Now Recruiting Dogs with Keratoconjunctivitis Sicca (KCS)

Principle Investigator Vanessa Raphtis and Michala de Linde Description This clinical trial is investigating a novel sustained-release treatment for canine KCS (“drye eye disease”) using a single subconjunctival injection of cooked platelet-rich fibrin combined with tacrolimus (cPRFT) Testing Requirements Each dog enrolled will: -Receive standard topical tacrolimus therapy in the right eye (OD) -Receive a…

TRAP-Paclitaxel for Equine Eyelid Squamous Cell Carcinoma

Principle Investigator Dr. Annie Oh Description This is a dose-escalation clinical trial to determine the effectiveness of a novel chemotherapeutic drug, TRAP-Paclitaxel, for the treatment of equine squamous cell carcinoma (SCC). The study will consist of an initial visit with biopsy, and 1-3 injections of TRAP-Paclitaxel at a minimum of 6 weeks apart. Horses will…

Now Recruiting Dogs with Acute Blindness Suspected to be Due to Optic Neuritis

Principle Investigator Dr Annie Oh Description Ophthalmology at NC State College of Veterinary Medicine is enrolling in a clinical study to measure VEPs (visual evoked potentials) and RNFL (retinal nerve fiber layer) thickness in dogs within 2 weeks of the onset of acute optic neuritis. The goal is to assess whether the presence or absence…

CLINICAL TRIAL FOR DOGS WITH PRIMARY ANGLE CLOSURE GLAUCOMA

Principal Investigator Hans Westermeyer Testing Requirements Your dog will receive an exam from the NC State Ophthalmology Service 1 month after study enrollment and once every 3 months thereafter. Each visit will include: sedation, a complete ophthalmic exam, photography and ultrasound of the eye’s drainage apparatus, retinal thickness measurement, and quantitative pupillary light reflex evaluation.…