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clinical_trial

Sep 16, 2022

TRAUMA DOGS

NC State Veterinary Hospital is recruiting severely injured dogs or dogs with acute intra-abdominal hemorrhage from intra-abdominal masses, for enrollment in a clinical trial testing a clot-stabilizing drug called tranexamic acid (TXA). Background In humans, early administration of TXA following trauma significantly reduces mortality and risk of death from hemorrhage. Normally, blood clotting is a delicate… 

Aug 3, 2022

NEW TREATMENT FOR IDIOPATHIC CYSTITIS AND CHRONIC URETHRAL OBSTRUCTIONS IN CATS

Principle Investigator Allison Kendall Testing Requirements As an alternative to euthanasia. the clinical trial will test low-dose radiotherapy which is intended to reduce symptoms. -cats will be required to stay at the hospital for 4-5 days during their initial visit for treatment and observation -owners will complete questionnaires at each visit and every 30 days… 

Aug 3, 2022

TRILOGY: A NON-SURGICAL OPTION FOR CANINE SOFT TISSUE SARCOMA (STS)

Principle Investigator Michael W. Nolan Description NC State University College of Veterinary Medicine is looking for dogs diagnosed with soft tissue sarcoma for a new clinical trial evaluating ultrasound-mediated tumor oxygenation. This minimally invasive technology will deliver oxygen to tumor tissue during radiation treatment. This will enhance tumor radiation sensitivity and may increase tumor response. Testing… 

Aug 3, 2022

IS GUT DYSBIOSIS ASSOCIATED WITH CANINE IDIOPATHIC EPILEPSY?

Principle Investigator Karen Munana Description The Companion Animal Epilepsy Research program at NC State University College of Veterinary Medicine is recruiting for a new clinical trial to determine whether dogs with idiopathic epilepsy have alterations in their gut microbial population. Our study team is looking for households with an epileptic dog and an unaffected dog to… 

Aug 3, 2022

LONGITUDINAL STUDY OF NEURO-AGING IN DOGS

Principle Investigator Natasha Olby Description Canine Cognitive Dysfunction is an age-related neurobehavioral condition that shares similar features to Alzheimer’s disease observed in humans. The progression of this devastating disease ultimately leads to the decline in cognitive function, severely affecting comfort of life for dogs and their owners. The purpose of this study is to track… 

Aug 3, 2022

EARLY INTERVENTION FOR DOBERMAN PINSCHERS AT RISK OF DEVELOPING DILATED CARDIOMYOPATHY

Principle Investigator Kathryn Meurs Description We recently identified a genetic mutation in the Titin gene as a common cause of fatal dilated cardiomyopathy in the Doberman pinscher. Dogs that develop the disease frequently die of the disease either from refractory congestive heart failure or sudden cardiac death. Previous studies have demonstrated that medical intervention of… 

Aug 3, 2022

DOGS DIAGNOSED WITH PRIMARY SPONTANEOUS PNEUMOTHORAX

Principle Investigator Valery Scharf Description NC State University College of Veterinary Medicine is evaluating the feasibility of thoracoscopy (minimally invasive surgery) for the identification and localization of pulmonary bullae associated with spontaneous pneumothorax. The current approach to this disease is open surgical exploration via a median sternotomy; by demonstrating the ability of thoracoscopy to identify pulmonary… 

Aug 3, 2022

CLINICAL TRIAL FOR YOUNG DOGS (UNDER 4 YEARS OLD) WITH ARTHRITIS

Principle Investigator Duncan Lascelles Testing Requirements Dogs will take part in a standard set of treatments including study drug, nutritional supplement, and exercise regimen. Patients will be required to come to NCSU for 5 study visits over 4 months, and owners must be willing to complete questionnaires and give their dog oral medications. Dogs will… 

Aug 3, 2022

CLINICAL TRIAL FOR DOGS WITH PRIMARY ANGLE CLOSURE GLAUCOMA

Principle Investigator Hans Westermeyer Testing Requirements Your dog will receive an exam from the NC State Ophthalmology Service 1 month after study enrollment and once every 3 months thereafter. Each visit will include: sedation, a complete ophthalmic exam, photography and ultrasound of the eye’s drainage apparatus, retinal thickness measurement, and quantitative pupillary light reflex evaluation. A… 

Aug 3, 2022

RECRUITING DOGS WITH NATURALLY OCCURRING PULMONARY HYPERTENSION

Principle Investigator Teresa DeFrancesco Description – One all-day visit – Focused echocardiogram – Bloodwork Testing Requirements None Enrollment Start 03/01/2021 Enrollment Finish 05/04/2024 Eligibility – Must weigh 11 pounds (5kg) or more – Receiving sildenafil for 3 or more days and still having clinically significant pulmonary hypertension Flyer View Contact Dr. Terri DeFrancesco: tdefranc@ncsu.edu Dr.…