Neil McCarthy

Bio

Dr. McCarthy earned his PhD at the University of Texas at Austin in the Eberhart lab studying genetic predisposition in fetal alcohol spectrum disorder using zebrafish. He did his postdoctoral work in the Shivdasani lab at Dana-Farber Cancer Institute in Boston investigating mesenchymal-epithelial interactions driving stem cell homeostasis in the gut using mouse and in vitro organoids. As a new assistant professor in the Molecular Biomedical Sciences department, his lab will continue to study intestinal mesenchymal function in development, health, and disease.

Publications

• Graded BMP signaling within intestinal crypt architecture directs self-organization of the Wnt-secreting stem cell niche , Cell Stem Cell (2023)
• Role of PDGFRA+ cells and a CD55+ PDGFRALo fraction in the gastric mesenchymal niche , Nature Communications (2023)
• Smooth muscle contributes to the development and function of a layered intestinal stem cell niche , Developmental Cell (2023)
• Cellular and molecular architecture of the intestinal stem cell niche , Nature Cell Biology (2020)
• Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient , Cell Stem Cell (2020)
• Novel Ethanol‐Sensitive Mutants Identified in an F3 Forward Genetic Screen , Alcoholism: Clinical and Experimental Research (2019)
• An Fgf-Shh signaling hierarchy regulates early specification of the zebrafish skull , Developmental Biology (2016)
• Pdgfra and Pdgfrb genetically interact during craniofacial development , Developmental Dynamics (2016)
• Gene–ethanol interactions underlying fetal alcohol spectrum disorders , Cellular and Molecular Life Sciences (2014)
• A Screen of Zebrafish Mutants Identifies Ethanol‐Sensitive Genetic Loci , Alcoholism: Clinical and Experimental Research (2013)