clinical_trial

Nov 9, 2023

Riluzole as a Neuroprotectant in Canine Degenerative Myelopathy

Principle Investigator Dr Natasha Olby Description This study will evaluate the effect of Riluzole, a drug already FDA-approved for the treatment of human ALS, on the progression of clinical signs in dogs with degenerative myelopathy (DM). This therapy has been previously tested for safety in dogs. The study will be randomized and blinded. This means… 

Oct 20, 2023

Now Enrolling Dogs with Invasive Bladder Cancer

Principle Investigator Dr. Paul Hess Description NC State Medical Oncology is enrolling patients for a clinical trial of an experimental immunotherapy for the treatment of bladder cancer. The primary purpose of this study is to investigate the safety and immune-stimulating properties of a novel therapy being developed at NCSU. Testing Requirements 8-day study (Monday – Monday)… 

Oct 16, 2023

Research Study for Senior Dogs: Targeting Frailty To Improve Healthspan and Well-Being

Description Over the past decade, there has been an increased interest in assessing frailty in our aging companion animals. The goal of this study is to monitor how frailty in senior dogs progresses over time, and how activity impacts their well-being. We hope to use what we learn to better care for our aging four… 

Oct 3, 2023

Seasonal Effect on Allergy Testing in Dogs with Atopic Dermatitis

Principle Investigator Dr. Petra Bizikova Description NC State Dermatology is looking for dogs that have Atopic Dermatitis due to airborne allergens to investigate the changes in the pattern and rate of allergen positivity during the different pollen peak seasons. The goal is to obtain a more comprehensive and accurate picture of the allergens that should be… 

Oct 3, 2023

Assessment of Hindlimb Function & Perfusion after Transcatheter PDA Occlusion

Principle Investigator Dr. Kursten Pierce Description Each patient undergoing transcatheter PDA occlusion will be assigned to either the femoral artery ligation group or the femoral artery repair group. Both methods have been described in literature and applied in practice as standard of care. Femoral artery repair will be performed by an experienced cardiology interventionalist to… 

Sep 28, 2023

Enrolling Dogs With Stifle or Hip Osteoarthritis on a Study Involving LIBRELA

Principle Investigator Masataka Enomoto, B. Duncan X. Lascelles Description Translational Research in Pain team is seeking dogs with osteoarthritis to take part in a study aiming to compare the efficacy of two FDA-approved medications. We will do this using computerized analysis of gait. Enrolled dogs will all receive one of the FDA approved drugs. (Half… 

Aug 3, 2023

Immunotherapy Clinical Trial for Patients with Oral Melanoma

Principal Investigator Dr. Michael Nolan Description NC State Veterinary Hospital is now recruiting dogs with oral malignant melanoma to evaluate the safety, tolerability, and efficacy of a novel immunotherapy. The immunotherapy is an antibody that aims to invigorate your dog’s immune system and help it eliminate cancer cells. Study Requirements Follow-up: After your screening appointment, you… 

Jul 18, 2023

Now Enrolling Canine Patients with Liver Tumors

Principle Investigator Dr. Kyle Mathews Description Does your dog have a liver tumor? We are now enrolling canine patients that have a liver tumor into a clinical trial that is using a new therapy called INSPIRE, which uses electrical pulses to safely destroy the cells within a tumor. This study has two treatment groups. One… 

May 12, 2023

Osteoarthritis Oral Microbiome Analysis in Cats

Principal Investigator Jody Gookin Description A one-time saliva sample from your cat to analyze their oral microbiome (the microbial composition of their mouths.) The analysis will allow us to identify patterns associated with the presence or absence of certain diseases. Testing Requirements A one-time visit to NCSU for a physical examination and saliva sample. There… 

Feb 2, 2023

THE IMPACT OF GI HEALTH ON JOINTS: A CLINICAL STUDY

Principal Investigator Duncan Lascelles Description We are excited to update you on the progress of our clinical study. Due to overwhelming interest and participation, we have temporarily paused enrollment to ensure the highest quality of care and attention to each participant. We anticipate resuming enrollment in late July and encourage you to stay tuned for…