Yogesh Saini

Bio

Lab Website

Dr. Saini received his DVM (1996-2001) from College of Veterinary Sciences, Palampur (India) and MVSc in Veterinary Biochemistry and Biotechnology (2001-2003) from College of Veterinary Sciences, Pantnager (India). Thereafter, he completed a Senior Research Fellowship (2003-2005) at Indian Veterinary Research Institute, Izatnagar (India). He received a dual-PhD (Genetics and Toxicology) under the supervision of Dr. John LaPres at Michigan State University in 2009. After completing postdoctoral training (2010-2014) in the laboratory of Dr. Richard Boucher at the University of North Carolina (UNC), he was promoted to the rank of research instructor at Marsico Lung Institute. He then joined LSU/SVM in 2014 as a tenure-track Assistant Professor. In 2019, he received early tenure with promotion to Associate Professor. Most recently in August 2023, he joined NCSU/CVM as full professor in the department of Population Health and Pathobiology.

Area(s) of Expertise

Lung Inflammation, Macrophage Biology, Inhalation Toxicology, Hepatotoxicity

Publications

• Airspaces-derived exosomes contain disease-relevant protein signatures in a mouse model of cystic fibrosis (CF)-like mucoinflammatory lung disease , FRONTIERS IN PHARMACOLOGY (2024)
• Cell-Specific Contribution of IL4 Receptor α Signaling Shapes the Overall Manifestation of Allergic Airway Disease. , American journal of respiratory cell and molecular biology (2024)
• Net-Shaped DNA Nanostructures Designed for Rapid/Sensitive Detection and Potential Inhibition of the SARS-CoV-2 Virus , Journal of the American Chemical Society (2024)
• The NLRP3 Inflammasome Is Dispensable in Methicillin-Resistant Staphylococcus aureus Urinary Tract Infection , PATHOGENS (2024)
• Acute and Repeated Ozone Exposures Differentially Affect Circadian Clock Gene Expression in Mice. , Advanced biology (2023)
• Airway epithelial cell-specific deletion of HMGB1 exaggerates inflammatory responses in mice with muco-obstructive airway disease. , Frontiers in immunology (2023)
• Caveolin-1-derived peptide attenuates cigarette smoke-induced airway and alveolar epithelial injury. , American journal of physiology. Lung cellular and molecular physiology (2023)
• Activating transcription factor 6 protects against endothelial barrier dysfunction. , Cellular signalling (2022)
• Case report: Mafb promoter activity may define the alveolar macrophage dichotomy. , Frontiers in immunology (2022)
• Diagnostic Veterinary Pathology and its relevance to animal and human health. , Current Scenario and Future Challenges of Animal Health and Production in the North-Western Himalayan Region (2022)

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