Skip to main content
Research Study for Senior Dogs: Targeting Frailty To Improve Healthspan and Well-Being

Dogs

Mar 4, 2026

Medically managing non-ambulatory dogs with disc herniation

Principle Investigator Natasha Olby and Melissa Lewis Description Our overall objective is to comprehensively document the recovery trajectory in medically managed, non-ambulatory dogs with presumptive or confirmed thoracolumbar intervertebral disc extrusion (TL-IVDE) presented to primary care (general practice or emergency) veterinarians. We seek to identify the most appropriate dogs for medical management and to optimize…

Mar 2, 2026

Now Recruiting Dogs with Keratoconjunctivitis Sicca (KCS)

Principle Investigator Vanessa Raphtis and Michala de Linde Description This clinical trial is investigating a novel sustained-release treatment for canine KCS (“drye eye disease”) using a single subconjunctival injection of cooked platelet-rich fibrin combined with tacrolimus (cPRFT) Testing Requirements Each dog enrolled will: -Receive standard topical tacrolimus therapy in the right eye (OD) -Receive a…
dog looking at camera, text says what shapes how dogs think and feel?

Jan 5, 2026

Assessing emotional and cognitive domains in dogs

Principle Investigator Margaret Gruen Description The purpose of this study is to develop a battery of cognitive and emotional tasks to assess the emotional and cognitive domains in dogs with and without chronic osteoarthritis (OA) pain. This will be the first study of its kind to fully develop and validate a cognitive and emotional assessment…

Dec 19, 2025

Recruiting Healthy Soft Coated Wheaten Terriers

Principle Investigator Dr Grady Description We are recruiting for a study to evaluate how diet will benefit soft coated wheaten terriers (SCWT), which are a breed known to be predisposed to chronic gastrointestinal (GI) disease. SCWTs are prone to developing severe GI signs. We have determined that SCWT develop changes in their gut before clinical…

Sep 23, 2025

Become a Canine Cancer Hero

Principle Investigator Dr. Yea Ji Jeong Description What is the Legacy Tissue Donation Program?• Patients’ family agree to donate tumor/metastases tissue after death • High quality biospecimens are obtained for cancer research (1-2 hours after death)• A board-certified veterinary anatomic pathologist supervises collection of only the necessary tumor and metastatic tissue.• Samples are analyzed for…
dogs running in field

Aug 29, 2025

GOS Supplement Clinical Study

Fill Out Our 3-5 Minute Questionnaire!? Enrollment Benefits Description Helping advance canine joint health We’re enrolling dogs with osteoarthritis or mobility problems to study the connection between gut health and osteoarthritis. Visits are designed to be low-stress and Fear Free, include imaging and specialized walking and standing data, as well as multiple opportunities to learn…

Aug 22, 2025

Now Recruiting Dogs with Soft Tissue Sarcoma

Principle Investigator Dr Nolan Description This trial investigates a strategy to improve cancer control using a combination of standard radiation therapy plus a new immunotherapy drug called XCSgel. All enrolled dogs will receive surgery to remove the tumor. Because this is a blinded study, you will not know if your dog was given XCSgel or…

Mar 13, 2025

Now Recruiting Dogs with Acute Blindness Suspected to be Due to Optic Neuritis

Principle Investigator Dr Annie Oh Description Ophthalmology at NC State College of Veterinary Medicine is enrolling in a clinical study to measure VEPs (visual evoked potentials) and RNFL (retinal nerve fiber layer) thickness in dogs within 2 weeks of the onset of acute optic neuritis. The goal is to assess whether the presence or absence…

Mar 6, 2025

Now Recruiting Dogs with Bone Cancer

Principle Investigator Dr. Nolan Description NC State is recruiting dogs with bone cancer (osteosarcoma) for a clinical trial that compares 2 radiotherapy approaches. Each enrolled dog will get a singledose of radiotherapy, followed within 3 weeks by standard surgery (limb amputation). Testing Requirements Large or giant breed dogs may be eligible if they have:– X-rays…

Jan 6, 2025

Research Study for Senior Dogs: Targeting Frailty To Improve Healthspan and Well-Being

Description Over the past decade, there has been an increased interest in assessing frailty in our aging companion animals. The goal of this study is to monitor how frailty in senior dogs progresses over time, and how activity impacts their well-being. We hope to use what we learn to better care for our aging four…