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Nick Buchler

Assoc Professor


CVM Research Building 390


Dr. Nicolas Buchler joined NC State in July 2018 as a Chancellor’s Faculty Excellence Program cluster hire in Modeling the Living Embryo. His research is focused on understanding how the cell cycle interacts with metabolic rhythms, and how changes in these interactions lead to disease or new functions. The lab primarily works with early-diverging Fungi and yeasts, but they collaborate with others to study these same questions in other regulatory systems (e.g. circadian clocks) and organisms (e.g. animals and plants).

Dr. Buchler received a B.S. in Physics from the University of California at San Diego, before working on protein structure and evolution while obtaining a Ph.D. in Biophysics at the University of Michigan at Ann Arbor. During his post-doc, first at the University of California at San Diego and then at the Center for Studies in Physics & Biology at Rockefeller University, he combined mathematical modeling and experiments to understand how networks of genes sense and respond to multiple signals, store memories of past events, and schedule periodic events (e.g. cell cycle).


PhD Biophysics University of Michigan 2001

Area(s) of Expertise

I am a biophysicist and geneticist by training with expertise in biological oscillations (e.g., cell cycle, metabolic rhythms), fungal genomics and evolution, single-cell gene expression, and mathematical modeling of gene regulatory dynamics.


View all publications 
  • NIH Director's New Innovator Award, National Institutes of Health, 2011
  • Career Award at the Scientific Interface, Burroughs Wellcome Funds, 2006