Overview
The Cell Biology Concentration Area encompasses research at the molecular and cellular levels in the following disciplines: gastroenterology, oncology, pulmonary biology, ophthalmology, reproductive endocrinology, pharmacology, neurophysiology and neuroanatomy, and cellular differentiation and morphogenesis. Research approaches employ a wide variety of molecular, biochemical, pharmacological, and microscopic techniques, utilizing cell culture and whole organisms. Students selecting Cell Biology will focus their research efforts on one or more of these areas.
A highly individualized curriculum of study is designed to meet the needs and interests of the student while satisfying selected requirements by the faculty. These include graduate level cell biology, biochemistry, and cell biology seminars. Additional courses may be chosen by the student and his/her advisor from a large number of college and university offerings.
COURSES REQUIRED FOR THE CELL BIOLOGY CONCENTRATION
GN701 Molecular Genetics; Fall (3 credits)
CBS 770 Cell Biology; Spring (4 credits)
CBS 809 Seminar in Cell Biology (1 credit; minimum 3 credits total for doctoral students; minimum 2 credits total for master’s students)
ELECTIVE COURSES
Elective courses are selected by the student and mentor, and must be approved by the student’s graduate advisory committee. Possible elective course include, but are not limited to, the following:
BCH 701 Macromolecular Structure; Fall (3 credits)
BCH 703 Macromolecular Synthesis and Regulation; Fall (3 credits)
BCH 705 Molecular Biology of the Cell; Spring (3 credits)
GN 701 Molecular Genetics; Fall (3 credits)
GN 702 Cellular and Developmental Genetics; Spring (3 credits)
GN 750 Developmental Genetics; Spring alternate years(3 credits)
GN/MB 758 Microbial Genetics & Genomics; Spring (3 credits)
GN 761 Advanced Molecular Biology of the Cell; Spring alternate years (3 credits)
GN/BCH 768 Nucleic Acids: Structure and Function; Spring alternate years (3 credits)
CBS/IMM/MB 783 Advanced Immunology; Fall alternate odd years (3 credits)
CBS/IMM 816 Advanced Topics in Immunology; Fall (1 credits)
MB 718 Introductory Virology; Fall alternate odd years (3 credits)
IMM/TOX 705 Immunotoxicology; Spring (2 credits)
IMM 751 Immunology; Spring (3 credits)
PHY 503, 504 General Physiology I and II (3 credits)
PHY 702 Reproductive Physiology of Mammals; Fall & Spring (3 credits)
PHY 780 Mammalian Endocrinology (3 credits)
ST 701 Statistical Theory I; Fall (3 credits)
TOX 501 Principles of Toxicology; Spring (4 credits)
Participating Faculty
| Name | Email | Primary Concentration | Other Concentrations | Research Emphasis |
| Amanda Ziegler | [email protected] | Cell Biology | | Development of epithelial barrier repair signaling in the neonatal gut |
| Anthony Blikslager | [email protected] | Cell Biology | | Mechanisms of intestinal mucosal injury and repair |
| Ashley Brown | [email protected] | Cell Biology | Immunology | Dr. Brown leads the Advanced Wound Healing lab. |
| Breanna Sheahan | [email protected] | Cell Biology | | The Sheahan Lab is focused on equine gastrointestinal diseases and finding new therapies to treat or prevent these diseases.
|
| Brian Gilger | [email protected] | Pharmacology | Cell Biology | Ocular inflammation, drug delivery, gene therapy, fungal keratitis, and imaging of the eye |
| Caroline Laplante | [email protected] | Cell Biology | | Understanding how a mother cell divides into two daughter cells. |
| Carolyn Mattingly | [email protected][email protected] | Cell Biology | Pharmacology, Population Medicine and Global Health | My overarching professional goal is to improve understanding about environmental influences on human health and disease. Currently, I am doing this by:
Overseeing the ongoing development and expansion of the Comparative Toxicogenomics Database (CTD),
Providing administrative oversight of NC State’s Superfund Center for Environmental and Health Effects of PFAS. |
Caroline McKinney-Aguirre
| [email protected] | Cell Biology | | The role of intestinal stem cells and their interaction with elements of the intestinal microenvironment, like bacteria. |
| Christophe Guilluy | [email protected] | Cell Biology | | Investigating how mechanical constraints control cellular behavior in physiology and disease. |
| Duncan Lascelles | [email protected] | Cell Biology | Neurosciences | Measurement and neurobiology of pain in induced and naturally occurring animal models |
| Erik (Yen-Hao) Lai | [email protected]
| Cell Biology | Radiation Oncology | |
| Glenn Cruse | [email protected] | Immunology | Cell Biology, Pharmacology | Translational research in mast cell-driven diseases such as allergy, asthma and mastocytosis. |
Ian Williamson
| [email protected] | Cell Biology | Neurosciences, Pharmacology | Enterocyte metabolism and nutrient uptake
|
| James Bonner | [email protected] | Cell Biology | Toxicology | Our goal is to explore and investigate mechanisms of environmental lung diseases (asthma, fibrosis, cancer) caused by emerging toxicants that pose a threat to human health and the environment.
