Yogesh Saini

Bio

Lab Website

Dr. Saini received his DVM (1996-2001) from College of Veterinary Sciences, Palampur (India) and MVSc in Veterinary Biochemistry and Biotechnology (2001-2003) from College of Veterinary Sciences, Pantnager (India). Thereafter, he completed a Senior Research Fellowship (2003-2005) at Indian Veterinary Research Institute, Izatnagar (India). He received a dual-PhD (Genetics and Toxicology) under the supervision of Dr. John LaPres at Michigan State University in 2009. After completing postdoctoral training (2010-2014) in the laboratory of Dr. Richard Boucher at the University of North Carolina (UNC), he was promoted to the rank of research instructor at Marsico Lung Institute. He then joined LSU/SVM in 2014 as a tenure-track Assistant Professor. In 2019, he received early tenure with promotion to Associate Professor. Most recently in August 2023, he joined NCSU/CVM as full professor in the department of Population Health and Pathobiology.

Area(s) of Expertise

Lung Inflammation, Macrophage Biology, Inhalation Toxicology, Hepatotoxicity

Publications

• Acute and Repeated Ozone Exposures Differentially Affect Circadian Clock Gene Expression in Mice. , Advanced biology (2023)
• Airway epithelial cell-specific deletion of HMGB1 exaggerates inflammatory responses in mice with muco-obstructive airway disease. , Frontiers in immunology (2023)
• Activating transcription factor 6 protects against endothelial barrier dysfunction. , Cellular signalling (2022)
• Case report: Mafb promoter activity may define the alveolar macrophage dichotomy. , Frontiers in immunology (2022)
• Higher susceptibility of males to bleomycin-induced pulmonary inflammation is associated with sex-specific transcriptomic differences in myeloid cells. , Toxicology and applied pharmacology (2022)
• In Vitro Screening Method for Characterization of Macrophage Activation Responses. , Methods and protocols (2022)
• Induction of whole-body gene deletion via R26-regulated tamoxifen-inducible Cre recombinase activity. , Frontiers in pharmacology (2022)
• NLRP3 inflammasome is dispensable in methicillin resistantStaphylococcus aureusurinary tract infection , (2022)
• Ozone exposure upregulates the expression of host susceptibility protein TMPRSS2 to SARS-CoV-2. , Scientific reports (2022)
• Silencing of RNA binding protein, ZFP36L1, promotes epithelial-mesenchymal transition in liver cancer cells by regulating transcription factor ZEB2. , Cellular signalling (2022)

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