Yogesh Saini

Bio

Lab Website

Dr. Saini received his DVM (1996-2001) from College of Veterinary Sciences, Palampur (India) and MVSc in Veterinary Biochemistry and Biotechnology (2001-2003) from College of Veterinary Sciences, Pantnager (India). Thereafter, he completed a Senior Research Fellowship (2003-2005) at Indian Veterinary Research Institute, Izatnagar (India). He received a dual-PhD (Genetics and Toxicology) under the supervision of Dr. John LaPres at Michigan State University in 2009. After completing postdoctoral training (2010-2014) in the laboratory of Dr. Richard Boucher at the University of North Carolina (UNC), he was promoted to the rank of research instructor at Marsico Lung Institute. He then joined LSU/SVM in 2014 as a tenure-track Assistant Professor. In 2019, he received early tenure with promotion to Associate Professor. Most recently in August 2023, he joined NCSU/CVM as full professor in the department of Population Health and Pathobiology.

Area(s) of Expertise

Lung Inflammation, Macrophage Biology, Inhalation Toxicology, Hepatotoxicity

Publications

• Airway epithelial cell-specific deletion of EGFR modulates mucoinflammatory features of cystic fibrosis-like lung disease in mice , FRONTIERS IN IMMUNOLOGY (2025)
• Optimizing Neutrophil Recruitment to Tackle Bacterial Infections? , American journal of respiratory cell and molecular biology (2025)
• Repetitive ozone exposure worsens features of muco-inflammatory disease in developed Scnn1b-Tg+ mice lungs , FRONTIERS IN TOXICOLOGY (2025)
• Airspaces-derived exosomes contain disease-relevant protein signatures in a mouse model of cystic fibrosis (CF)-like mucoinflammatory lung disease , FRONTIERS IN PHARMACOLOGY (2024)
• Cell-Specific Contribution of IL-4 Receptor α Signaling Shapes the Overall Manifestation of Allergic Airway Disease , AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2024)
• Comparative transcriptomic analyses of in vivo-differentiated alveolar macrophages reveals unique as well as differential gene signatures and , JOURNAL OF IMMUNOLOGY (2024)
• Myeloid cell-specific HMGB1 deficiency exaggerates mucoinflammatory response in Scnn1b-Tg+ mice , (2024)
• Net-Shaped DNA Nanostructures Designed for Rapid/Sensitive Detection and Potential Inhibition of the SARS-CoV-2 Virus , Journal of the American Chemical Society (2024)
• Protocol for X-ray irradiation of C57BL/6J recipient mice followed by the transplantation of mTomato-expressing bone marrow cells , STAR PROTOCOLS (2024)
• Role of Myeloid Cell-Specific Adenylyl Cyclase Type 7 in Lipopolysaccharide- and Alcohol-Induced Immune Responses , International Journal of Molecular Sciences (2024)

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