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Translational Medicine

At the North Carolina State University College of Medicine, we move our research from the bench to the patient. Our researchers span a number of research strengths including regenerative medicine, infectious disease, biological barriers, genetics, neurosciences and computational research.

Some of our bench to patient work has included the following studies:

• Equine amniotic membrane allografts increase granulation tissue production while maintaining appropriate wound healing, according to a study published in Veterinary Surgery.

The research explores growth factors in the allografts and evaluates the effect on distal limb wound healing in horses. The allografts are likely to be most beneficial in treating substantial wounds when production of large amounts of granulation tissue is needed.

Lower leg wounds are common in horses and often extensive, leading to longer repair times and higher risk of infection. Study authors include Lauren Schnabel, Timo Prange, Jennifer Gilbertie and Alex Fowler.

**Found in September Research Roundup

• TCR-yδ T cells play a crucial role a pig’s lymphatic system response to porcine reproductive and respiratory syndrome virus, or PRRSV, according to new research published in Viruses.

PRRSV leads to reproductive failure in breeding pigs and causes respiratory illness in young pigs. Though PRRSV vaccines are available, most struggle to protect against the plethora of PRRSV strains. By analyzing T-cell response to type-2 PRRSV, the study offers valuable information for improving PRRSV vaccine development.

The study’s authors include Tobias Kaeser, Glen Almond, Elena Crisci and Jonathan Fogle.