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Clinical Trials

Clinical research is an important mechanism of increasing medical knowledge, advancing veterinary practice, and improving animal health by bringing the very newest medical discoveries to the patient as soon as safely possible.

The North Carolina State University College of Veterinary Medicine routinely participates in clinical trials that involve a wide range of diseases. Our studies are open to current patients of the Veterinary Hospital as well as new patients. We are continually beginning new clinical trials and recruiting patients for upcoming trials.


  • Principal Karen Tefft
  • Evaluating the efficacy of a new diet specially formulated to dissolve struvite stones in the bladders of cats. Struvite stones are among the most common types of bladder stones that can form in cats. They can cause irritation and pain and can lead to blood in the urine and possible obstruction of the urethra (the urine outflow tract). Standard treatment is to either remove them surgically or dissolve them by altering the pH and other characteristics of the cat’s urine. This is done through medications or by exclusively feeding a diet that is specially formulated to promote stone dissolution. Most struvite stones can be dissolved in 1 – 3 months with strict dietary compliance.
  • In this study, cats with suspected struvite stones will be provided with a nutritionally balanced and complete test diet. They will be monitored every 2 weeks for radiographic evidence of stone dissolution. In addition, acceptance of the diet and weight will also be monitored. For cats that fail to have stone dissolution occur after 56 days on the test diet, a cystotomy will be performed and the stones sent out for analysis.
  • Contact: Karen Tefft: 919-513-6670 OR

Click on the links below to browse trials by species or by service: