Bruce Keene

Bio

I am a clinician, educator, and researcher in veterinary and comparative cardiology. My expertise is in the diagnosis and interventional and medical management of congenital and acquired heart diseases of animals.
Link to publications: https://www.ncbi.nlm.nih.gov/pubmed/?term=Keene+B

AFFILIATIONS

American College of Veterinary Internal Medicine, American Society of Echocardiography, Adjunct Professor of Cardiology, Department of Pediatrics, Duke University

CERTIFICATIONS

Diplomate, American College of Veterinary Internal Medicine (Cardiology)

Area(s) of Expertise

SPONTANEOUS ANIMAL DISEASE MODELS
My research is focused on the design and performance of clinical trials that test the safety and efficacy of new medications or minimally invasive interventions potentially useful in the management of spontaneous heart diseases of dogs and cats.

Publications

• Association of diet with clinical outcomes in dogs with dilated cardiomyopathy and congestive heart failure* , JOURNAL OF VETERINARY CARDIOLOGY (2022)
• A deleterious mutation in the ALMS1 gene in a naturally occurring model of hypertrophic cardiomyopathy in the Sphynx cat , ORPHANET JOURNAL OF RARE DISEASES (2021)
• Absence of known feline MYH7 and MYBPC3 variants in a diverse cohort of cats with hypertrophic cardiomyopathy , ANIMAL GENETICS (2021)
• Letter to the editor regarding "Efficacy of adding ramipril (VAsotop) to the combination of furosemide (Lasix) and pimobendan (VEtmedin) in dogs with mitral valve degeneration: The VALVE trial" , JOURNAL OF VETERINARY INTERNAL MEDICINE (2021)
• Myxomatous mitral valve disease in Miniature Schnauzers and Yorkshire Terriers: 134 cases (2007-2016) , JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION (2021)
• Use of whole genome analysis to identify shared genomic variants across breeds in canine mitral valve disease , HUMAN GENETICS (2021)
• What Is Your Diagnosis? , JOURNAL OF AVIAN MEDICINE AND SURGERY (2021)
• Atenolol in cats with subclinical hypertrophic cardiomyopathy: a double-blind, placebo-controlled, randomized clinical trial of effect on quality of life, activity, and cardiac biomarkers , JOURNAL OF VETERINARY CARDIOLOGY (2020)
• Clinical presentation, cardiovascular findings, etiology, and outcome of myocarditis in dogs: 64 cases with presumptive antemortem diagnosis (26 confirmed postmortem) and 137 cases with postmortem diagnosis only (2004-2017) , JOURNAL OF VETERINARY CARDIOLOGY (2020)
• Renin-angiotensin aldosterone profile before and after angiotensin-converting enzyme-inhibitor administration in dogs with angiotensin-converting enzyme gene polymorphism , JOURNAL OF VETERINARY INTERNAL MEDICINE (2020)

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