Dogs

Oct 20, 2023

Now Enrolling Dogs with Invasive Bladder Cancer

Principle Investigator Dr. Paul Hess Description NC State Medical Oncology is enrolling patients for a clinical trial of an experimental immunotherapy for the treatment of bladder cancer. The primary purpose of this study is to investigate the safety and immune-stimulating properties of a novel therapy being developed at NCSU. Testing Requirements 8-day study (Monday –…

Oct 16, 2023

Research Study for Senior Dogs: Targeting Frailty To Improve Healthspan and Well-Being

Description Over the past decade, there has been an increased interest in assessing frailty in our aging companion animals. The goal of this study is to monitor how frailty in senior dogs progresses over time, and how activity impacts their well-being. We hope to use what we learn to better care for our aging four…

Oct 3, 2023

Assessment of Hindlimb Function & Perfusion after Transcatheter PDA Occlusion

Principle Investigator Dr. Kursten Pierce Description Each patient undergoing transcatheter PDA occlusion will be assigned to either the femoral artery ligation group or the femoral artery repair group. Both methods have been described in literature and applied in practice as standard of care. Femoral artery repair will be performed by an experienced cardiology interventionalist to…

Sep 28, 2023

Enrolling Dogs With Stifle or Hip Osteoarthritis on a Study Involving LIBRELA

Principle Investigator Masataka Enomoto, B. Duncan X. Lascelles Description Translational Research in Pain team is seeking dogs with osteoarthritis to take part in astudy aiming to compare the efficacy of two FDA-approved medications. We will do thisusing computerized analysis of gait. Enrolled dogs will all receive one of the FDAapproved drugs. (Half of the dogs…

Aug 3, 2023

Immunotherapy Clinical Trial for Patients with Oral Melanoma

Principal Investigator Dr. Michael Nolan Description NC State Veterinary Hospital is now recruiting dogs with oral malignant melanoma to evaluate the safety, tolerability, and efficacy of a novel immunotherapy. The immunotherapy is an antibody that aims to invigorate your dog’s immune system and help it eliminate cancer cells. Study Requirements Follow-up: After your screening appointment,…

Jul 18, 2023

Now Enrolling Canine Patients with Liver Tumors

Principle Investigator Dr. Mike Sano Description Does your dog have a liver tumor? We are now enrolling canine patients that have a liver tumor into a clinical trial that is using a new therapy called INSPIRE, which uses electrical pulses to safely destroy the cells within a tumor. This study has two treatment groups. One…

Feb 2, 2023

THE IMPACT OF GI HEALTH ON JOINTS: A CLINICAL STUDY

Principal Investigator Duncan Lascelles Description NC State University College of Veterinary Medicine is seeking dogs with or without mobility problems that are 5 years of age or older and weigh at least 10 kg to take part in a study aiming to evaluate the relationship between intestinal permeability and multiple joint osteoarthritis. Eligibility To be…

Jan 31, 2023

Screening urine samples from high-risk dog breeds for early bladder cancer

Principal Investigator Dr Shelly Vaden Description This study is screening urine samples from clinically healthy dogs at increased risk of bladder cancer, to determine if they test positive for a genetic marker of the disease (a specific mutation in the dog BRAF gene). The goal is to determine whether this BRAF Mutation Detection test can…

Jan 31, 2023

Therapeutic trials for canine bladder cancer (NOT CURRENTLY RECRUITING)

Principal Investigator Dr Shelly Vaden Description This study will investigate whether the administration of a dietary supplement slows the progression of canine bladder cancer (also known as transitional cell carcinoma/urothelial carcinoma, or TCC/UC) in dogs treated with standard of care therapy Testing Requirements Participants will be asked to: – bring their dog for an initial…

Jan 19, 2023

Now Enrolling Dogs with Bladder Cancer

Principal Investigator Dr. Michael Mastromauro Description NC State University College of Veterinary Medicine is enrolling in a clinical trial to investigate if a probiotic can improve cancer care and outcomes in dogs with bladder cancer. This is a placebo-controlled study, not all dogs will receive the probiotic, but all dogs will receivechemotherapy (vinblastine/piroxicam). Testing Requirements…