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Mark Papich


CVM Main Building C282


Dr. Mark G. Papich is a Professor of Clinical Pharmacology and the Burroughs Wellcome Fund Professorship in Veterinary Pharmacology at North Carolina State University. He is the Supervisor of the Clinical Pharmacology Laboratory in the College of Veterinary Medicine at North Carolina State University. He is a diplomate in the American College of Veterinary Clinical Pharmacology (ACVCP), and has served as president of ACVCP. He has served on various Expert Committees: the Council of Experts, and Chairman for the Veterinary Drugs Expert Committee for the United States Pharmacopeia (USP), and is a current member of the USP Expert Committee on Antibiotics. He is a member of the AVMA Committee on Antibiotics (CoA). He is a member and past Chairholder of the Clinical Laboratory Standards Institute (CLSI) Veterinary Antimicrobial Susceptibility Testing subcommittee (VAST) and chair of CLSI working groups. He served as a member of the Veterinary Medicine Advisory Committee of the Food and Drug Administration (FDA). He has taught veterinary pharmacology for over 30 years.

He has authored/edited eight books on veterinary pharmacology and is one of the editors of the 9th and 10th editions of Veterinary Pharmacology and Therapeutics. He is author or co-author of over 275 research papers published in refereed journals and has authored over 135 book chapters, and review papers (h-index 56). He has several awards including the Zoetis Distinguished Veterinary Teacher Award and the Faculty Award presented to the outstanding teacher by veterinary classes. He was also awarded the Pfizer Award for Research Excellence, the Excellence in Consensus Management by the Clinical and Laboratory Standards Institute (CLSI), the Lloyd E. Davis Award by the AAVPT, the Distinguished Fellow Award from AAVPT, and the Huffman Leadership Award from NC State University. He has also delivered hundreds of presentations on veterinary pharmacology at national and international veterinary meetings, conferences and symposia.

A list of Dr. Papich’s publications can be found below:
Google Citations
NC State Citation Index


American Veterinary Medical Association (AVMA), American Academy of Veterinary Pharmacology and Therapeutics (AAVPT, Distinguished Fellow), American College of Veterinary Clinical Pharmacology (ACVCP), United States Pharmacopeia (USP), and Clinical and Laboratory Standards Institute (CLSI).


American College of Veterinary Clinical Pharmacology (ACVCP)

Area(s) of Expertise

The research program in veterinary clinical pharmacology at North Carolina State University College of Veterinary Medicine consists of studies designed to define and improve rational drug therapy in animals. The research emphasis includes studies in a wide variety of animal species, including dogs, cats, horses, ruminants, zoo animals, reptiles, fish, and birds. Current studies focus on the disposition of antibiotics, antifungal drugs, anti-inflammatory drugs, gastrointestinal drugs, and analgesic drugs in a variety of animal species. We also have studies on-going to investigate treatment of opioid overdose using animal models. Studies originate from our laboratory, or are performed in collaboration with clinical faculty at NCSU, and investigators at other veterinary colleges, zoos, or pharmaceutical companies. The Clinical Pharmacology Laboratory is equipped with state-of-the-art analytical equipment and has procedures for analyzing most medications administered to animals. The Laboratory maintains software licenses for current pharmacokinetic software capable of performing traditional compartmental modeling, non-compartmental pharmacokinetics, pharmacokinetic-pharmacodynamic (PK-PD) analysis, and nonlinear mixed-effects modeling (NLME) for population studies.


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