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Christopher Mariani, DVM, PhD, DACVIM

Associate Professor, Neurology

Office: 919.513.0302

Bachelor of Science (BSc), College of Biological Science, 1996, University of Guelph, Guelph, Ontario, Canada
Doctor of Veterinary Medicine (DVM), 1996, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada
Doctor of Philosophy (PhD), 2006, College of Medicine, University of Florida, Gainesville, Florida
Diplomate, American College of Veterinary Internal Medicine (Neurology)
Spontaneous Animal Disease Models, Veterinary Cancer Care
brain tumor characterization and therapy, epilepsy, inflammatory brain disease

  • (2017) Evaluation of the Lactate Plus monitor for plasma lactate concentration measurement in dogs.Nye CJ, Musulin SE, Hanel RM, Mariani CL. | J Vet Emerg Crit Care 2017 Jan;27(1):66-70. Epub 2016 Dec 14.
  • (2017) The effect of cranberry extract on the frequency of bacteriuria in dogs following acute thoracolumbar disc herniation: a randomized controlled clinical trial.Olby NJ, Vaden S, Williams K, Griffith E, Harris T, Mariani C, Munana K, Early P, Platt S, Boozer L, Giovanella C, Longshore R. | J Vet Intern Med, 2017 Jan;31(1):60-68. doi: 10.1111/jvim.14613. Epub 2016 Dec 3.
  • (2016) A Placebo-Controlled, Prospective, Randomized Clinical Trial of Polyethylene Glycol and Methylprednisolone Sodium Succinate in Dogs with Intervertebral Disk Herniation.Olby NJ, Muguet-Chanoit, Lim JH, Davidian M, Mariani CL, Freeman AC, Platt SR, Humphrey J, Kent M, Giovanella C, Longshore R, Early PJ, Muñana KR | Journal of Veterinary Internal Medicine 2016 Jan;30(1):206-14
  • (In Press) Tumours of the Nervous System. Mariani CL.  | In:  Lascelles BDX and Dobson JM.  BSAVA Manual of Canine and Feline Oncology, 3rd edition.  In Press.
  • (2014) Morbidity and Mortality in Dogs Undergoing Anesthesia and Cervical Spinal SurgeryLP Posner, CL Mariani, C Swanson, M Asakawa, N Campbell, AS King | Vet Anaesth Analg 2014. 41:137-144.
  • (2012) Evaluation of levetiracetam as adjunctive treatment for refractory canine epilepsy: A randomized, placebo-controlled, cross-over trial.Muñana KR, Thomas WB, Inzana KD, Nettifee-Osborne JA, McLucas KJ, Olby NJ, Mariani CM, Early PJ. | Journal of Veterinary Internal Medicine 2012; 26:341-348.
  • (2011) Diazepam pharmacokinetics after nasal drop and atomized nasal adminstration in dogs.Musulin SE, Mariani CL, Papich MG.  | Journal of Veterinary Pharmacology and Therapeutics 2011 Feb;34(1):17-24.
  • (2010) Neuromuscular Junction Disease. Mariani CL.  | In:  Ettinger SJ and Feldman EC, eds.  Textbook of Veterinary Internal Medicine, 7th edition. St. Louis, MO: Saunders Elsevier; 2010:1473-1477.
  • (2010) Peripheral Nerve Disorders.Mariani CL.  | In:  Ettinger SJ and Feldman EC, eds.  Textbook of Veterinary Internal Medicine, 7th edition. St. Louis, MO: Saunders Elsevier; 2010:1462-1467.
  • (2009) IDH1 and IDH2 hotspot mutations are not found in canine glioma. Reitman ZJ, Olby NJ, Mariani CL, Thomas R, Breen M, Bigner DD, McLendon RE, Yan H.  | International Journal of Cancer 2009 Epub Oct 29, DOI 10.1002/ijc.25017.
  • (2009) Intracranial Meningioma in dogs and cats. A comparative review.Sessums K, Mariani CL.  | Compendium of Continuing Education for Veterinarians, 2009;31(7):330-339.
