NC State College of Veterinary Medicine is proud to host the sixth international Veterinary Pain Short Course on pain, pain mechanisms and novel therapies in veterinary medicine, April 22 – 24, 2021. This years program has gone virtual. This meeting is unique in veterinary medicine for its emphasis upon fundamental (basic) principles and mechanisms of pain as they pertain to the veterinary patient.
Pain in the veterinary patient is a rich and complex phenomenon. The development of therapeutics to manage that pain state has been a subject of great interest, and advances in therapeutics reflects upon the growth in our understanding of the basic mechanisms in pain processing.
Interest in pain and its management is a natural focus of the veterinary profession as mandated by the AVMA and the standards set by the AAHA/AAFP and practiced by the International Veterinary Association for Pain Management (IVAPM).
Vet Pain is unique for a detailed emphasis upon fundamental principles and mechanisms of pain as they pertain to the veterinary patient.
Course consists of lectures with comprehensive lecture handouts and representative papers
This program has been approved for 8.5 hours of continuing education credit in jurisdictions that recognize RACE approval.
This course was designed for veterinarians and animal researchers interested in the study of pain in animals and humans and for pharmaceutical researchers and companies interested in the development of veterinary analgesics.
|11:00 - 11:10am||Introductory remarks||Duncan Lascelles|
|11:10am - 12:00pm||Over view of recent advances in basic understanding of pain signaling||Tony Yaksh|
|12:00 - 12:15pm||Break|
|12:15 - 1:00pm||Over view of recent advances in basic understanding of pain signaling pt 2||Tony Yaksh|
|1:00 - 1:30pm||Q&A|
|1:30 - 2:00pm||State of pain and pain management in vet practice||Mark Epstein
|2:00 - 2:30pm||Open Discussion|
|Neuroinflammation in Pain Processing: Mechanisms|
|11:00am - 12:00pm||Role of innate and adaptive immunity in RA and OA||Camilla Svensson|
|12:00 - 12:10pm||Break|
|12:10 - 1:00pm||Role of Glia in neuroinflammation and chronic pain||Ru-Rong Ji|
|1:00 - 1:10pm||Break|
|1:10 - 2:00pm||Immune cells (Macrophages and Lymphocytes) in nociceptive processing||Robert Sorge|
|2:00 - 2:30pm||Open Discussion|
|Therapeutic interventions that target inflammatory signaling|
|11:00 - 11:10am||Introduction|
|11:10am - 12:00pm||Introduction – Platforms for delivering anti-neuroinflammatory therapies||Tony Yaksh|
|12:00 - 12:10pm||Break|
|12:10 - 1:00||Neuraxial IL10 and therapeutic approaches using AAV||Andreas Beutler|
|1:00 - 1:10pm||Break|
|1:10 - 2:00pm||Targeted Toxins: Capsaicin and Resinferatoxin:||Mike Iadarola|
|2:00 - 2:30pm||Open Discussion and Future Plans|
|NC Vet Pain 2020 Speakers|
|Andreas Beutler M.D., PhD
CEO, Interventional AnalgesiX Inc.
|Dr. Beutler is the Founder and CEO of Interventional AnalgesiX Inc. (IAX), a preclinical-stage biotech startup company developing non-addictive analgesics for hitherto intractable chronic pain. Dr. Beutler has authored >50 scientific publications (including in PNAS, JCI, Ann. Neurol., Nature Genetics). As a Principal Investigator, he has been continuously supported by research grants from the National Institutes of Health (NIH) from 2003 to the present, with currently active funding (as of 2019) by an SBIR grant (2019-2020) and an R01 grant (2017-2022) from the National Institutes of Neurological Disorders and Stroke (NINDS).|
|Mark Epstein, DVM, DABVP, CVPP
Co-owner and Medical Director at TotalBond Veterinary Hospital at Forestbrook
|Dr. Epstein received his DVM from University of Georgia and is the Senior Partner and Medical Director of TotalBond Veterinary Hospitals and Carolinas Animal Pain Management, a small group of AAHA-accredited practices in the Charlotte & Gastonia NC area that received the Small Business of the Year Award from the Gaston Regional Chamber of Commerce in 2015. He is a Diplomate of the American Board of Veterinary Practitioners (Canine/Feline) and is a past-president of ABVP. He is certified by the American Academy of Pain Management, is recognized as a Certified Veterinary Pain Practitioner (CVPP) by the International Veterinary Academy of Pain Management and is a past-president of IVAPM. Dr. Epstein chaired the AAHA Senior Care Guidelines Task Force and co-Chaired the 2015 AAHA/AAFP Pain Management Guidelines Task Force. He, is published in journals and textbooks, is a national and international lecturer on the recognition, prevention, and treatment of pain in the veterinary clinical setting.|
|Mike Iadarola PhD
Senior Research Scientist
Department of Perioperative Medicine
National Institutes of Health
|Dr. Michael J. Iadarola graduated from American University and obtained a Ph.D. in pharmacology from Georgetown University. Postdoctoral studies in neuroscience followed at Duke University.
