Cardiology

Mar 18, 2025

Cats with Hypertrophic Cardiomyopathy: The HALT HCM Study

Principle Investigator Sandra Tou Description This is a blinded, randomized, placebo-controlled clinical field study to provide substantial evidence of effectiveness of a disease modifying drug intervention in the management of ventricular hypertrophy in cats with subclinical Hypertrophic Cardiomyopathy (HCM). The study will consist of up to a 14-day screening period, followed by a 12-month once-weekly…

Jun 3, 2024

Feline Congestive Heart Failure and Coagulation

Principle Investigator Teresa DeFrancesco Description Cats with congestive heart failure (abnormal fluid accumulation) are at high risk for developing blood clots but the risk appears to differ with the manifestation of heart failure. There are two different manifestations of congestive heart failure in cats: 1) primarily pulmonary edema, and 2) primarily pleural effusion. Pulmonary edema…

May 29, 2024

Oral rapamycin for Severe Subvalvular Aortic Stenosis (SAS) in Dogs

Principle Investigator Kursten Pierce Description The purpose of this study is to evaluate whether three times weekly dosing with oral rapamycin can reverse the heart muscle changes associated with subvalvular aortic stenosis (SAS) in dogs. Dogs will undergo an initial screening for eligibility. If your dog enrolls, they will be randomized to receive either low…

Oct 3, 2023

Assessment of Hindlimb Function & Perfusion after Transcatheter PDA Occlusion

Principle Investigator Dr. Kursten Pierce Description Each patient undergoing transcatheter PDA occlusion will be assigned to either the femoral artery ligation group or the femoral artery repair group. Both methods have been described in literature and applied in practice as standard of care. Femoral artery repair will be performed by an experienced cardiology interventionalist to…

Aug 3, 2022

EARLY INTERVENTION FOR DOBERMAN PINSCHERS AT RISK OF DEVELOPING DILATED CARDIOMYOPATHY

Principal Investigator Kathryn Meurs Description We recently identified a genetic mutation in the Titin gene as a common cause of fatal dilated cardiomyopathy in the Doberman pinscher. Dogs that develop the disease frequently die of the disease either from refractory congestive heart failure or sudden cardiac death. Previous studies have demonstrated that medical intervention of…