Clinical Trials: Horses

July 16, 2025

Endocrine diseases assessment in horses

Principle Investigator Katarzyna Dembek Description Equine metabolic diseases are disorders that affect a horse’s metabolism, often leading to abnormal hormone function. The most common are Equine Metabolic Syndrome (EMS), linked to obesity and insulin resistance, and Pituitary Pars Intermedia Dysfunction (PPID), a condition affecting older horses due to pituitary gland dysfunction. These diseases increase the…

July 16, 2025

Short-term antimicrobial therapy for the treatment of mild to moderate bacterial pneumonia in adult horses

Principle Investigator Kate Hepworth-Warren Description Bacterial pneumonia is a common condition in horses that most often develops after long distance transportation, viral infections, or esophageal obstruction (choke). It can lead to prolonged and expensive therapy with potential complications including sepsis, laminitis, and death. In humans and small animals with bacterial pneumonia, guidelines suggest treating with…

July 16, 2025

Identifying innovative therapeutic targets and developing novel treatments for neutrophil-mediated conditions across veterinary and human patients

Principle Investigator Rosemary Bayless Description The Bayless Lab at NC State College of Veterinary Medicine is enrolling healthy mare/foal pairs to evaluate neutrophil function from time of birth through 6 months of age. The study will consist of physical examination and blood collection from the foal and mare when the foal is 24 hours, 72…

July 03, 2025

TRAP-Paclitaxel for Equine Eyelid Squamous Cell Carcinoma

Principle Investigator Dr. Annie Oh Description This is a dose-escalation clinical trial to determine the effectiveness of a novel chemotherapeutic drug, TRAP-Paclitaxel, for the treatment of equine squamous cell carcinoma (SCC). The study will consist of an initial visit with biopsy, and 1-3 injections of TRAP-Paclitaxel at a minimum of 6 weeks apart. Horses will…