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Clinical Trials

Clinical research is an important mechanism of increasing medical knowledge, advancing veterinary practice, and improving animal health by bringing the very newest medical discoveries to the patient as soon as safely possible.

The North Carolina State University College of Veterinary Medicine routinely participates in clinical trials that involve a wide range of diseases. Our studies are open to current patients of the Veterinary Hospital as well as new patients. We are continually beginning new clinical trials and recruiting patients for upcoming trials.

TREATMENT OF CANINE OSTEOSARCOMA WITH PERCUTANEOUS CEMENTOPLASTY AND PALLIATIVE RADIATION THERAPY

 

  • Principle Investigator: Marine Traverson
  • NC State University College of Veterinary Medicine is looking for dogs with appendicular osteosarcoma of any long bone. The goal of this pilot clinical trial is to offer a minimally invasive limb-sparing treatment option as an alternative to limb amputation. Patients will receive percutaneous cementoplasty (PC). PC involves the injection of a special cement into the bone tumor. The cement will strengthen and support the bone, providing pain relief and increased mobility. Patients will also receive palliative radiation therapy.
  • Patients will be required to come to NCSU for treatment. Owners must be complaint with study visits, and be willing to complete the questionnaires. In addition to routine diagnostics and treatments, we will also be performing gait analysis and sensory testing at each visit. Initial treatment will last 1 week (M-F). Follow-up visits will occur every month for 3 months, then every 3 months for a total of 1 year.
  • Contact:  Clinical Studies Core: 919-513-6453 OR cvmclinicalstudies@ncsu.edu

Translational Medicine Page

Equine amniotic membrane allografts increase granulation tissue production while maintaining appropriate wound healing, according to a study published in Veterinary Surgery.

The research explores growth factors in the allografts and evaluates the effect on distal limb wound healing in horses. The allografts are likely to be most beneficial in treating substantial wounds when production of large amounts of granulation tissue is needed.

Lower leg wounds are common in horses and often extensive, leading to longer repair times and higher risk of infection. Study authors include Lauren Schnabel, Timo Prange, Jennifer Gilbertie and Alex Fowler.

**Found in September Research Roundup

TCR-yδ T cells play a crucial role a pig’s lymphatic system response to porcine reproductive and respiratory syndrome virus, or PRRSV, according to new research published in Viruses.

PRRSV leads to reproductive failure in breeding pigs and causes respiratory illness in young pigs. Though PRRSV vaccines are available, most struggle to protect against the plethora of PRRSV strains. By analyzing T-cell response to type-2 PRRSV, the study offers valuable information for improving PRRSV vaccine development.

The study’s authors include Tobias Kaeser, Glen Almond, Elena Crisci and Jonathan Fogle.

Click on the links below to browse trials by species or by service: