Now Enrolling Canine Patients with Liver Tumors

Principle Investigator

Dr. Mike Sano

Description

Does your dog have a liver tumor? We are now enrolling canine patients that have a liver tumor into a clinical trial that is using a new therapy called INSPIRE, which uses electrical pulses to safely destroy the cells within a tumor.

This study has two treatment groups.

One group of study applicants that have 1-2 liver tumor measuring between 1-3cm will be screened through the Medical Oncology service at NC State Veterinary hospital for eligibility. If eligible, patients in this group will return one week later for a one time INSPIRE therapy treatment. This will be followed by a surgery a week later to remove the tumor and part of the liver.

The second group of study applicants should have 1-2 liver tumor measuring between 1-3cm. Potential candidates will come in through the Medical Oncology service at NC State Veterinary Hospital for a screening appointment to check eligibility for enrollment. If eligible, patients will return one week later for a one time INSPIRE therapy treatment. Patients will then be monitored over a 9 month period which include five recheck appointments. During which patients will receive a CT scan and bloodwork to monitor the destruction of the tumor.

Testing Requirements

Patients should have a cytological diagnosis of the liver tumor prior to their screening appointment.

Enrollment Start

07/01/2023

Enrollment Finish

07/01/2026

Inclusion Criteria

Patients that have 1-2 liver tumors measuring between 1-3cm

Patients must weigh at least 30lbs

Patients must be overall healthy with no other major health concerns

Exclusion Criteria

Patients with cavitated liver tumors

Metastasis of the liver tumor or any other forms of cancer

Major heart disease or heart arrhythmia’s

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Contact

Please contact Jewels Darrow at 919-515-5090 or email jldarro2@ncsu.edu for more information.