Duncan Lascelles
Bio
After graduating from the veterinary program at the University of Bristol, U.K., with honors, in 1991 Dr. Lascelles completed a PhD in aspects of pre-emptive/perioperative analgesia at the University of Bristol. After an internship there, he completed his surgical residency at the University of Cambridge, U.K. He moved to Colorado for the Fellowship in Oncological Surgery at Colorado State University, then a period of post-doctoral research in feline pain and analgesia at the University of Florida, and is currently Professor in Small Animal Surgery and Pain Management at North Carolina State University. He is board-certified in small animal surgery by the Royal College of Veterinary Surgeons, the European College of Veterinary Surgeons, and the American College of Veterinary Surgeons.
He is director of the Comparative Pain Research and Education Centre (CPREC). His research program (Translational Research in Pain [TRiP]) is dedicated to answering critical questions about pain control and pain mechanisms through high quality, innovative research. His career has been focused on developing algometry methods (methods to measure pain) in spontaneous disease animal models (pets with naturally occurring disease), and probing tissues from well-phenotyped animals with spontaneous disease to understand the neurobiology, with a strong translational focus. The aim of his research is to improve pain control in companion animals, and facilitate analgesic development in human medicine. He has authored over 180 peer reviewed research papers and reviews and 190 research abstracts, as well as over 30 book chapters.
AFFILIATIONS
International Association for the Study of Pain (IASP), member
IASP Special Interest Group on Non-Human Pain
Chair, World Small Animal Veterinary Association Global Pain Council
Thurston Arthritis Center, Medical School, UNC Chapel Hill, member
Center for Translational Pain Medicine, Duke University, member
CERTIFICATIONS
Fellow of the Royal College of Veterinary Surgeons
Diplomate, American College of Veterinary Surgeons
Diplomate, European College of Veterinary Surgeons
Diploma of the Royal College of Veterinary Surgeons, Soft Tissue Surgery
Area(s) of Expertise
NEUROBIOLOGY, PHARMACOLOGY, REGENERATIVE MEDICINE, VETERINARY CANCER CARE
Dr. Lascelles' research is focused on developing algometry methods in spontaneous disease animal models (i.e. developing ways to measure the many dimensions impacted by pain), and probing tissues from well-phenotyped animals with spontaneous disease to understand the neurobiology of that pain. The two fundamental aims of his research are: 1) to improve pain control in companion animals, and 2) to facilitate analgesic development in human medicine though using companion animals with spontaneous (naturally occurring) disease.
Publications
- Activity patterns are associated with fractional lifespan, memory, and gait speed in aged dogs , SCIENTIFIC REPORTS (2023)
- Acute radiotherapy-associated oral pain may promote tumor growth at distant sites , FRONTIERS IN ONCOLOGY (2023)
- An Exploration of Machine Learning Methods for Gait Analysis of Potential Guide Dogs , TENTH INTERNATIONAL CONFERENCE ON ANIMAL-COMPUTER INTERACTION, ACI 2023 (2023)
- COAST Development Group's international consensus guidelines for the treatment of canine osteoarthritis , FRONTIERS IN VETERINARY SCIENCE (2023)
- Development and validation of a sleep questionnaire, SNoRE 3.0, to evaluate sleep in companion dogs , SCIENTIFIC REPORTS (2023)
- Minimal clinically-important differences for the 'Liverpool Osteoarthritis in Dogs' (LOAD) and the 'Canine Orthopedic Index' (COI) client-reported outcomes measures , PLOS ONE (2023)
- Multi-Functional Small Molecule Alleviates Fracture Pain and Promotes Bone Healing , ADVANCED SCIENCE (2023)
- Nine-axis inertial measurement unit output discriminates activities of varying intensity in the dog , AMERICAN JOURNAL OF VETERINARY RESEARCH (2023)
- Pain sensitivity differs between dog breeds but not in the way veterinarians believe , FRONTIERS IN PAIN RESEARCH (2023)
- Study of the effectiveness of glucosamine and chondroitin sulfate, marine based fatty acid compounds (PCSO-524 and EAB-277), and carprofen for the treatment of dogs with hip osteoarthritis: A prospective, block-randomized, double-blinded, placebo-controlled clinical trial , FRONTIERS IN VETERINARY SCIENCE (2023)
Groups
- CVM: Clinical Sciences
- CVM
- Clinical Sciences: DOCS Faculty
- Clinical Sciences: DOCS Orthopedics Faculty
- CVM: Feline Health
- CVM: Focus Area
- Focus Area: Graduate Cell Biology
- Focus Area: Graduate Pharmacology
- CVM: Hospital
- Research Area of Emphasis: Neurobiology
- Hospital: Orthopedics
- Research Area of Emphasis: Pharmacology
- Research Area of Emphasis: Regenerative Medicine
- CVM: Research Area of Emphasis
- Focus Area: Small Animal Practice
- Research Area of Emphasis: Veterinary Cancer Care
News
- Lascelles Named DuBose Distinguished Professor
- A Match Made in Rehab for NC State Veterinary Technician, Hunting Dog
- Cartilage Resurfacing Implant Reduces Pain, Restores Hip Joint Function in Dogs
- New NC State Veterinary Medicine Project Aims to Unlock Mysteries of Dog Pain
- Study Sets Baseline for Sleep Patterns in Healthy Adult Dogs
- Dual DVM/Ph.D. Student Earns Award for Groundbreaking Canine Osteoarthritis Research
- NC State CVM Awarded 3 Winn Feline Foundation Research Grants
- A Once-Neglected Stray Receives an Unforgettable Memorial
- Companion Animals May Hold the Key to Human Pain Relief
- Foster, Lascelles Awarded Pharmacology Research Grants