Internal Medicine

Apr 12, 2024

Now Recruiting Dogs with Babesia gibsoni

Principle Investigator Dr. Birkenheuer Description NC State College of Veterinary Medicine is enrolling dogs with Babesia gibsoni in a trial to evaluate if the use of a new drug combination (atovaquone/proguanil hydrochloride, azithromycin, and artemisinin) can improve treatment outcomes. A new treatment regimen using atovaquone/proguanil hydrochloride, azithromycin, and an artemisinin derivative has recently been shown to… 

Oct 20, 2023

Now Enrolling Dogs with Invasive Bladder Cancer

Principle Investigator Dr. Paul Hess Description NC State Medical Oncology is enrolling patients for a clinical trial of an experimental immunotherapy for the treatment of bladder cancer. The primary purpose of this study is to investigate the safety and immune-stimulating properties of a novel therapy being developed at NCSU. Testing Requirements 8-day study (Monday – Monday)… 

Jul 18, 2023

Now Enrolling Canine Patients with Liver Tumors

Principle Investigator Dr. Kyle Mathews Description Does your dog have a liver tumor? We are now enrolling canine patients that have a liver tumor into a clinical trial that is using a new therapy called INSPIRE, which uses electrical pulses to safely destroy the cells within a tumor. This study has two treatment groups. One… 

May 12, 2023

Osteoarthritis Oral Microbiome Analysis in Cats

Principal Investigator Jody Gookin Description A one-time saliva sample from your cat to analyze their oral microbiome (the microbial composition of their mouths.) The analysis will allow us to identify patterns associated with the presence or absence of certain diseases. Testing Requirements A one-time visit to NCSU for a physical examination and saliva sample. There… 

Jan 31, 2023

Screening urine samples from high-risk dog breeds for early bladder cancer

Principal Investigator Dr Shelly Vaden Description This study is screening urine samples from clinically healthy dogs at increased risk of bladder cancer, to determine if they test positive for a genetic marker of the disease (a specific mutation in the dog BRAF gene). The goal is to determine whether this BRAF Mutation Detection test can… 

Jan 31, 2023

Therapeutic trials for canine bladder cancer

Principal Investigator Dr Shelly Vaden Description This study will investigate whether the administration of a dietary supplement slows the progression of canine bladder cancer (also known as transitional cell carcinoma/urothelial carcinoma, or TCC/UC) in dogs treated with standard of care therapy Testing Requirements Participants will be asked to: – bring their dog for an initial… 

Jan 19, 2023

Now Enrolling Dogs with Bladder Cancer

Principal Investigator Dr. Michael Mastromauro Description NC State University College of Veterinary Medicine is enrolling in a clinical trial to investigate if a probiotic can improve cancer care and outcomes in dogs with bladder cancer. This is a placebo-controlled study, not all dogs will receive the probiotic, but all dogs will receivechemotherapy (vinblastine/piroxicam). Testing Requirements Dogs… 

Aug 3, 2022

MEDICAL RESOLUTION OF GALLBLADDER MUCOCELE FORMATION IN DOGS

Principal Investigator Jody Gookin Testing Requirements – Exclusive feeding of Royal Canin Gastrointestinal Low Fat dry or canned food with a 10% snack allowance for up to 1 year (paid for by study). Your dog’s feeding plan will be prescribed and monitored by a veterinary nutritionist. – Oral administration of up to 15 capsules of… 

Aug 3, 2022

GI Lymphoma/IBD Oral Microbiome Analysis

Principal Investigator Jody Gookin Description A one-time saliva sample from your cat to analyze their oral microbiome (the microbial composition of their mouths). The analysis will allow us to identify patterns associated with the presence or absence of certain diseases. $50 electronic gift card for participation Testing Requirements One-time saliva sample Enrollment Start 03/01/2022 Enrollment… 

Aug 3, 2022

Osteoarthritis Oral Microbiome Analysis in Dogs

Principal Investigator Jody Gookin Description A one-time saliva sample from your dog to analyze their oral microbiome (the microbial composition of their mouths). The analysis will allow us to identify patterns associated with the presence or absence of certain diseases. Testing Requirements A one-time visit to NCSU for a physical exam and  saliva sample.  There…