October 25, 2017
Stuck on you: Nanogel capsule helps cardiac stem cells stay in place
Cardiac stem cell therapy is a promising treatment for damaged hearts. However, researchers are still working on two major issues with the therapy – how to keep the stem cells in place and how to prevent rejection when the stem cells are not from the patient’s own body. A new approach from NC State researcher
January 3, 2017
Synthetic Stem Cells Could Offer Therapeutic Benefits, Reduced Risks
Stem cell therapies work by promoting endogenous repair; that is, they aid damaged tissue in repairing itself by secreting “paracrine factors,” including proteins and genetic...
December 14, 2016
Cheng, Ghashghaei Selected as University Faculty Scholars
Launched in 2012, the annual University Faculty Scholars program honors “top early- and mid-career faculty who are pursuing research to solve society’s most pressing...
June 28, 2016
New Way Out: Researchers Show How Stem Cells Exit Bloodstream
This process, dubbed angiopellosis by the researchers, has implications for improving our understanding of not only intravenous stem cell therapies...
September 11, 2015
Spheroid Stem Cell Production Sows Hope for IPF Treatment
Instead of attempting to isolate and sort individual lung stem cells or genetically convert other types of cells into lung stem cells, Cheng used a multicellular spheroid method to harvest and grow them. A spheroid is a three-dimensional cellular structure that has...
March 12, 2015
Heart of the Matter: Veterinary Research and America’s Heart Disease Burden
From a comparative medicine standpoint, animals are critical for our understanding of cardiac diseases such as atherosclerosis, dilated cardiomyopathy, or congenital cardiac disorders. Dogs and cats are natural...
October 2, 2014
New Nanomedicine Improves Stem Cell Therapy, May Help Regenerate Healthy Heart Tissue
MagBICE engaging therapeutic stem cells with injured cardiomyocytes, Illustration by Alice Harvey. A targeted nanoparticle created by researchers at North Carolina State University and the Cedars-Sinai Heart Institute may help heart attack patients regenerate healthy heart tissue without using donated or processed stem cells. This new nanomedicine could also alleviate some of the difficulties involved
August 18, 2014
A Conversation with Ke Cheng, NC State University Professor of Regenerative Medicine
The ability to regenerate human tissues and organs once considered a futuristic possibility today is a fast growing medical specialty and the focus of one of the investigative cores at North Carolina State University’s Center for Comparative Medicine and Translational Research. Regenerative Medicine—the process of replacing or regenerating cells, tissues or organs to restore or
August 18, 2014
Researcher Repairs Damaged Heart Tissue with Adult Stem Cells
Stem cell therapy is a promising option for repairing heart tissue damaged by heart attack. However, the main obstacle to cardiac stem cell therapy also happens to be pretty difficult to get around – and that’s the fact that the heart is constantly in motion. “Cell retention is always problematic when you do cell transplantation,
December 9, 2013
Chancellor’s Faculty Excellence Program at NC State Includes a Regenerative Medicine Component
The ability to regenerate human cells, tissues, and organs was once considered a futuristic possibility but today regenerative medicine is a fast growing medical specialty and the focus of one of the investigative cores at North Carolina State University’s Center for Comparative Medicine and Translational Research. Seven years ago the then new field was described