|
| Javier Lopez Soto | [email protected] | Neurosciences | Cell Biology | Neurosciences and Cell Biology |
| Jeffrey Eells | [email protected] | Cell Biology | | The overarching theme of my research is understanding how the environment can alter brain function. |
| Jeff Yoder | [email protected] | Immunology | Infectious Disease, Cell Biology | We study the evolution of immune receptors and PFAS immunotoxicology. |
| Jennifer Halleran | [email protected] | Pharmacology | Cell Biology, Infectious Diseases | Antimicrobial Resistance |
| Jody Gookin | [email protected] | Cell Biology | Infectious Diseases | Host-pathogen Interactions in the Gut |
| Jonathan Hall | [email protected] | Cell Biology | | Research in the Hall Lab is focused on the identification and characterization of genes and signaling pathways that determine susceptibility to skin cancer. |
| Jorge Piedrahita | [email protected] | Cell Biology | | Use of stem cells in regenerative medicine |
| Joshua Stern | [email protected] | Cell Biology | Pathology | The Stern laboratory studies spontaneous animal models of familial cardiac disease. Our research efforts focus on identification of causative mutations in spontaneous animal models, evaluation of cardiovascular pharmacogenetic effects and the study of novel cardiovascular therapeutics. |
| Kelly Ann Meiklejohn | [email protected] | Cell Biology | | New techniques for analyzing forensic evidence using next generation sequencing. |
| Michala de Linde Henriksen | [email protected]
| Cell Biology | Pharmacology | Dr. Henriksen's research interest is immunotherapy of ocular diseases, such as anterior uveitis, as well as ocular microbiology with a focus on infected corneal ulcerations. |
| Kenneth Adler | [email protected] | Cell Biology | | molecular mechanisms of inflammation and carcinogenesis |
| Lauren Schnabel | [email protected] | Cell Biology | Immunology, Infectious Disease | The Schnabel Laboratory focuses on the use of regenerative and biologic therapies for the treatment of musculoskeletal injuries. |
| Laurianne Van Landeghem | [email protected] | Cell Biology | Neurosciences | My lab explores how cues emanating from the microenvironment regulate intestinal epithelial (stem) cells in health and diseases with a special emphasis on cells belonging to the enteric nervous system. |
| Liara Gonzalez | [email protected] | Cell Biology | | Utilizing large animal models to study intestinal stem cell dynamics during clinically relevant disease states. |
| Matthew Breen | [email protected] | Cell Biology | Pathology | Genetics, genomics, comparative aspects of animal and human health. |
| Michael Nolan | [email protected] | Cell Biology | Neurosciences | We study the intersection of cancer and pain. |
| Michele Battle | [email protected] | Cell Biology | | Cellular and Molecular Gastroenterology and Hepatology |
| Mike Sano | [email protected]
| Cell Biology | | Dr. Sano‘s lab studies the complex interaction between cells/tissues and electric fields. |
| Nanette Nascone-Yoder | [email protected] | Cell Biology | | organ development |
| Natasha Olby | [email protected] | Neurosciences | Cell Biology, Pathology | My laboratory focuses on neurological disease in companion dogs with areas of research encompassing aging of the nervous system and neurodegenerative disease, neuropathic pain, and spinal cord injury. |
| Neil McCarthy | [email protected] | Cell Biology | Pathology | Dr. McCarthy's lab investigates intestinal mesenchymal function in development, health, and disease. |
| Nicolas Buchler | [email protected] | Cell Biology | | Fungi, cell cycle, evolution, quantitative biology. |
| Paul Mozdziak | [email protected] | Cell Biology | | Muscle Biology and Cellular Agriculture. |
| Ronald Li | [email protected] | Cell Biology | Immunology | Dr. Li's research focus is directed towards understanding the cellular basis and pathobiological roles of immunothrombosis, by which neutrophils and platelets interact in cardiovascular diseases and systemic inflammation. His research also includes investigating precision medicine, congenital platelet disorders and novel antiplatelet therapy in cardiovascular diseases. |
| Rosemary Bayless | [email protected] | Cell Biology | Immunology, Pharmacology | The Bayless Lab team studies neutrophil biology with the goal of identifying innovative therapeutic targets and developing novel treatments for neutrophil-mediated conditions across veterinary and human patients. |
| Samuel Jones | [email protected] | Cell Biology | Immunology | Regulation of Neutrophil Motility |
| Sarah Shelton | [email protected] | Cell Biology | | Dr. Shelton’s lab designs microfluidic, organ-on-chip models of disease to uncover how the tissue microenvironment and cellular interactions shape pathology and treatment response.
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| Seth Kullman | [email protected] | Cell Biology | | Developmental Endocrinology |
| Shobhan Gaddameedhi | [email protected] | Cell Biology | | Overall, research from the Gaddameedhi lab provides a mechanistic understanding of the biological clock’s role in ‘gene-environment’ interactions and its impact on environmental disease prevention, toxicant exposures, and therapeutic efficacy. |
| Yea Ji Jeong | [email protected] | Cell Biology | Pathology, Population Medicine | Dr. Jeong’s research focuses on creating a precision oncology platform for animal patients. |
| Yogesh Saini | [email protected] | Immunology | Cell Biology, Infectious Disease, Pathology, Pharmacology | Effect of environmental toxins on the lungs and liver |