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CORONAVIRUS UPDATE: The NC State Veterinary Hospital is seeing emergency and urgent cases only.

Veterinary Hospital Changes Reduce Risk While Continuing Care

Diagnostic Testing Lab
Department of Population Health and Pathobiology


Lab Contact:    919.513.6390  |     919.513.6703

Surgical Pathology Service shipping address:
1060 William Moore Dr. Room B104H, Raleigh, NC 27607

Shipping Information


With changes limiting visitors on campus for social distancing, the Surgical Pathology Service is no longer able to accept drop-off samples at the Emergency or Health and Wellness entrances. For local referring clinics which previously dropped off in these locations, we recommend the use of a shipping carrier with tracking services. Use of a courier service is permitted with delivery to the shipping and receiving dock only.

The Histology Laboratory located in the College of Veterinary Medicine at NC State University is a full service laboratory specializing in animal tissues. The laboratory occupies 1300 square feet of Lab spaces and an additional 500 feet of archival space. We provide paraffin embedment and microtomy, frozen sectioning, special staining, immunohistochemistry and glycol methacrylate embedment processing for all species of animals. In conjunction with the Anatomic Pathology group, we provide advanced diagnostic services to the CVM teaching hospital, veterinary clinics and support residency training in anatomic pathology.

Microscopic view of dead tissue

Services for Referring Veterinarians

Specimen Submission Guidelines

  1. Containers must be labeled with names of the veterinarian, owner, and animal. If multiple samples are submitted from one animal, each tissue should be submitted in a separate container and labeled appropriately
  2. For margins check on mass excisions, please identify margins with sutures or a tissue ink and specify on submission form locations of each. Special stains if needed are included in the price of the original submission.  If your case can benefit from ancillary immunohistochemistry testing, recommendations are in included in the report.  You may call Histology, 919 513-6390 to authorize the additional testing.
  3. Tissues allowed to fix for 24 hour in appropriate amounts of formalin can be submitted in reduced amounts of fixative, decreasing the size and weight of the container and shipping requirements.

Surgical Pathology Samples

  • Biopsy and masses with surgical margins
  • Liver Pathology
  • Immunohistochemistry
  • Dermatopathology
  • Histopathology of formalin fixed necropsy tissues are accepted. Gross necropsies are not performed on referral  cases

Descriptions of Test complexities

Send In Slide Review

Second opinion on a surgical pathology case (NO cytology).  Up to 2 H&E slides read for one fee.  Slides from an outside reference laboratory should be shipped directly to the Surgical Pathology Service.  The completed submission form can be emailed separately to:  Special stains or immunohistochemistry is an additional charge.

Biopsies 1-2 sites 

Punch, endoscopic, tru-cut biopsies or lesions less than 2cm in diameter. Up to 2 different anatomic sites.  Examples include:  GI biopsies from multiple areas of intestine, skin punch biopsies from 3 different sites on body, biopsies from different liver lobes, also includes feline and canine enucleation.  Small excisional biopsies nodules less than 2 cm.

Additional Biopsy site

Same type as above
Mass <5 cm
any mass or organ 5 cm or less in diameter. This is a per mass charge.  If it is determined that the number of cassettes are less than expected we may charge additional masses less (as an additional biopsy instead).
Mass > 5 cm
Any mass or organ greater than 5 cm in diameter. This is a per mass charge. If it is determined that the number of cassettes are less than expected we may charge additional masses less as an additional biopsy instead).
Liver pathology
One liver biopsy with 4 special stains included: iron, reticulin, sirius red and copper (NOT quantitative).
Send in necropsy tissues
Up to 8 tissues from one animal, trimmed at the referring clinic and shipped in formalin. We do not perform whole animal autopsy on referral cases. Animals with a previously established patient history at the CVM Teaching Hospital can be autopsied. Contact the service where the patient was seen to arrange.

Click Here for Surgical Pathology Submission form

Price List

Research Histology

Services Offered

We strongly recommend you call ahead 919-513-6390 or email: for information regarding the appropriate submission of research samples to the laboratory including establishing your account and authorizing charges as well as the technical content of your project.

  • Routine paraffin techniques
  • Special and Immunohistochemical staining
  • Specialized research protocols are evaluated on a case by case basis
  • Research Techniques include:
    • Routine paraffin processing including special stains and immunohistochemistry*Plastic (Glycol Methacrylate) embedment for soft tissues, sectioning and staining at 2 microns
    • Frozen section services including snap freezing of fresh soft tissues, and infiltration and embedment of  fixed and decaled specimens
    • Provides training to graduate students and laboratory personnel in histologic and immunohistochemistry protocols
    • Development of protocols for new antibodies

Research and Teaching Submission Guidelines electronic file

Research Submission Form Electronic File

Research Account Set up Electronic file

Current Research price list   Electronic  file

Development of IHC protocols antibody validations – instructions electronic file