NC State Veterinary Hospital offers DNA testing for a variety of canine and feline breed specific genetic mutations resulting in disorders.
We are now offering discounted pricing for litters of two or more! Visit the specific testing page below for more information.
If you would to make an appointment for genetics consultation about your pet or breed issues, or your client’s genetics concerns, please email: firstname.lastname@example.org.
Cardiac Health Testing
Cardiac Pharmacogenetic Testing
Canine ACE Gene Polymorphism
Renin-angiotensin aldosterone system (RAAS), which is the neurohormonal cascade initiated by the release of renin and ending in the stimulation of aldosterone release from the adrenal glands, is activated in dogs with advanced heart disease, and contributes to disease progression and clinical signs.
Gordon Setter: Cerebellar degeneration
Cerebellar degeneration has been documented in the Gordon Setter as an autosomal recessive inherited disorder since at least the 1960s. It causes a progressive loss of coordination resulting in the hallmark ataxic gait characterized by dramatic overstepping, particularly obvious in the forelimbs. Onset of signs ranges from 6 months to 4 years of age and disease progression tends to be slow, occurring over several years.
Boykin Spaniel: SLC12A6 Mutation
A genetic mutation in the gene SLC12A6 associated with motor and sensory neuropathy in Boykin Spaniels has been identified through a partnership between the Olby and Meurs labs at NCSU. The mutation is inherited in a recessive manner and careful breeding practices can be used to remove the prevalence of this disease from the Boykin Spaniel population.
Other Genetic Testing
Rottweiler: LOXHD1 Deafness
A genetic mutation associated with nonsyndromic deafness and hearing loss in Rottweilers has been identified by the Lohi Lab at the University of Helsinki. This mutation is in the gene LOXHD1, which has also been implicated in human hearing disorders. The mutation is thought to be inherited as a recessive trait and careful breeding practices can be used to remove the prevalence of this disease.