Dogs

Mar 13, 2025

Now Recruiting Dogs with Acute Blindness Suspected to be Due to Optic Neuritis

Principle Investigator Dr Annie Oh Description Ophthalmology at NC State College of Veterinary Medicine is enrolling in a clinical study to measure VEPs (visual evoked potentials) and RNFL (retinal nerve fiber layer) thickness in dogs within 2 weeks of the onset of acute optic neuritis. The goal is to assess whether the presence or absence…

Mar 6, 2025

Now Recruiting Dogs with Bone Cancer

Principle Investigator Dr. Nolan Description NC State is recruiting dogs with bone cancer (osteosarcoma) for a clinical trial that compares 2 radiotherapy approaches. Each enrolled dog will get a singledose of radiotherapy, followed within 3 weeks by standard surgery (limb amputation). Testing Requirements Large or giant breed dogs may be eligible if they have:– X-rays…

Jan 6, 2025

Research Study for Senior Dogs: Targeting Frailty To Improve Healthspan and Well-Being

Description Over the past decade, there has been an increased interest in assessing frailty in our aging companion animals. The goal of this study is to monitor how frailty in senior dogs progresses over time, and how activity impacts their well-being. We hope to use what we learn to better care for our aging four…

Aug 28, 2024

Novel Biomarker and Therapeutic Target for CKD in Dogs

Principle Investigator Dr. Harris Description Chronic Kidney Disease (CKD) is defined as the presence of functional abnormalities in one or both kidneys over a prolonged period of time. Serum creatinine is currently used as a marker of kidney function, but it cannot detect early changes in kidney function. Detecting CKD early has significant importance because…

Jul 11, 2024

Dogs with Non-Seasonal Atopic Dermatitis

Principle Investigator Ina Herrmann Description This study is looking for dogs that have non-seasonal atopic dermatitis for a trial to investigate a novel injectable medication similar to Xolair®/Omalizumab with the potential to control the disease for weeks to months. The goal of this study is to reduce the need for daily medications and improving the…

Jul 8, 2024

Pulse Therapy with Clorazepate or Levetiracetam for Cluster Seizures

Principle Investigator Dr. Karen Munana Description We are seeking dogs with idiopathic epilepsy that experience cluster seizures for a new study led by Drs. Karen Muñana and Alejandra Mondino, evaluating pulse therapy for the in-home treatment of cluster seizures. This study is funded by the AKC-Canine Health Foundation. Dogs will be recruited based on the…

Jun 19, 2024

The Pathogenesis of Immune-Mediated Hemolytic Anemia (IMHA)

Principle Investigator Erika Gruber Description NC State University College of Veterinary Medicine is looking for IMHA patients for a blood sample study. The purpose of this project is to investigate whether a key pathway that inhibits phagocytosis (cell ingestion) contributes to IMHA pathogenesis. CD47 (“don’t eat me” signal) is a marker of “self” that negatively…

May 29, 2024

Oral rapamycin for Severe Subvalvular Aortic Stenosis (SAS) in Dogs

Principle Investigator Kursten Pierce Description The purpose of this study is to evaluate whether three times weekly dosing with oral rapamycin can reverse the heart muscle changes associated with subvalvular aortic stenosis (SAS) in dogs. Dogs will undergo an initial screening for eligibility. If your dog enrolls, they will be randomized to receive either low…

May 13, 2024

Paws and Perception: How Human and Dog Factors Shape Behavior

Description There are many potential factors that may influence a dog’s behavior. NC State University College of Veterinary Medicine Thinking Pets Program is now enrolling dogs and their owners for a new research study exploring dog and human factors that may influence dog behavior. We hope to use what we learn to improve how we…

Apr 12, 2024

Now Recruiting Dogs with Babesia gibsoni

Principle Investigator Dr. Birkenheuer Description NC State College of Veterinary Medicine is enrolling dogs with Babesia gibsoni in a trial to evaluate if the use of a new drug combination (atovaquone/proguanil hydrochloride, azithromycin, and artemisinin) can improve treatment outcomes. A new treatment regimen using atovaquone/proguanil hydrochloride, azithromycin, and an artemisinin derivative has recently been shown…