Neurology

Nov 9, 2023

Riluzole as a Neuroprotectant in Canine Degenerative Myelopathy

Principle Investigator Dr Natasha Olby Description This study will evaluate the effect of Riluzole, a drug already FDA-approved for the treatment of human ALS, on the progression of clinical signs in dogs with degenerative myelopathy (DM). This therapy has been previously tested for safety in dogs. The study will be randomized and blinded. This means… 

Oct 16, 2023

New Research Study for Senior Dogs: Targeting Frailty To Improve Healthspan and Well-Being

Principle Investigators Dr. Margaret Gruen Dr. Natasha Olby Co-Investigator Dr. David Knazovicky Description The goal of this study is to monitor how frailty in senior dogs progresses over time, and how activity impacts their well-being. We hope to use what we learn to better treat senior dogs in the future. After the initial screening and… 

Jan 18, 2023

Using the Chiari-like Malformation & Syringomyelia Evaluation (CHASE) Questionnaire* to Assess the Safety & Efficacy of a Novel Pain Management Product in Dogs

Principal Investigator Natasha Olby Description The goals of this study are to evaluate a newly developed questionnaire to assess pain and clinical signs associated with CM/SM in dogs and to evaluate how well a novel veterinary pain management product might treat the condition. Dogs with signs of CM/SM dogs will visit NC State Veterinary hospital for… 

Sep 26, 2022

THE EFFECT OF A NEW COMBINATION OF DIETARY SUPPLEMENTS ON ACTIVITY AND ATTENTION IN AGING DOGS

Description The Canine Neuro-aging Program at NC State College of Veterinary Medicine is recruiting dogs 10 years of age and older to participate in a study on a combination of anti-aging supplements aimed to improve cognitive function, mobility, and quality of life in older dogs. The basis for this study is rooted in our desire to… 

Aug 3, 2022

LONGITUDINAL STUDY OF NEURO-AGING IN DOGS

Principal Investigator Natasha Olby Description Canine Cognitive Dysfunction is an age-related neurobehavioral condition that shares similar features to Alzheimer’s disease observed in humans. The progression of this devastating disease ultimately leads to the decline in cognitive function, severely affecting comfort of life for dogs and their owners. The purpose of this study is to track… 

Aug 2, 2022

FUNCTIONAL CONNECTIVITY MRI IN DOGS WITH IDIOPATHIC EPILEPSY

Principal Investigator Karen Munana Description We are recruiting dogs with idiopathic epilepsy that have experienced at least 2 seizures and are not on antiseizure medications. Dogs that qualify will receive a brain MRI and spinal tap free of charge. For additional details, see: Epilepsy functional MRI Testing Requirements None Enrollment Start 06/01/2022 Enrollment Finish 12/31/2024…