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Dogs

May 29, 2024

Oral rapamycin for Severe Subvalvular Aortic Stenosis (SAS) in Dogs

Principle Investigator Kursten Pierce Description The purpose of this study is to evaluate whether three times weekly dosing with oral rapamycin can reverse the heart muscle changes associated with subvalvular aortic stenosis (SAS) in dogs. Dogs will undergo an initial screening for eligibility. If your dog enrolls, they will be randomized to receive either low… 

May 13, 2024

Canine Clinic Connections: Investigating Dog-Human Dynamics in Veterinary Settings

Description There are many potential factors that may influence a dog’s experience at the veterinary clinic. NC State University College of Veterinary Medicine Thinking Pets Program is now enrolling dogs and their owners for a new research study exploring dog and human factors that may influence dog behavior in the veterinary clinic. We hope to use… 

Apr 12, 2024

Now Recruiting Dogs with Babesia gibsoni

Principle Investigator Dr. Birkenheuer Description NC State College of Veterinary Medicine is enrolling dogs with Babesia gibsoni in a trial to evaluate if the use of a new drug combination (atovaquone/proguanil hydrochloride, azithromycin, and artemisinin) can improve treatment outcomes. A new treatment regimen using atovaquone/proguanil hydrochloride, azithromycin, and an artemisinin derivative has recently been shown to… 

Mar 14, 2024

Dog Owners – The Thinking Pets Research Program Wants to Hear From You!

The Thinking Pets Research Program is interested in learning more about potential dog and human factors that may influence your dog’s experience at the veterinary clinic. Help our researchers from the comfort of your home! No need to come into the veterinary school this time. All dog owners who are 18+ and have owned their… 

Jan 26, 2024

Now Enrolling Dogs with Early Stage Oral Malignant Melanoma

Principle Investigator Dr. Michael Nolan Description NC State University Veterinary Hospital is looking for dogs with stage I or II with oral melanoma for a clinical trial using a new therapeutic drug (GM-1111) and standard-of-care radiotherapy. The purpose of this clinical trial is to evaluate whether the novel therapy has: 1. Direct anti-cancer activity, 2. Capacity… 

Nov 9, 2023

Riluzole as a Neuroprotectant in Canine Degenerative Myelopathy

Principle Investigator Dr Natasha Olby Description This study will evaluate the effect of Riluzole, a drug already FDA-approved for the treatment of human ALS, on the progression of clinical signs in dogs with degenerative myelopathy (DM). This therapy has been previously tested for safety in dogs. The study will be randomized and blinded. This means… 

Oct 20, 2023

Now Enrolling Dogs with Invasive Bladder Cancer

Principle Investigator Dr. Paul Hess Description NC State Medical Oncology is enrolling patients for a clinical trial of an experimental immunotherapy for the treatment of bladder cancer. The primary purpose of this study is to investigate the safety and immune-stimulating properties of a novel therapy being developed at NCSU. Testing Requirements 8-day study (Monday – Monday)… 

Oct 16, 2023

Research Study for Senior Dogs: Targeting Frailty To Improve Healthspan and Well-Being

Description Over the past decade, there has been an increased interest in assessing frailty in our aging companion animals. The goal of this study is to monitor how frailty in senior dogs progresses over time, and how activity impacts their well-being. We hope to use what we learn to better care for our aging four… 

Oct 3, 2023

Seasonal Effect on Allergy Testing in Dogs with Atopic Dermatitis

Principle Investigator Dr. Petra Bizikova Description NC State Dermatology is looking for dogs that have Atopic Dermatitis due to airborne allergens to investigate the changes in the pattern and rate of allergen positivity during the different pollen peak seasons. The goal is to obtain a more comprehensive and accurate picture of the allergens that should be… 

Oct 3, 2023

Assessment of Hindlimb Function & Perfusion after Transcatheter PDA Occlusion

Principle Investigator Dr. Kursten Pierce Description Each patient undergoing transcatheter PDA occlusion will be assigned to either the femoral artery ligation group or the femoral artery repair group. Both methods have been described in literature and applied in practice as standard of care. Femoral artery repair will be performed by an experienced cardiology interventionalist to…