INSPIRE THERAPY FOR CANINE MAMMARY CARCINOMA

Principal Investigator

Dr. Mike Sano

Description

This study is looking for dogs with 1-2 discrete mammary tumors measuring between 1-3cm to participate in a clinical trial that is investigating a new therapy called INSPIRE, which uses electrical pulses to safely destroy the membranes of cells within a tumor.

Owners will need to bring their dog to the NC State Veterinary Hospital for a screening appointment. to see if the patient is eligible to participate in the clinical trail. The screening includes a cardiology and oncology consult, thoracic radiographs, abdominal ultrasound, bloodwork, and initial CT scan

If the patient is eligible for enrollment after the screening appointment, they will return a week later for a single INSPIRE therapy treatment. Followed by five recheck appointments over 9 months that include bloodwork and a CT scan.

Testing Requirements

Patients who are suspected of having mammary carcinoma.

Enrollment Start

7/01/2023

Enrollment Finish

7/01/2026

Eligibility

• Patients that have 1-2 discrete tumors measuring between 1-3cm
• Patients must weigh at least 30lbs
• Patients that have been previously spayed

Exclusions

• Patients that have tumors greater than 4cm
• Patients that are in poor health
• Patients that are not eligible for general anesthesia
• Tumors that have metastasized

Flyer

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Contact

Please contact Jewels Darrow at 919-515-5090 or email jldarro2@ncsu.edu