NC State College of Veterinary Medicine’s Nanette Nascone-Yoder has been awarded a $1.5 million grant from the National Institutes of Health for a five-year study into the early development of the stomach curvature. Abnormalities in the normal leftward curvature of the stomach have been linked to gastroesophageal reflux disease (GERD), the most prevalent upper gastrointestinal disorder in the Western world.
The project, “Ahead of the Curve: Mechanisms of Left-Right Asymmetric Stomach Morphogenesis,” will be funded through 2023 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, one of the NIH’s research centers.
Nascone-Yoder, CVM associate professor of developmental biology, focuses her research on the cellular and molecular mechanisms behind organs becoming left-right asymmetric, information that’s particularly valuable in understanding certain birth defects.
Nascone-Yoder launched her Digestive Track Development Lab at the CVM in 2006 and has received research funding from the NIH, the National Science Foundation and the American Heart Association. Her lab pioneered the use of a new animal model to study organ development.
A University Faculty Scholar, Nascone-Yoder holds a Ph.D. in cell and developmental biology from Harvard University.
For more information on the Digestive Track Development Lab, go here.
For more information on the CVM’s Department of Molecular Biomedical Sciences, go here.