Dr. Iadarola investigates the molecular and physiological mechanisms of pain transmission and control. His investigations focus on translational approaches to new pain treatments and on the fundamental molecular biology of pain sensing neurons and their response to acute and persistent pain
|Ru-Rong Ji, PhD
Professor of Anesthesiology, Duke University
|Ru-Rong Ji, PhD, is the chief of pain research within Duke Anesthesiology, co-director of the Center for Translational Pain Medicine, and a professor of anesthesiology and neurobiology. As director of the Sensory Plasticity and Pain Research Laboratory at Duke, his research focuses on molecular and cellular mechanisms of chronic pain, such as inflammatory pain, neuropathic pain, and cancer pain. He is internationally-recognized for his contributions to demonstrating critical roles of MAP kinase signaling pathways and glial cells in the pathogenesis of chronic pain. His recent work has demonstrated powerful antinociceptive actions of pro-resolution lipid mediators (e.g., resolvins). Ji lectures internationally and reviews papers for numerous international journals. He also serves on National Institutes of Health review panels and the editorial boards of Pain, Neuroscience, and Neuroscience Bulletin. He previously was an associate professor at Brigham and Women’s Hospital, Harvard Medical School, before joining the Duke faculty in 2012. He earned a PhD in neurobiology at Shanghai Institute of Physiology and completed postdoctoral training at Peking (Beijing) University Medical School, Karolinska Institute, and Johns Hopkins University School of Medicine.|
|Jennifer F. Johnson VMD, CVPP
President, International Veterinary Academy of Pain Management www.IVAPM.org
|A Philadelphia native, Dr. Johnson worked as an associate veterinarian for 14 years before owning and operating Stoney Creek Veterinary Hospital in Morton, PA, for 10 years. During her tenure as practice owner, the hospital grew from a 2-doctor practice to employ 6 veterinarians and 45 team members, emphasizing preventative care and personalized family medicine.
Pain management has always been a priority in her practice. Her special interest is the use of therapeutic laser for the treatment of pain. In 2012, she achieved Certified Veterinary Pain Practitioner (CVPP) qualification through the International Veterinary Academy of Pain Management (IVAPM). Now relocated to Arizona and a full-time educator, Dr. Johnson speaks nationally on pain management, laser therapy and digital thermal imaging, stressing the importance of pain identification in general practice. She recently authored the chapter on pain management for Laser Therapy in Veterinary Medicine, published in 2017. Dr. Johnson serves on the board of the IVAPM, currently as President-elect and is also a board member of eagleYcondor, providing children’s education and high volume spay/neuter and medical care for animals in poor communities in Ecuador.
