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Ricardo G. Maggi, MS, PhD

Research Professor, Internal Medicine

Office: 919.513.8273
Lab: Vector Borne Disease Diagnostics
Lab Phone: 919.513.8279

Ph.D. –Chemistry-Molecular Microbiology - University of Puerto Rico, USA
MS. –Chemistry –University of Puerto Rico, USA
Licentiate in Chemistry – Proteomics-National University of Córdoba, Argentina
Global Health, Infectious Diseases
Molecular microbiology of vector borne diseases and intracellular pathogens in animals and humans.

Development of molecular assays for the detection, diagnosis, and characterization of emerging and re-emerging zoonotic pathogens.

Dr, Ricardo Maggi has a background in proteomics from Argentina, and in molecular microbiology of fastidious microorganisms from the University of Puerto Rico. Ricardo joined North Carolina State University College of Veterinary Medicine in 2005 as Research Assistant professor and became Research Associate Professor in 2012 focusing his research on vector-borne diseases. He became a Research Professor in 2020. He specializes in the design, development, and validation of in-vitro clinical diagnostic tests for the detection and characterization of emerging and re-emerging vector-borne pathogens in humans and animals.
During the last five years, his research focuses not only in the development of novel diagnostic serological, microbiological and molecular tests, but also the identification of prophylactic agents (vaccines), the characterization of mechanisms for microbial pathogenicity, and the development of diagnostic tests aimed at the identification of potential molecular markers for early detection of bacterial-induced cancers.
He has generated more than 120 peer-reviewed publications, lectured in several national and international scientific and clinical forums, and written over 7 book chapters pertaining to his research activities. His work has also lead to the creation of a North Carolina State University spinout biotech Company, Galaxy Diagnostics that provide CLIA diagnostic tests for the diagnosis of vector-borne pathogens in 48 States.

In addition to training of veterinary graduate students in his laboratory, he is actively involved in preparing undergraduate and graduate students for careers in clinical and basic research.
  • (2019) A review on the occurrence of companion vector-borne diseases in pet animals in Latin America.Maggi RG and Kramer F. 
 | P&V. 12:145. doi: 10.1186/s13071-019-3407-x.
  • (2018) Detection and prevalence of Babesia spp. in American black bears (Ursus americanus) from Eastern and Western North Carolina.Westmoreland LSH, Stoskopf MK, Sheppard E, DePerno CS, Gould NP, Olfenbuttel C, Maggi RG. | JWD. 10.7589/2018-06-164.
  • (2018) Regional prevalences of Borrelia burgdorferi, Borrelia bissettiae, and Bartonella henselae in Ixodes affinis, Ixodes pacificus and Ixodes scapularis in the USA.Maggi RG, Toliver M, Richardson T, Mather T, Breitschwerdt EB. | Ticks Tick Borne Dis. 10:360-364.
  • (2017) Detection and prevalence of four different hemotropic Mycoplasma spp. in Eastern North Carolina American black bears (Ursus americanus). Comparative Immunology, Microbiol. 
Westmoreland LSH, Stoskopf MK, Maggi RG. 
 | Infectious Diseases. 50:106-109.
  • (2017) Prevalence of Bartonella spp. by culture, PCR and serology, in veterinary personnel from Spain. 
Oteo JA, Maggi R, Portillo A, Bradley J, García-Álvarez L, San-Martín M, Roura X, Breitschwerdt E. 
 | Parasit Vectors. 10:13071-017-2483.
  • (2016) Molecular identification and bioinformatics analysis of a potential anti-vector vaccine candidate, 15-kDa salivary gland protein (Salp15), from Ixodes affinis ticks.Sultana H., Patel U., Toliver M, Maggi RG, Neelakanta G. | Ticks and Tick-borne diseases. 7:46-53.
  • (2016) Prevalence of Anaplasma phagocytophilum in North Carolina eastern black bears (Ursus americanus). 
Westmoreland, LSH; Stoskopf, MK; Maggi, RG. 
 | Journal of Wildlife Diseases. 52: 968-970.
  • (2016) Detection of Mycoplasma haemocanis, Mycoplasma haematoparvum, Mycoplasma suis and other vector-borne pathogens in dogs from Córdoba and Santa Fé, Argentina.Mascarelli PE, Tartara GP, Pereyra NB, Maggi RG. | Parasit Vectors. 9:642.