  • (2008) Bromodeoxyuridine inhibits cancer cell proliferation in vitro and in vivo. Levkoff LH, Marshall GP, Ross HH, Calderia M, Reynolds BA, Cakiroglu M, Mariani CL, Streit WJ, Laywell ED.  | Neoplasia, 2008;10(8):804-816.
  • (2007) Head Trauma. Holawaychuk, MK, Hansen, BG, Hanel RM, Marks SL, Mariani CL.  | Standards of Care, Emergency and Critical Care Medicine.  2007;9(6):1-8,16.
  • (2007) The neurologic examination and neurodiagnostic techniques for reptiles.  Mariani CL.  | Veterinary Clinics of North America Exotic Animal Practice, 2007;10:855-891.
  • (2007) Nonspecific immunotherapy with intratumoral lipopolysaccharide and zymosan A but not GM-CSF leads to an effective anti-tumor response in subcutaneous RG-2 gliomas.Mariani CL, Rajon D, Bova FJ, Streit WJ.  | Journal of neuro-oncology 2007;85(3):231-240.
  • (2007) Teratoma in the cervical spinal cord of a dog. Wong M, Mariani CL, Powe J, Clemmons RM.  | Journal of the American Animal Hospital Association 2007;43:292-297.
  • (2006) Rejection of RG-2 gliomas is mediated by microglia and T lymphocytes.Mariani CL , Kouri JG, Streit WJ. | Journal of Neuro-oncology, 2006;79:243-253.
  • (2005) Role of microglia in the central nervous system's immune response.Streit WJ, Conde JR, Fendrick SE, Flanary BE, Mariani CL. | Neurological Research 2005; 27:685-691.
  • (2004) Dancing Doberman Disease.Mariani CL. | In: CD Canis. Kansas City: Vetstream, Inc., 2004.
  • (2004) Clinical signs, underlying cause and outcome in cats with seizures: 17 cases (1997-2002).Barnes HL, Chrisman CL, Mariani CL, Sims M, Allemand AR. | Journal of the American Veterinary Association 2004; 225:1723-1726.
  • (2003) Neurology for the Small Animal Practitioner. Jackson :Chrisman CL, Mariani CL, Platt SR, Clemmons RM. | Teton NewMedia, 2003;1-353.
  • (2003) Spongy Degeneration.Mariani CL. | In: CD Canis. Kansas City: Vetstream, Inc., 2003.
  • (2003) Full recovery following d elayed neurologic signs after smoke inhalation in a dog.Mariani CL. | Journal of Veterinary Emergency and Critical Care 2003;13:235-239.
  • (2003) Diagnosis of a porto-azygyous shunt using helical computed tomography angiography.Thompson MS, Graham JP, Mariani CL. | Veterinary Radiology & Ultrasound 2003;44:287-291.
  • (2002) Cerebral phaeohyphomycosis caused by Cladosporium spp. in two domestic short-haired cats.Mariani CL, Platt SR, Scase TJ, Howerth EW, Chrisman CL, Clemmons RM. | Journal of the American Animal Hospital Association 2002; 38:225-230.
  • (2001) Magnetic resonance imaging of cerebral cortical necrosis (polioencephalomalacia) in a dog.Mariani CL, Platt SR, Newell SM, Terrell SP, Chrisman CL, Clemmons RM. | Veterinary Radiology & Ultrasound 2001; 42:524-531.
  • (2001) Magnetic resonance imaging of spongy degeneration of the central nervous system in a Labrador retreiver.Mariani CL, Clemmons RM, Graham JP, Phillips LA, Chrisman CL. | Veterinary Radiology & Ultrasound 2001; 42:285-290.
  • (2001) Atypical reaction to acetaminophen intoxication in a dog.Mariani CL, Fulton RB Jr. | Journal of Veterinary Emergency and Critical Care 2001; 11:123-126.
  • (1999) Paraneoplastic polyneuropathy and subsequent recovery following tumor removal in a dog.Mariani CL, Shelton SB, Alsup JC. | Journal of the American Animal Hospital Association 1999; 35:302-305.