Matthew Breen, PhD, C. Biol, FRSB
Oscar J. Fletcher Distinguished Professor, Comparative Oncology Genetics
CertificationsFellow, Royal Society of Biology
Computational Biology and Bioinformatics, GeneticsDr. Matthew Breen’s research focuses on genomics, genome mapping and the comparative aspects of canine cancer. In addition his lab is using high throughput molecular cytogenetics for anchoring emerging genome assemblies and for evaluating the changes to genome structure that occur during speciation. The lab is also developing new molecular assays for diagnostic and prognostic use in veterinary medicine.
CVM Study to Use Innovative Cancer Detection Tool, Seeks ParticipantsThe study explores the effectiveness of a new test developed at the CVM for early diagnosis of urothelial carcinoma, a cancer of the urinary tract also known as transitional cell carcinoma.
New Study Aims to Combat Blindness in the Endangered Red WolfA new research project at the NC State College of Veterinary Medicine could make a vital impact on the survival of the critically endangered American red wolf. Only about 40 of the wolves live in the wild, all in North Carolina. Principal investigator Freya Mowat, CVM assistant professor of ophthalmology, has received a grant to
AKC-CHF Grant funds New CVM Bartonella Research ProjectThe new study will dive deeper into evidence suggesting that Bartonella infections contribute to hemangiosarcoma development. That information could lead to improved diagnosis and treatment of the cancer, which occurs most often in several popular canine breeds...
Two NC State Researchers Awarded National Grants to Study Canine HealthTwo of nine grants from the Morris Animal Foundation funding research to improve canine health have been awarded to faculty members from...
Two CVM Researchers Among Recipients of First C3O Cancer GrantsA joint funding project from CVM and the Duke Cancer Institute, the C3O grants support research that will translate laboratory discoveries into therapeutic applications...
News and Updates, April 2016Highlights cover key events; faculty, staff, and student accomplishments; and other CVM news...
Advances in Comparative OncologyThe journal Nature Medicine published a feature article on the comparative oncologist’s current activities on Dec. 8—exactly 10 years to the day from when the journal Nature published the paper documenting the detailed analysis of...
A Researcher's Best Friend: Dogs May Unlock Cancer's Secrets“Usually in the first few minutes of one of my talks somebody will raise their hand and say, ‘I’m sorry, but you’re saying that dogs get cancer?’, “says Dr. Breen...
Breen Named as Fletcher Distinguished ProfessorMatthew Breen, a professor of genomics in the Department of Molecular Biomedical Sciences, has been named the Oscar J. Fletcher Distinguished Professor in Comparative Oncology Genetics. A member of a team that decoded the canine genome in 2005, Dr. Breen is recognized internationally for his research into molecular cytogenetics—the study of the structure and function of cells and chromosomes—and the
CVM Researchers Receive AKC Canine Health Foundation Grants
Researchers at the NC State University College of Veterinary Medicine have been awarded four grants totaling $347,893 from the AKC Canine Health Foundation (CHF) as part of the organization’s 2012 funding year. The AKC CHF-funded NC State CVM research projects are: Grant 1557: High-Resolution Cytogenetic Analysis of Histiocytic Malignancies and Development of a Targeted Assay
Morris Animal Foundation Supports CVM Research
Selected researchers at the North Carolina State University’s College Veterinary Medicine (CVM) are recipients of Morris Animal Foundation grants that total more than $1.2 million for investigations aimed at improving the health of dogs, cats, horses, and wildlife. More specifically, Morris Animal Foundation (MAF) is providing $1,212,671 to help support 12 different studies being conducted
CCMTR-led Research Team Seeking Brain Tumor Gene
Pinpointing the genes involved in human brain cancer can be like looking for a needle in a haystack, and sometimes the needle you find may not be the right one. By comparing human and canine genomes, researchers at North Carolina State University have discovered that a gene commonly believed to be involved in meningiomas—tumors that
Dr. Breen Featured in AKC Canine Health Foundation Podcasts
The American Kennel Club and the AKC Canine Health Foundation produce a podcast series called Genome Barks that feature leading scientists and researchers who have spoken at AKC-CHF Breeder Symposia or who are CHF grant recipients. Dr. Matthew Breen is featured in a two-part interview with Lee Arnold, Vice President of the AKC Canine Health
Dr. Breen Published in Journal of Chromosome Research
Cancer researchers at North Carolina State University and the University of Minnesota have found that humans and dogs share more than friendship and companionship – they also share the same genetic basis for certain types of cancer. Furthermore, the researchers say that because of the way the genomes have evolved, getting cancer may be inevitable
Dr. Breen Receives Research Award from AKC Canine Health Foundation
Matthew Breen, Professor of Genomics, is the 2007 recipient of the “Asa Mays, DVM, Excellence in Canine Health Research Award” presented by the American Kennel Club Canine Health Foundation (CHF). Named to honor the memory of longtime breeder and veterinarian Dr. Asa Mays, the award recognizes an individual researcher who, according to the CHF board