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clinical_trial

Oct 3, 2023

Assessment of Hindlimb Function & Perfusion after Transcatheter PDA Occlusion

Principle Investigator Dr. Kursten Pierce Description Each patient undergoing transcatheter PDA occlusion will be assigned to either the femoral artery ligation group or the femoral artery repair group. Both methods have been described in literature and applied in practice as standard of care. Femoral artery repair will be performed by an experienced cardiology interventionalist to… 

Sep 28, 2023

Enrolling Dogs With Stifle or Hip Osteoarthritis on a Study Involving LIBRELA

Principle Investigator Masataka Enomoto, B. Duncan X. Lascelles Description Translational Research in Pain team is seeking dogs with osteoarthritis to take part in a study aiming to compare the efficacy of two FDA-approved medications. We will do this using computerized analysis of gait. Enrolled dogs will all receive one of the FDA approved drugs. (Half… 

Aug 3, 2023

Immunotherapy Clinical Trial for Patients with Oral Melanoma

Principal Investigator Dr. Michael Nolan Description NC State Veterinary Hospital is now recruiting dogs with oral malignant melanoma to evaluate the safety, tolerability, and efficacy of a novel immunotherapy. The immunotherapy is an antibody that aims to invigorate your dog’s immune system and help it eliminate cancer cells. Study Requirements Follow-up: After your screening appointment, you… 

Jul 18, 2023

Now Enrolling Canine Patients with Liver Tumors

Principle Investigator Dr. Kyle Mathews Description Does your dog have a liver tumor? We are now enrolling canine patients that have a liver tumor into a clinical trial that is using a new therapy called INSPIRE, which uses electrical pulses to safely destroy the cells within a tumor. This study has two treatment groups. One… 

May 12, 2023

Osteoarthritis Oral Microbiome Analysis in Cats

Principal Investigator Jody Gookin Description A one-time saliva sample from your cat to analyze their oral microbiome (the microbial composition of their mouths.) The analysis will allow us to identify patterns associated with the presence or absence of certain diseases. Testing Requirements A one-time visit to NCSU for a physical examination and saliva sample. There… 

Feb 2, 2023

THE IMPACT OF GI HEALTH ON JOINTS: A CLINICAL STUDY

Principal Investigator Duncan Lascelles Description We are excited to update you on the progress of our clinical study. Due to overwhelming interest and participation, we have temporarily paused enrollment to ensure the highest quality of care and attention to each participant. We anticipate resuming enrollment in late July and encourage you to stay tuned for… 

Jan 31, 2023

Screening urine samples from high-risk dog breeds for early bladder cancer

Principal Investigator Dr Shelly Vaden Description This study is screening urine samples from clinically healthy dogs at increased risk of bladder cancer, to determine if they test positive for a genetic marker of the disease (a specific mutation in the dog BRAF gene). The goal is to determine whether this BRAF Mutation Detection test can… 

Jan 31, 2023

Therapeutic trials for canine bladder cancer

Principal Investigator Dr Shelly Vaden Description This study will investigate whether the administration of a dietary supplement slows the progression of canine bladder cancer (also known as transitional cell carcinoma/urothelial carcinoma, or TCC/UC) in dogs treated with standard of care therapy Testing Requirements Participants will be asked to: – bring their dog for an initial… 

Jan 19, 2023

Now Enrolling Dogs with Bladder Cancer

Principal Investigator Dr. Michael Mastromauro Description NC State University College of Veterinary Medicine is enrolling in a clinical trial to investigate if a probiotic can improve cancer care and outcomes in dogs with bladder cancer. This is a placebo-controlled study, not all dogs will receive the probiotic, but all dogs will receivechemotherapy (vinblastine/piroxicam). Testing Requirements Dogs… 

Jan 18, 2023

Using the Chiari-like Malformation & Syringomyelia Evaluation (CHASE) Questionnaire* to Assess the Safety & Efficacy of a Novel Pain Management Product in Dogs

Principal Investigator Natasha Olby Description The goals of this study are to evaluate a newly developed questionnaire to assess pain and clinical signs associated with CM/SM in dogs and to evaluate how well a novel veterinary pain management product might treat the condition. Dogs with signs of CM/SM dogs will visit NC State Veterinary hospital for…