Pharmacology
Overview
Graduate work in the Pharmacology Concentration Area includes research at the molecular and cellular level in pharmacology, pharmacokinetics, drug interactions, drug residues and metabolites, anesthetics and autonomic drugs, pulmonary biology, oncology, ophthalmology, gastroenterology, reproductive endocrinology, and lipid-, peptide-, and oxygen-derived mediators of inflammation. Research approaches employ a wide variety of molecular, biochemical, pharmacological, and microscopic techniques, utilizing cell culture and whole organisms. Students selecting Pharmacology will focus on one or more of these areas.
A highly individualized curriculum of study is designed to meet the needs and interests of the student while satisfying selected requirements by the faculty. These include courses in introductory pharmacology and toxicology, advanced pharmacology, pharmacokinetics, statistics, and participation in a seminar series in pharmacology. Additional courses may be chosen by the student and his/her advisor from a large number of college and university offerings.
COURSES REQUIRED FOR THE PHARMACOLOGY CONCENTRATION
BCH 553 Biochemistry of Gene Expression; Fall, Spring, & Summer (3 credits)
TOX 701 Fundamentals of Toxicology; Fall (3 credits)
TOX 710 Molecular and Biochemical Toxicology; Spring (3 credits)
CBS 762 Principles in Pharmacology; Spring (3 credits)
CBS 787 Pharmacokinetics; Fall alternate years (3 credits)
CBS 810 Seminar in Pharmacology (1 credit; minimum 3 credits total)
CBS 860 Techniques in Pharmacological Research; Fall (2 credits)
ELECTIVE COURSES
Elective courses are selected by the student and mentor, and must be approved by the student’s graduate advisory committee. Possible elective course include, but are not limited to, the following:
PB 495/595-011, ECE 492-030/592-038, & CBS 595-011 Systems Biology Modeling of Multicellular Organisms; Fall (3 credits)
ST 512 Experimental Statistics For Biological Sciences II; Fall/Spring/Summer (3 credits)
Pharmacology Participating Faculty
| Name | Primary Concentration | Other Concentrations | Research Emphasis | |
|---|---|---|---|---|
| Alex Lynch | amlynch3@ncsu.edu | Pharmacology | Hemostasis | In addition to his clinical duties, Dr. Lynch undertakes research with a particular interest in coagulation and transfusion medicine. |
| Belinda Akpa | bsakpa@ncsu.edu | Pharmacology | Cell Biology | Mechanistic mathematical modeling |
| Brian Gilger | bgilger@ncsu.edu | Pharmacology | Cell Biology | Ocular inflammation, drug delivery, gene therapy, fungal keratitis, and imaging of the eye |
| Chris McGahan | mcmcgaha@ncsu.edu | Pharmacology | Cell Biology | Regulation of Fe metabolism in the eye, the involvement of Fe in cataract formation, and mechanisms underlying post-surgical regrowth of lens tissue |
| David Dorman | david_dorman@ncsu.edu | Neurosciences | Pharmacology | My research interests include neurotoxicology and cognition and olfaction in animals |
| Derek Foster | derek_foster@ncsu.edu | Infectious Diseases | Pharmacology, Population Medicine | We use pharmacokinetic modeling to understand antimicrobial resistance in enteric bacteria. |
| Geof Smith | gwsmith@ncsu.edu | Pharmacology | Pathophysiology and treatment of diseases affecting calves, ruminant pharmacology, food safety and prevention of drug residues | |
| Glenn Cruse | gpcruse@ncsu.edu | Immunology | Pharmacology, Cell Biology | Translational research in mast cell-driven diseases such as allergy, asthma and mastocytosis. |
| Jian Zhang | jzhan257@ncsu.edu | Pharmacology | The primary focus of the Zhang Group lies in the development of stimuli-responsive hydrogels (bio-adhesive), targeted drug delivery systems, and portable devices aimed at tackling critical biomedical challenges that play essential roles in human life. | |
| Kristen Messenger | kmmessen@ncsu.edu | Pharmacology | The Messenger lab research focus is on the pharmacokinetics and pharmacodynamics of analgesic drugs. | |
| Mark Papich | mgpapich@ncsu.edu | Pharmacology | Research in medications administered to animals | |
| Melissa Christina Srougi | mcsrougi@ncsu.edu | Cell Biology | Pharmacology | experimental cancer chemotherapeutics, DNA damage responses, redox, metabolism, cancer |
| Michael Stoskopf | mkstosko@ncsu.edu | Pharmacology | Population Medicine | Ecological Metabolomics |
| Ronald Baynes | rebaynes@ncsu.edu | Pharmacology | Comparative Pharmacokinetics and Risk Management of Drug Residues | |
| Russell Borski | russell_borski@ncsu.edu | Cell Biology | Pharmacology | Studies endocrinology and the adaptive stress response in vertebrates |
| Steven Marks | slmarks@ncsu.edu | Pharmacology | ||
| Yevgeny Brudno | ybrudno@ncsu.edu | Pharmacology | Immunology, Neurosciences | Drug delivery to the brain and to cancer. |