Anemia Associated With Chronic Kidney Disease (CKD) In Cats

Principle Investigator Autumn N. Harris and Shelly Vaden Description Chronic kidney disease (CKD) affects many older cats and can lead to anemia, a condition in which the body does not produce enough red blood cells. Anemia can contribute to decreased energy, weakness, reduced appetite, and a lower quality of life. Currently, treatment options for cats…

CARE- Feline HCM Stage C

Principle Investigator Joshua Stern Description The objective of this study is to evaluate the safety and efficacy of this investigational product in cats diagnosed with hypertrophic cardiomyopathy (HCM) or hypertrophic obstructive cardiomyopathy (HOCM) following their first onset of congestive heart failure (CHF). Specifically, the study aims to determine whether treatment with the investigational product can…

Feline Heart Health

Principle Investigator Joshua Stern Description The Stern Lab at NC State is looking for cats of all ages and breeds without previously diagnosed cardiovascular disease to join a heart health study. Testing Requirements Participating cats will come to NCSU for an advanced cardiac evaluation including: Heart ultrasound Complete blood Blood Pressure Blood test for markers…

Observation of Feeding Practices in Privately Owned Cats with Chronic Kidney Disease (CKD): A Pilot Study

Principle Investigator Dr. Autumn Harris Description Nutritional management is a cornerstone of care for cats with chronic kidney disease (CKD), yet accurately assessing what cats consume in the home environment remains a significant challenge. Cats are often inconsistent eaters, and discrepancies frequently exist between the amount of food offered and the amount actually consumed. This…

CATNIP: Evaluation of Comprehensive Assessment Techniques and Novel Indicators of Progression in Feline CKD Study.

Principle Investigator Autumn N. Harris and Shelly Vaden Description The objective of this study is to evaluate novel technology indicators of CKD progression in cats. This evaluation will include cats with Stage 2 or Stage 3 CKD, as well as healthy non-CKD controls. Your veterinarian will determine if your cat is eligible for study and…

Become a Feline Cancer Hero

Principle Investigator Dr. Yea Ji Jeong Description What is the Legacy Tissue Donation Program?• Patients’ family agree to donate tumor/metastases tissue after death • High quality biospecimens are obtained for cancer research (1-2 hours after death)• A board-certified veterinary anatomic pathologist supervises collection of only the necessary tumor and metastatic tissue.• Samples are analyzed for…

Radiation Therapy for Feline Chronic Gingivostomatitis (FCGS)

Principle Investigator Dr. Yen-Hao Lai Description NC State College of Veterinary Medicine is recruiting cats with chronic gingivostomatitis to explore if radiation therapy could serve as an effective treatment option. Testing Requirements Participation:~ You will be required to bring your cat to NC State Veterinary Hospital for a total of 9 studyvisits:~ 1 screening visits~…

PIVOT-C: Pilot Intratumoral Vaccine Therapy For Oral Tumors in Cats

Principle Investigator Dr. Joanne Intile Description This study investigates the safety and potential benefits of injecting a commonly used feline vaccine (FVRCP) directly into tumors. The goal is to gain a deeper understanding of the feasibility of intratumoral injection for treatment and how this approach may affect the tumor environment and stimulate an anti-tumor immune…

Efficacy of Potassium Citrate as a Treatment for Metabolic Acidosis in Cats with Chronic Kidney Disease

Principle Investigators Autumn N. Harris and Shelly Vaden Description Chronic Kidney Disease (CKD) is defined as the presence of functional abnormalities in one or both kidneys over a prolonged period of time. CKD is the most common typeof kidney disease and management has largely been focused on supportive and symptomatic therapy, with very few new…

Effect of Iron Supplementation on the response to Varenzin-CA1 in Cats with CKD and Anemia

Principle Investigators Autumn N. Harris and Shelly Vaden Description Anemia is common in feline chronic kidney disease (CKD) and several options are available for treatment including the medication Varenzin CA-1 ® . Iron supplementation is an important part of the treatment of anemia in some patients with CKD and is given as standard of care…

A Blinded, Randomized, and Placebo-Controlled Clinical Trial of a Novel Veterinary Product for the Management of Chronic Kidney Disease in Cats

Principle Investigator Dr. Autumn Harris Description Evidence exists to suggest that aging of the kidney may contribute to the onset and progression of chronic kidney disease (CKD). Rapamycin is a drug that is a known modulator of the aging process and additionally may decrease the formation of fibrosis (scarring) in the kidney. A feline formulation…

Ammonia Excretion, A Novel Biomarker and Therapeutic Target for Feline CKD

Principle Investigator Dr. Harris Description Chronic Kidney Disease (CKD) is defined as the presence of functional abnormalities in one or both kidneys over a prolonged period of time. Serum creatinine is currently used as a marker of kidney function, but it cannot detect early changes in kidney function. Detecting CKD early has significant importance because…

Feline Congestive Heart Failure and Coagulation

Principle Investigator Teresa DeFrancesco Description Cats with congestive heart failure (abnormal fluid accumulation) are at high risk for developing blood clots but the risk appears to differ with the manifestation of heart failure. There are two different manifestations of congestive heart failure in cats: 1) primarily pulmonary edema, and 2) primarily pleural effusion. Pulmonary edema…