|Duncan Lascelles BSc, BVSc, PhD, FRCVS, CertVA, DSAS(ST), DECVS, DACVS
Professor of Translational Pain Research and Management.NC State College of Veterinary Medicine
|Dr Lascelles is director of the Comparative Pain Research and Education Centre (CPREC). His research program (Translational Research in Pain [TRiP]) is dedicated to answering critical questions about pain control and pain mechanisms through high quality, innovative research. His career has been focused on developing algometry methods (methods to measure pain) in spontaneous disease animal models (pets with naturally occurring disease), and probing tissues from well-phenotyped animals with spontaneous disease to understand the neurobiology, with a strong translational focus. The aim of his research is to improve pain control in companion animals, and facilitate analgesic development in human medicine. He has authored over 180 peer reviewed research papers and reviews and 190 research abstracts, as well as over 30 book chapters.|
|Kristen Messenger DVM, PhD, DACVAA, DACVCP
Assistant Professor of Pharmacology at North Carolina State University, College of Veterinary Medicine
|Kristen Messenger is an Assistant Professor of Pharmacology at North Carolina State University. She is board-certified in both anesthesia and clinical pharmacology and currently works with each of these specialty services at NCSU. Dr. Messenger’s research interests are in the pharmacokinetics and pharmacodynamics of analgesic and anesthetic drugs, with a special focus on NSAIDS and opioids in companion animals.|
|William Muir DVM, PhD, DACVAA, DACVECC
Q Test Labs"
|Dr. Muir served as Professor and Director of Anesthesiology and Pain Management at The Ohio State University College of Veterinary Medicine (1970-2007), as the research director for the US based Research Medications and Testing Consortium (RMTC) for 2 years (2007-2009), and as the Chief Medical Officer for the Animal Medical Center in New York City (2009-2012). He currently is a Professor of physiology in the College of Veterinary Medicine at Lincoln Memorial University in Harrogate TN, and Scientific Advisor for QTest laboratories (preclinical research facility) in Columbus OH.|
|Robert Sorge BSCc, MA, PhD
Department of Psychology
University of Alabama at Birmingham
|Dr. Sorge is primarily interested in the ways in which the immune system modulates pain and ways that we can utilize the immune system to reduce pain. His work has uncovered a sex difference in the immune cell involvement in maintenance of chronic pain in rodents. Currently, his lab is focused on the ways in which diets alter immune system activity and the subsequent effects on pain and recovery from injury. His lab has developed both a model Standard American Diet and an Anti-Inflammatory diet to be used as an intervention for chronic pain. Additionally, Dr. Sorge has translated his preclinical work to clinical patients wherein prescribed diets can reduce pain. Dr. Sorge is a Rita Allen Foundation Scholar and has received funding for his work through the American Pain Society, International Association for the Study of Pain and the Rita Allen Foundation. Dr. Sorge earned his bachelor’s degree at McMaster University, his Master’s at Wilfrid Laurier University and his PhD at Concordia University. After two postdoctoral fellowships at McGill University, he joined the Department of Psychology at the University of Alabama at Birmingham in 2012 as an Assistant Professor.|
|Camilla Svensson MS, PhD
Department of Physiology and Pharmacology
Karolinska Institutet, Stockholm, Sweden
|Professor Svensson obtained her PhD at UC San Diego, where she also held a postdoctoral research position at the Department of Medicine. She subsequently moved on to Karolinska Institute, Stockholm, Sweden, where she today holds a position as Associate Professor and research group leader for Molecular Pain research at the Department of Physiology and Pharmacology. Her research is focused on investigating the role of neuroinflammation in the peripheral and central nervous system, with particular focus on pain mechanisms in conditions with joint inflammation and autoimmunity, such as rheumatoid arthritis.|
|Tony Yaksh, PhD
Distinguished Professor of Anesthesiology and Pharmacology
University of California, San Diego
La Jolla, CA
|Dr. Yaksh joined UCSD in 1988 as Professor and Vice Chairman for Research in the Department of Anesthesiology and Professor of Pharmacology. Dr. Yaksh's research interests are primarily in the area of the biology of pain processing, with a particular interest in the role of non-neuronal cells and lipid mediators in pain transmission. He is an expert on issues related to spinal drug kinetics and the evaluation of the safety of spinally delivered agents. He has published more than 800 papers with 46,000 citations in >26,000 papers and edited 6 texts and is working on a 7th. He has been a mentor to more than 150 post-graduate Fellows. He has been funded consistently by the NIH since 1977 and has twice been a Jacob Javitz award recipient. He is currently the Principal Investigator on several NIH grants and numerous contracts. He has received honors and awards, including the FWL Kerr award of the American Pain Society, the American Society of Anesthesiology (ASA) Award for Excellence in Research, the Rovenstein award from the New York Society of Anesthesiology, and the Torsten Gordh award from the Swedish Society of Medicine.|
There will be no fee for registration. The costs of holding this virtual event will be covered by the Comparative Pain Research and Education Center, and sponsorship monies. However, participants will need to register prior to the meeting:
Thank you to our Sponsors