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Assessment of Hindlimb Function & Perfusion after Transcatheter PDA Occlusion

Principle Investigator

Dr. Kursten Pierce


Each patient undergoing transcatheter PDA occlusion will be assigned to either the femoral artery ligation group or the femoral artery repair group.

Both methods have been described in literature and applied in practice as standard of care. Femoral artery repair will be performed by an experienced cardiology interventionalist to limit the risk of complications.

The Cardiology Service is looking to obtain and compare data to assess if hindlimb function and perfusion are affected by femoral artery ligation as compared to femoral artery repair.

Testing Requirements

A 2-3 overnight stay for the pre-op workup and procedure and 2 additional free recheck appointments with the NCSU cardiology service at 10-14 days post-procedure and at 3 months.

Enrollment Start


Enrollment Finish



Patients must have a left-to-right shunting Patent Ductus Arteriosus (PDA).
This will be confirmed via echocardiogram on evaluation of NCSU.
Potential eligible candidates to consider are dogs with a continuous heart murmur.
Patients must weigh at least 5 kg at the time of PDA occlusion procedure.


o Financial benefit of ~$1,800 to $2,000!
o Chemistry blood panel at each appointment
o Free echocardiogram (heart ultrasound)
o Free ACDO device for procedure
o Free 10-14 days and 3-month recheck appointments
o Neurology/orthopedic evaluations
o The feeling of accomplishment for contributing to science!




For additional information please contact the NCSU Cardiology Service.
Phone: 919-513-6694