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September CVM Research Roundup

A look at some of the newest published studies coming out of the NC State College of Veterinary Medicine.

  • A rare blood sample from a North Atlantic right whale was used in a new study that maps the mitochondrial genome sequence of the endangered species. Co-authored by the CVM’s Julia Allwood, Melissa Scheible and Seth Faith and published by the journal Conservation Genetics Resources, the work represents an large improvement in sequence depth compared to standard DNA extraction. The North Atlantic right whale was the final species of three within the Eubalaena genus to have its mitochondrial genome sequenced. Read the study here.

    The app, WhaleScale, is available on iTunes.

  • Craig Harms has helped created an app to calculate the estimated weights of cetaceans based on length, particularly useful in managing stranding events. The app, WhaleScale, is available on iTunes.
  • Harms is also the co-author of the newly released “Sea Turtle and Rehabilitation” textbook, described as, “the first-ever comprehensive book on sea turtle husbandry, health, medicine and surgery.” Read more about the book here.
  • A study from Sid Thakur, appearing in the journal Applied and Environmental Microbiology, characterizes antimicrobial resistance determinants in Salmonella samples collected from commercial swine farms after manure application. The study details how antimicrobial resistance is released into the environment through the common practice of spreading manure around farms. Read the study here.
  • Researchers, including study co-author Thierry Olivry, have studied how to process poultry to make it hypoallergenic for animals with allergies to eat. The study, published in BMC Veterinary Research, found that extensive protein hydrolyzation is indispensable in preventing an immunoglobulin E-mediated poultry allergen response in dogs and cats. The work will help make certain diets safer for companion animals with food allergies. Read the study here.
  • CVM clinical researchers have identified a new virus in horses that causes skin lesions. The study, published in Veterinary Dermatology and co-authored by Keith Linder, Petra Bizikova, Jennifer Luff and Betta Breuhaus, describes a novel equine papillomavirus that can cause dermatologic lesions lasting for more than one year. Read the study here.

H. naledi teeth in mandible. Image by Alice MacGregor Harvey/NC State Veterinary Medicine

  • Research co-authored by Christopher Walker shows that tooth development of the new hominin species Homo naledi is more similar to humans than chimpanzees. The study, published in Biology Letters, analyzed tooth formation and eruption in two developing dentitions of H. naledi, a late-surviving, morphologically mosaic species. Deciduous dental development was more humanlike, while later stages of tooth development showed a mix of human- and chimpanzee-like patterns. Read the study here.
  • A CVM study evaluates a unique anesthetic agent for loggerhead sea turtles. Co-authored by Lysa Posner, Greg Lewbart and Craig Harms, the research explored the effects of alfaxalone on yearling loggerhead sea turtles at three different doses in an attempt to standardized dosage and other protocols. The work was published in the Journal of the American Veterinary Medical Association.
    Read the study here.
  • A new research collaboration between the CVM and Duke University uses radiofrequency ablation to better understand esophageal injury and repair. Researchers, including co-authors Leandi Kruger, Liara Gonzalez, Tiffany Pridgen, Gwendolyn Carnighan, developed a novel porcine model to study repair in an animal esophageal submucosal glands, which has strong translational applications for humans suffering from a range of esophageal diseases. The findings were published in the American Journal of Physiology – Gastrointestinal and Liver Physiology.
    Read the study here.