Cats

Mar 18, 2025

Cats with Hypertrophic Cardiomyopathy: The HALT HCM Study

Principle Investigator Sandra Tou Description This is a blinded, randomized, placebo-controlled clinical field study to provide substantial evidence of effectiveness of a disease modifying drug intervention in the management of ventricular hypertrophy in cats with subclinical Hypertrophic Cardiomyopathy (HCM). The study will consist of up to a 14-day screening period, followed by a 12-month once-weekly…

Feb 17, 2025

Effect of Iron Supplementation on the response to Varenzin-CA1 in Cats with CKD and Anemia

Principle Investigators Autumn N. Harris and Shelly Vaden Description Anemia is common in feline chronic kidney disease (CKD) and several options are available for treatment including the medication Varenzin CA-1 ® . Iron supplementation is an important part of the treatment of anemia in some patients with CKD and is given as standard of care…

Nov 21, 2024

A Blinded, Randomized, and Placebo-Controlled Clinical Trial of a Novel Veterinary Product for the Management of Chronic Kidney Disease in Cats

Principle Investigator Dr. Autumn Harris Description Evidence exists to suggest that aging of the kidney may contribute to the onset and progression of chronic kidney disease (CKD). Rapamycin is a drug that is a known modulator of the aging process and additionally may decrease the formation of fibrosis (scarring) in the kidney. A feline formulation…

Aug 28, 2024

Ammonia Excretion, A Novel Biomarker and Therapeutic Target for Feline CKD

Principle Investigator Dr. Harris Description Chronic Kidney Disease (CKD) is defined as the presence of functional abnormalities in one or both kidneys over a prolonged period of time. Serum creatinine is currently used as a marker of kidney function, but it cannot detect early changes in kidney function. Detecting CKD early has significant importance because…

Jun 3, 2024

Feline Congestive Heart Failure and Coagulation

Principle Investigator Teresa DeFrancesco Description Cats with congestive heart failure (abnormal fluid accumulation) are at high risk for developing blood clots but the risk appears to differ with the manifestation of heart failure. There are two different manifestations of congestive heart failure in cats: 1) primarily pulmonary edema, and 2) primarily pleural effusion. Pulmonary edema…

Apr 3, 2024

Enrolling Cats with Oral Squamous Cell Carcinoma

Principle Investigator Dr. Nolan Description **Currently enrolling for Phase 2** NC State College of Veterinary Medicine is recruiting cats with oral squamous cell carcinoma (SCC) for a new clinical trial. The purpose is to evaluate a new drug meant to enhance standard radiation therapy (RT). All cats will be treated with a standard course of…