  • (2015) Infection with Bartonella henselae in a Danish Family.Maggi RG, Balakrishnan N, Bradley JM, Breitschwerdt EB. | J Clin Microbiol. 53:1556-1561.
  • (2015) Prevalence of Bartonella spp. in Canine Cutaneous Histiocytoma. 
Pultorak, EL; Linder, K; Maggi, RG; Balakrishnan, N; Breitschwerdt, EB. 
 | J Comp Pathol. 153:14-21
  • (2015) Vector-borne pathogens in arctic foxes, Vulpes lagopus, from Canada.Mascarelli PE, Elmore SA, Jenkins EJ, Alisauskas RT, Walsh M, Breitschwerdt BE, Maggi RG. | Research in Veterinary Science Journal. 99:58-59
  • (2014) Detection of Bartonella species in the blood of veterinarians and veterinary technicians: A newly recognized occupational hazard? 
Lantos P, Maggi RG, Ferguson B, Varkey J, Park LP, Breitschwerdt EB, Woods CW. 
 | Vector-Borne and Zoonotic Diseases. 14: 563-570
  • (2014) Novel Bartonella Infection in Northern and Southern Sea Otters (Enhydra lutris kenyoni and Enhydra lutris nereis). 
Carrasco SE, Chomel BB, Gill VA, Kasten RW, Maggi RG, Breitschwerdt EB, Byrne BA, Burek-Huntington KA, Miller MA, Goldstein T, Mazet JAK. 
 | Vet. Microbial. 170:325-334.
  • (2014) In Pursuit of a Stealth Pathogen: Laboratory Diagnosis of Bartonellosis.Wolf LA, Cherry NA, Maggi RG, Breitschwerdt EB. | Clinical Microbiology Newsletter. 36:33–39.
  • (2014) Comparison between serological and molecular panels for the diagnosis of vector-borne infectious diseases in dogs. 
Maggi RG, Birkenheuer AJ, Hegarty BC, Bradley JM, Levy MG, Breitschwerdt EB. 
 | Parasites and Vectors. 7:127
  • (2013) Infection with hemotropic Mycoplasma sp. in people with and without extensive arthropod and animal contact. 
Maggi RG, Compton SM, Trull CL, Mascarelli PE, Mozayeni BR, Breitschwerdt EB. 
 | J. Clin. Microbiol. 51:3237-3241
  • (2013) Co-infection with Anaplasma platys, Bartonella henselae and Candidatus Mycoplasma haematoparvum in a veterinarian. 
Maggi RG, Mascarelli PE, Havenga LN, Naidoo V, Breitschwerdt EB. 
 | Parasites and Vectors. 6:98
  • (2013) Novel Hemotropic Mycoplasma species in White-tailed Deer (Odocoileus virginianus). 
Maggi RG, Chitwood MC, Kennedy-Stoskopf S, DePerno CS. 
 | Comparative Immunology, Microbiology & Infectious Diseases. 36:607-611
  • (2013) Serial testing from a three-day collection period using the BAPGM platform may enhance the sensitivity of Bartonella spp. detection in bacteremic human patients. 
Pultorak EL, Maggi RG, Mascarelli PE, Breitschwerdt EB. 
 | J Clin Microbiol. 51: 1673-1677
  • (2013) ‘Ca. Mycoplasma haemomacaque’ and Bartonella quintana bacteremia in cynomolgus monkeys. 
Maggi RG, Mascarelli PM, Balakrishnan N, Rohde CM, Kelly CM, Ramaiah L, Leach MW, Breitschwerdt EB. 
 | JCM. 51:1408-1411.
  • (2013) Novel Hemotropic Mycoplasma species in White-tailed Deer (Odocoileus virginianus).Maggi RG, Chitwood MC, Kennedy-Stoskopf S, DePerno CS. | Comp Immunol Microbiol Infect Dis 2013 Dec;36(6):607-11. Epub 2013 Aug 22.
  • (2013) Infection with hemotropic mycoplasma species in patients with and without extensive arthropod and animal contact.Maggi RG, Compton SM, Trull CL, Mascarelli PE, Mozayeni BR, Breitschwerdt EB. | J Clin Microbiol 2013 Oct; 51(10):3237-3241.
