Dr. Scharf earned a Bachelor of Science in Earth Systems from Stanford University and her DVM degree from Texas A&M University prior to completing a rotating internship at The Ohio State University. She completed a surgical residency and earned her MS focusing on translational oncology at the University of Florida. Her research interests include minimally invasive surgery, spontaneous pneumothorax, surgical oncology and endocrine neoplasia, and the role of companion animals as models of environmental exposure. She also has a strong interest in teaching and developing new strategies for surgical education.
Diplomate American College of Veterinary Surgeons
Small Animal Surgery Residency University of Florida
Small Animal Rotating Internship The Ohio State University
Doctor of Veterinary Medicine Texas A&M University
Bachelor of Science Stanford University
Area(s) of Expertise
SPONTANEOUS ANIMAL DISEASE MODELS, VETERINARY CANCER CARE
Development of novel minimally invasive surgical modalities.
Role of companion animals as models of environmental exposure and disease.
Thyroid neoplasia and dysfunction.
Etiology and treatment of spontaneous pneumothorax.
- A narrative review of the impact of work hours and insufficient rest on job performance , VETERINARY SURGERY (2023)
- A narrative review of the physiology and health effects of burnout associated with veterinarian-pertinent occupational stressors , FRONTIERS IN VETERINARY SCIENCE (2023)
- Surgical technique and complications associated with laparoscopic pleuroperitoneal diaphragmatic herniorrhaphy in a dog , VETERINARY RECORD CASE REPORTS (2023)
- Veterinarian burnout demographics and organizational impacts: a narrative review , FRONTIERS IN VETERINARY SCIENCE (2023)
- Complications and outcomes of thoracoscopic-assisted lung lobectomy in dogs , VETERINARY SURGERY (2022)
- Distribution of histopathologic types of primary pulmonary neoplasia in dogs and outcome of affected dogs: 340 cases (2010-2019) , JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION (2022)
- Dogs >= five years of age at the time of congenital extrahepatic portosystemic shunt diagnosis have better long-term outcomes with surgical attenuation than with medical management alone , JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION (2022)
- Outcome in 38 dogs surgically treated for hepatic abscessation , VETERINARY SURGERY (2022)
- Perioperative characteristics, histologic diagnosis, complications, and outcomes of dogs undergoing percutaneous drainage, sclerotherapy or surgical management of intrarenal cystic lesions: 18 dogs (2004-2021) , BMC VETERINARY RESEARCH (2022)
- Sleep patterns, fatigue, and working hours among veterinary house officers: a cross-sectional survey study , JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION (2022)
Primary spontaneous pneumothorax (PSP) is defined as the presence of air within the pleural space without an obvious precipitating factor. This disease presents as a life-threatening emergency causing shortness of breath, exercise intolerance, and possible collapse or sudden death, affecting an average of 13 dogs per year at our institution. Although the overall prevalence is fairly low, PSP is of great importance due to the impact on the individual dog. Treatment of PSP in dogs remains challenging. Current standard of care dictates full thoracic exploration via an invasive median sternotomy followed by resection of affected lung lobes. Video-assisted thoracoscopic surgery (VATS) is preferred over open thoracotomy in human medicine as it is associated with lower morbidity and reduced post-operative pain, making it a desirable alternative to the current standard in veterinary medicine. Historical limitations in correctly identifying pulmonary bullae associated with spontaneous pneumothorax in dogs has limited the usefulness of VATS. Investigators have recently established the efficacy of using a variable angle endoscope to thoracoscopically identify pulmonary bullae in dogs. Additionally, autologous blood injection has been demonstrated in people to seal leaking lung tissue. Thus, this pilot study aims to prospectively evaluate the efficacy of minimally invasive autologous blood injection to treat primary spontaneous pneumothorax in dogs. We hypothesize that thoracoscopic autologous blood injection will effectively seal pulmonary bullae and blebs in dogs with primary spontaneous pneumothorax, facilitating minimally invasive treatment of this disease in dogs with potential extension to treating primary spontaneous pneumothorax in people.
Hypothesis: We hypothesize that ICG can be repeatedly administered without persistence of parathyroid gland fluorescence and without a cumulative dose effect, and that fluorescence of the parathyroid glands will subside within 10 minutes of initial observation of fluorescence. We also hypothesize that both external and internal parathyroid glands will fluoresce and that 0.015 mg/kg administered once intravenously will provide optimal parathyroid gland fluorescence. Specific Aims: The objective of the pilot study is to evaluate for a potential cumulative dose effect on fluorescence of parathyroid glands with repeated ICG administration and to measure the time to peak fluorescence and subsidence of fluorescence following repeated ICG dosage. The objective of the subsequent dose optimization study is to determine the optimal intravenous ICG dosage and timing to detect normal parathyroid glands using NIRF imaging in dogs. A secondary objective is to assess the degree of fluorescence and feasibility of visualization of both external and internal parathyroid glands using ICG NIRF to aid in intraoperative identification.
Primary spontaneous pneumothorax is defined as the presence of air within the pleural space without an obvious precipitating factor. Large breed, deep-chested dogs, particularly Huskies and hunting breeds, are most commonly affected. Development of this disease is associated with the presence of pulmonary bullae. The diagnosis and localization of pulmonary bullae in dogs remains challenging; thus the objective of this study is to evaluate the feasibility of a minimally invasive diagnostic procedure (variable-angle thoracoscopy) for identification and localization of pulmonary bullae.
The objective of this study is to describe and assess a novel intraoperative NIRF imaging technique using aerosolized ICG to visualize healthy pulmonary parenchyma thoracoscopically, and to evaluate clinical feasibility of this technique in a canine model. A secondary objective is to determine the optimal dosage and timing of administration and to assess acute and delayed effects of inhalational ICG on postoperative pulmonary function and tissue histology.
The objectives of this study are to 1) evaluate a novel minimally invasive approach for attenuation of PA shunts in dogs via thoracoscopic placement of ARCs, and to 2) prospectively evaluate the efficacy of thoracoscopically placed ARCs to attenuate PA shunts based on clinical assessment, biochemical values, and diagnostic imaging results.
- CVM: Clinical Sciences
- Clinical Sciences: DOCS Faculty
- Clinical Sciences: DOCS Soft Tissue Faculty
- CVM: Focus Area
- CVM: Hospital
- CVM: Research Area of Emphasis
- Focus Area: Small Animal Practice
- Hospital: Small Animal Soft Tissue Surgery
- Research Area of Emphasis: Spontaneous Animal Disease Models
- Research Area of Emphasis: Veterinary Cancer Care