinary and Public Health Importance

CBS 780: Veterinary Production Epidemiology

ST 711: Design of experiments

ST 535: Statistical process control

ST 731: Applied multivariate statistical analysis

ST 505: Applied nonparametric statistics

ST 733: Applied spatial statistics

ST 732: Applied longitudinal data analysis

ST 520: Statistical principles of Clinical Trials and Epidemiology

ST 715: Theory of sampling applied to Survey Design

ST 506: Sampling animal populations

ST 745: Analysis of Survival Data

ST 755: Advanced analysis of variance and variance components

ECG 751: Econometrics

ECG 765 : Mathematical Methods for Economics

ECG 741: Agricultural Production and Supply

ECG 748: Theory of International Trade

Courses taught at UNC School of Public Health Biostatistics or Epidemiology Depts.

Can be used as equivalents to many of the courses noted above.

231 Bayesian Statistics

256 Introduction To Nonparametric Statistics

257 Nonparametric Procedures In Biometric Research

259 Applied Time Series Analysis (3)

260 Advanced Probability And Statistical Inference I & (261) II

262 Generalized Linear Models or

263 Advanced Linear Models

264 Advanced Survey Sampling Methods

265 Linear Models In Categorical Data Analysis (3).

266 Advanced Linear Models

271 Demographic Techniques

280 Theory And Methods For Survival

Concentration Area Leader:
Dr. Sid Thakur
Phone: (919) 513-0729
Fax: (919) 515-3044
E-mail:sthakur@ncsu.edu

Glen Almond
Swine Health & Production
Title: Professor
Phone: 919 513 6370
E-mail: glen_almond@ncsu.edu

Kevin Anderson
Bovine mastitis, detection of antimicrobial residues, improved therapy and diagnosis
Title: Professor
Phone: 919 513 6245
E-mail: kevin_anderson@ncsu.edu

Maria Correa
Disease control and evaluation programs relating to food safety and zoonoses; rabies control

Title: Associate Professor
Phone: 919 513 6253
E-mail: maria_correa@ncsu.edu

Lee-Ann Jaykus
Nucleic acid amplification techniques for detection of bacterial and viral foodborne pathogens

Title: Associate Professor
Phone: 919 515 2971
E-mail: leeann_jaykus@ncsu.edu

Suzanne Kennedy-Stoskopf
Title: Research Associate Professor
Phone: 919 515 8111
E-mail: suzanne_stoskopf@ncsu.edu

Jay Levine
Aquatic animal epidemiology and ecosystem health, microbial communities, and environmental monitoring.

Title: Professor of Epidemiology and Public Health
Phone: 919 513 6397

E-mail: jay_levine@ncsu.edu

David Ley
Pathophysiology of avian mycoplasma infections; development of diagnostics and vaccines
Title: Professor
Phone: 919 513 6269
E-mail: david_ley@ncsu.edu

Barbara Sherman
Title: Clinical Associate Professor
Phone: 919 513 6141
E-mail: barbara_sherman@ncsu.edu

Robert Sills
Title: Adjunct Associate Professor
Phone: 919 541 0180
E-mail: sills@niehs.nih.gov

Michael Stoskopf
Environmental and aquatic animal medicine

Title: Professor
Phone: 919 513 6279
E-mail: michael_stoskopf@ncsu.edu

Sid Thakur
Molecular Epidemiology of Resistant Food Borne Pathogens
Title: Assistant Professor
Phone: 919 513 0729
E-mail: sid_thakur@ncsu.edu

 

Policies and Requirements for the Master’s of Science
Degree

A. Objectives

The Master’s of Science degree in Comparative Biomedical Sciences shall reflect a mastery of the principles of a discipline in Comparative Biomedical Sciences, with students engaging in research in one of the five concentration areas in the Comparative Biomedical Sciences Graduate Program.

B. Formal Requirements for the Doctoral Degree in Comparative Biomedical Sciences

  1. The CBS program director will guide the student in the pursuit of course work and training until the student selects an adviser.
  2. The Master’s of Science degree requires the equivalent of at least 2 academic years of work beyond the baccalaureate degree with a minimum of 36 semester hours of graduate credit, including 18 semester hours of letter-graded graduate credit.
  3. It is required that all first year Comparative Biomedical Sciences Graduate Students enrolled in the master’s program complete the required core curriculum for their concentration area.
  4. All CBS Graduate Students are encouraged to enroll in additional coursework. The student will consult his/her adviser for recommended additional coursework in accordance with the student’s chosen course of study. A list of available electives can be found on the requirements page for each concentration area. Other courses may be added with approval of the CBS Graduate Studies Committee.
  5. All master’s students are encouraged to complete the master’s degree within a three (2) year time period.
  6. All master’s students must successfully complete the Final Oral Examination (Defense of Dissertation) covering the dissertation and related fields of investigation.

C. Final Oral Examination

The Final Oral Examination, two hours in length, will be administered by the student’s advisory committee and a Graduate School Representative, appointed by the graduate school upon approval of the graduate plan of work. Oral presentations are open to the CVM community.

D. Dissertation Final Copy

Students are required to submit an electronic dissertation to the Graduate School through the ETD submission system in the MyPack within 24 hours of receiving an unconditional pass on the final examination.

E.. Additional Graduate School Requirements

All requirements of the Graduate School must be fulfilled in order to schedule the final dissertation defense and to formally complete graduate studies in the program.