  • (2013) Co-infection with Anaplasma platys, Bartonella henselae and Candidatus Mycoplasma haematoparvum in a veterinarian.Maggi RG, Mascarelli PE, Havenga LN, Naidoo V, Breitschwerdt EB. | Parasit Vectors 2013 Apr 15;6:103.
  • (2013) Bartonella henselae bacteremia in a mother and son potentially associated with tick exposure.Maggi RG, Ericson M, Mascarelli PE, Bradley JM, Breitschwerdt EB. | Parasit Vectors 2013 Apr 15;6:101.
  • (2012) Bartonella spp. bacteremia and rheumatic symptoms in patients from a Lyme disease-endemic region.Maggi RG, Mozayeni BR, Pultorak EL, Hegarty BC, Bradley JM, Correa, Breitschwerdt EB. | Emerg Infect Dis 2012 May;18(5):783-91.
  • (2011) Bartonella spp. bacteremia in high-risk immunocompetent patients.Maggi RG, Mascarelli PE, Pultorak EL, Hegarty BC, Bradley JM,, Mozayeni BR, Breitschwerdt EB. | Diagn Microbiol Infect Dis 2011 Dec; 71(4): 430-437. Epub 2011 Oct 13.
  • (2011) Rickettsia rickettsii transmission by a lone star tick, North Carolina.Breitschwerdt EB, Hegarty BC, Maggi RG, Lantos PM, Aslett DM, Bradley JM. | Emerg Infect Dis 2011 May;17(5):873-5.
  • (2010) Borrelia species in Ixodes affinis and Ixodes scapularis ticks collected from the coastal plain of North Carolina.Maggi RG, Reichelt S, Toliver M, Engber B. | Ticks Tick Borne Dis 2010 Dec; 1(4): 168-171. Epub 2010 Oct 20.
  • (2010) Molecular evidence of perinatal transmission of Bartonella vinsonii subsp. berkhoffii and Bartonella henselae to a child.Breitschwerdt EB, Maggi EG, Farmer P, Mascarelli PE. | J Clin Microbiol 2010 Jun;48(6):2289-93. Epub 2010 Apr 14.
  • (2010) Suspected needle stick transmission of Bartonella vinsonii subspecies berkhoffii to a veterinarian.Oliveira AM, Maggi RG, Woods CW, Breitschwerdt EB. | J Vet Intern Med 2010 Sep-Oct;24(5):1229-32. Epub 2010 Jul 28.
  • (2010) Comparative activity of pradofloxacin, enrofloxacin and azithromycin against Bartonella henselae isolates collected from cats and a human.Biswas S, Maggi RG, Papich MG, Keil D, Breitschwerdt EB. | J Clin Microbiol 2010 Feb;48(2):617-8. Epub 2009 Dec 9.
  • (2010) Molecular mechansims of Bartonella henselae resistance to azithromycin, pradofloxacin and enrofloxacin.Biswas S, Maggi RG, Papich MG, Breitschwerdt EB. | J Antimicrob Chemother 2010 Mar;65(3):581-2. Epub 2009 Dec 18.
  • (2010) Bartonella vinsonii subsp. berkhoffii and Bartonella henselae bacteremia in a father and daughter with neurological disease.Breitschwerdt EB, Maggi RG, Lantos PM, Woods CW, Hegarty BC, Bradley JM. | Parasit Vectors 2010 Apr 8;3(1):29.
  • (2010) PCR amplification of Bartonella koehlerae from human blood and enrichment blood cultures.Breitschwerdt EB, Maggi RG, Mozayeni BR, Hegarty BC, Bradley JM, Mascarelli PE. | Parasit Vectors 2010 Aug 24;3:76.
  • (2009) Bartonella endocarditis: a pathology shared by animal reservoirs and patients.Chomel BB, Kasten RW, Williams C, Wey AC, Henn JB, Maggi R, Carrasco S, Mazet J, Boulouis HJ, Maillard R, Breitschwerdt EB. | Ann NY Acad Sci 2009 May; 1166:120–126.
  • (2009) Isolation of Candidatus Bartonella melophagi from human blood.Maggi RG, Kosoy M, Mintzer M, Breitschwerdt EB. | Emerging Inf. Dis. 2009 Jan; 15(1):66-68.
