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Translational Medicine

At the North Carolina State University College of Medicine, we move our research from the bench to the patient. Our researchers span a number of research strengths including regenerative medicine, infectious disease, biological barriers, genetics, neurosciences and computational research.

 

 

 

 

Some of our bench to patient work has included the following studies:

 

• The use of the pig model is contributing greatly to the understanding of several human medical conditions and can prove beneficial in studying male and female human sexually transmitted infections (STI), according to a study co-authored by Tobias Kaeser.

There has been growing success in using the pig as an experimental model for human medicine, in large part due to similarities in anatomy, genetics, immunology and physiology to humans. The new study outlines ways a porcine model can play a crucial role in STI research, including studies on chlamydia, herpes and HPV. Infection, Genetics and Evolution published the study.

* Found on the Jan 2019 research roundup

 

• A study co-authored by Duncan Lascelles investigates gene expression signatures in nervous system tissue from cats with degenerative joint disease, offering possible insight into ways to target and treat chronic pain in animals and humans.

Investigating differences in gene expression between normal and well-defined disease states is one approach to understanding the neurology of pain, and the neurobiology of feline DJD pain is a complete mystery.

The research results, published in the Veterinary Journal, point out increased expression of genes in DJD-affected cats considered to be involved in neuropathic pain. Such studies may lead to pinpointing relevant targets to control chronic pain.

* Found on the December 2018 research roundup.