  • (2009) Isolation of Bartonella vinsonii subsp. berkhoffii genotype II from a boy with epithelioid hemangioendothelioma and a dog with hemangiopericytoma.Breitschwerdt EB, Maggi RG, Varanat M, Linder KE, Weinberg G. | J Clin Microbiol 2009 Jun;47(6):1957-60. Epub 2009 Apr 15.
  • (2009) A groundhog, a novel Bartonella sequence, and my father’s death.Breitschwerdt EB, Maggi RG, Cadenas MB, de Paiva Diniz PP. | Emerg Infect Dis 2009 Dec;15(12):2080-6.
  • (2009) A confusing case of canine vector-borne disease: clinical signs and progression in a dog co-infected with Ehrlichia canis and Bartonella vinsonii subsp. berkhoffii.Breitschwerdt EB, Maggi RG. | Parasit Vectors 2009 Mar 26;2 Suppl 1:S3.
  • (2009) Use of broad range 16S rDNA PCR in clinical microbiology.Sontakke S, Cadenas MB, Maggi RG, Diniz PP, Breitschwerdt EB. | J Microbiol Methods 2009 Mar;76(3):217-25. Epub 2008 Nov 21.
  • (2009) Comparative medical features of canine and human bartonellosis.Breitschwerdt EB, Maggi RG. | Clin Microbiol Infect 2009 Dec;15 Suppl 2:106-7. Epub 2009 Apr 30.
  • (2008) Bartonella henselae in captive and hunter harvested beluga (Delphinapterus leucas).Maggi RG, Raverty SA, Lester SJ, Huff DG, Haulena M, Ford SL, Nielsen O, Robinson JH, Breitschwerdt EB. | J Wildl Dis 2008 Oct; 44(4): 871-877.
  • (2008) Bartonella sp. bacteremia in patients with neurological and neurocognitive dysfunction.Breitschwerdt EB, Maggi RG, Nicholson WL, Cherry NA, Woods CW. | J Clin Microbiol 2008 Sep;46(9):2856-61. Epub 2008 Jul 16.
  • (2008) Detection of Bartonella henselae in the blood of two adult horses.Jones SL, Maggi RG, Shuler J, Alward A, Breitschwerdt EB. | J Vet Intern Med 22:495-498; 2008.
  • (2008) Bartonella species detection in captive, stranded and free-ranging cetaceans.Harms CA, Maggi RG, Breitschwerdt EB, Clemons-Chevis CL, Solangi M, Rotstein DS, Fair PA, Hansen LJ, Hohn AA, Lovewell GN, McLellan WA, Pabst DA, Rowles TK, Schwacke LH, Townsend FI, Wells RS. | Vet Res 39:59:00
  • (2007) Use of an insect cell culture growth medium to isolate bacteria from horses with effusive, fibrinous pericarditis: a preliminary study. Jones SL, Valenzisi A, Sontakke S, Sprayberry KA, Maggi R, Hegarty B, Breitschwerdt EB.  | Vet Microbiol 121:177-181.
  • (2006) A Bartonella vinsonii berkhoffii typing scheme based upon 16S-23S ITS and Pap31 sequences from dog, coyote, gray fox, and human isolates.Maggi RG, Chomel B, Hegarty BC, Jenn J, Breitschwerdt EB. | Mol Cell Probes 2006 Apr; 20(2): 128-134. Epub 2006 Feb 7.
  • (2005) Bartonella henselae in porpoise blood.Maggi RG, Harms CA, Hohn AA, Pabst DA, McLellan WA, Walton WJ, Rotstein DS, Breitschwerdt EB. | Emerg Infect Dis 2005 Dec; 11(12):1894-1898.
  • (2005) Isolation of bacteriophages from Bartonella vinsonii subsp. berkhoffii and the characterization of Pap31 gene sequences from bacterial and phage DNA.Maggi RG, Breitschwerdt EB. | J Mol Microbiol Biotechnol 2005; 9(1):44-51.
  • (2005) Potential limitations of the 16S-23S rRNA intergenic region for molecular detection of Bartonella species.Maggi RG, Breitschwerdt EB. | J Clin Microbiol 2005 Mar; 43(3):1171-1176.
  • (2005) Novel chemically modified liquid medium that will support the growth of seven bartonella species.Maggi RG, Duncan AB, Breitschwerdt EB. | J Clin Microbiol 2005 Jun;43(6):2651-5.